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Stem cells from muscle can repair nerve damage after injury, Pitt researchers show

By daniellenierenberg

PUBLIC RELEASE DATE: 18-Mar-2014 Contact: Anita Srikameswaran 412-578-9193 University of Pittsburgh Schools of the Health Sciences PITTSBURGH, March 18, 2014 Stem cells derived from human muscle tissue were able to repair nerve damage and restore function in an animal model of sciatic nerve injury, according to researchers at the University of Pittsburgh School of Medicine. The findings, published online today in the Journal of Clinical Investigation, suggest that cell therapy of certain nerve diseases, such as multiple sclerosis, might one day be feasible. To date, treatments for damage to peripheral nerves, which are the nerves outside the brain and spinal cord, have not been very successful, often leaving patients with impaired muscle control and sensation, pain and decreased function, said senior author Johnny Huard, Ph.D., professor of orthopaedic surgery, and Henry J

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Spinal cord injuries: how could stem cells help? | Europe …

By JoanneRUSSELL25

Introducing the spinal cord The spinal cord is the delicate tissue encased in and protected by the hard vertebrae of the spinal column. Together the brain and spinal cord form the bodys central nervous system.

To Read More: Spinal cord injuries: how could stem cells help? | Europe …
categoriaSpinal Cord Stem Cells commentoComments Off on Spinal cord injuries: how could stem cells help? | Europe … | dataMarch 18th, 2014
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Final Results Of Neuralstem Phase I Stem Cell Trial In Amyotrophic Lateral Sclerosis Published In Annals of Neurology

By LizaAVILA

Neuralstem Logo.

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Stem Cell Research in pursuit of Spinal Cord Injury …

By Sykes24Tracey

(Page 1 of 2) Because neurons (nerve cells) in the central nervous system (the brain and spinal cord) do not repair or replace themselves after being injured, researchers are investigating whether transplanting cells into an injured area can restore function. One of the many challenges for researchers is obtaining cells that will function as neurons in the brain or spinal cord

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categoriaSpinal Cord Stem Cells commentoComments Off on Stem Cell Research in pursuit of Spinal Cord Injury … | dataMarch 14th, 2014
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New findings on neurogenesis in spinal cord

By LizaAVILA

Research from Karolinska Institutet in Sweden suggests that the expression of the so called MYC gene is important and necessary for neurogenesis in the spinal cord. The findings are being published in the journal EMBO Reports.

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categoriaSpinal Cord Stem Cells commentoComments Off on New findings on neurogenesis in spinal cord | dataMarch 5th, 2014
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Hot on the trail of cellular metabolism: Researchers unravel the function of cell proteins

By NEVAGiles23

14 hours ago This image shows an embryonic stem cell differentiating into a neuronal cell. Credit: Anne Rupprecht/Vetmeduni Vienna Cells have a metabolism that can be altered according to its function. If cellular metabolism is disturbed, it can lead to disease of the entire organism

To Read More: Hot on the trail of cellular metabolism: Researchers unravel the function of cell proteins
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CIRM Stem Cell Research Updates: Team tricked scar tissue …

By Sykes24Tracey

They used a process similar to one they used in an earlier project published last September where they reported creating neural networks in the brains of mice. In both cases the researchers reprogrammed the nerve support cells known as astrocytes into functional nerves. Astrocytes tend to be abundant, particularly at the site of injury where they proliferate and form scar tissue that actually prevents regrowth of the damaged nerves

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categoriaSpinal Cord Stem Cells commentoComments Off on CIRM Stem Cell Research Updates: Team tricked scar tissue … | dataMarch 1st, 2014
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Nygrd uses stem cells to pursue immortality

By admin

The video begins like a clip from a James Bond movie, where the billionaire tycoon announces his plan to save humanity. "Since the dawn of time, great men have challenged the status quo and dared to dream," an off-screen female narrator says in a sultry British accent while images of Leonardo da Vinci, Martin Luther King and other great historical figures parade across the screen. The great man in question is none other than Peter Nygrd, the Helsinki-born, Manitoba-raised fashion magnate best known as the founder of Nygrd International.

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categoriaSpinal Cord Stem Cells commentoComments Off on Nygrd uses stem cells to pursue immortality | dataFebruary 28th, 2014
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New neurons generated in brains, spinal cords of living adult mammals

By raymumme

UT Southwestern Medical Center researchers created new nerve cells in the brains and spinal cords of living mammals without the need for stem cell transplants to replenish lost cells. Although the research indicates it may someday be possible to regenerate neurons from the body's own cells to repair traumatic brain injury or spinal cord damage or to treat conditions such as Alzheimer's disease, the researchers stressed that it is too soon to know whether the neurons created in these initial studies resulted in any functional improvements, a goal for future research.

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Researchers Generate New Neurons in Brains, Spinal Cords of Living Adult Mammals Without the Need of Stem Cell …

By JoanneRUSSELL25

Contact Information Available for logged-in reporters only Newswise DALLAS, Feb.

To Read More: Researchers Generate New Neurons in Brains, Spinal Cords of Living Adult Mammals Without the Need of Stem Cell …
categoriaSpinal Cord Stem Cells commentoComments Off on Researchers Generate New Neurons in Brains, Spinal Cords of Living Adult Mammals Without the Need of Stem Cell … | dataFebruary 25th, 2014
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Helping people with spinal cord injuries

By JoanneRUSSELL25

REGINA Meeting Rick Hansen during his Man in Motion world tour sparked six-year-old Josef Buttigiegs fascination with biology and set his career course in motion. Twenty-eight years after first meeting Hansen, Buttigieg is a biology professor at the University of Regina.

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categoriaSpinal Cord Stem Cells commentoComments Off on Helping people with spinal cord injuries | dataFebruary 21st, 2014
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Deep TCR sequencing reveals extensive renewal of the T cell repertoire following autologous stem cell transplant in MS

By NEVAGiles23

A new study describes the complexity of the new T cell repertoire following immune-depleting therapy to treat multiple sclerosis, improving our understanding of immune tolerance and clinical outcomes. In the Immune Tolerance Network's (ITN) HALT-MS study, 24 patients with relapsing, remitting multiple sclerosis received high-dose immunosuppression followed by a transplant of their own stem cells, called an autologous stem cell transplant, to potentially reprogram the immune system so that it stops attacking the brain and spinal cord. Data published in the Journal of Clinical Investigation quantified and characterized T cell populations following this aggressive regimen to understand how the reconstituting immune system is related to patient outcomes.

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Extensive renewal of the T cell repertoire following autologous stem cell transplant in MS

By JoanneRUSSELL25

PUBLIC RELEASE DATE: 17-Feb-2014 Contact: Philip Bernstein, Ph.D. ITNCommunications@immunetolerance.org 240-235-6132 Immune Tolerance Network WA, Seattle (February 17, 2014) A new study describes the complexity of the new T cell repertoire following immune-depleting therapy to treat multiple sclerosis, improving our understanding of immune tolerance and clinical outcomes

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categoriaSpinal Cord Stem Cells commentoComments Off on Extensive renewal of the T cell repertoire following autologous stem cell transplant in MS | dataFebruary 18th, 2014
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Deep TCR Sequencing Reveals Extensive Renewal of the T Cell Repertoire Following Autologous Stem Cell Transplant in …

By LizaAVILA

Contact Information Available for logged-in reporters only Newswise WA, Seattle (February 17, 2014) A new study describes the complexity of the new T cell repertoire following immune-depleting therapy to treat multiple sclerosis, improving our understanding of immune tolerance and clinical outcomes. In the Immune Tolerance Networks (ITN) HALT-MS study, 24 patients with relapsing, remitting multiple sclerosis received high-dose immunosuppression followed by a transplant of their own stem cells, called an autologous stem cell transplant, to potentially reprogram the immune system so that it stops attacking the brain and spinal cord. Data published today in the Journal of Clinical Investigation (http://www.jci.org/articles/view/71691?key=b64763243f594bab6646) quantified and characterized T cell populations following this aggressive regimen to understand how the reconstituting immune system is related to patient outcomes.

To Read More: Deep TCR Sequencing Reveals Extensive Renewal of the T Cell Repertoire Following Autologous Stem Cell Transplant in …
categoriaSpinal Cord Stem Cells commentoComments Off on Deep TCR Sequencing Reveals Extensive Renewal of the T Cell Repertoire Following Autologous Stem Cell Transplant in … | dataFebruary 18th, 2014
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StemCells, Inc. Expands Phase I/II Spinal Cord Injury …

By Sykes24Tracey

StemCells, Inc.

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Melson keeps fighting

By Sykes24Tracey

By Matt Richardson Photos by Ed Mulholland Junior middleweight Boyd Melson has a fight scheduled for tomorrow night at the Roseland Ballroom in Manhattan against Donald Ward. Its a fight that Melson (13-1-1, 4 KOs) says he expects will be difficult, despite Ward being a late replacement for veteran Mike Ruiz.

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categoriaSpinal Cord Stem Cells commentoComments Off on Melson keeps fighting | dataFebruary 12th, 2014
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New Brain-Image Database Could Help People With Chronic Pain

By JoanneRUSSELL25

Up To 500,000 Spinal Cord Injuries Per Year Worldwide The World Health Organization says as many as 500,000 people suffer spinal cord injuries every year.

To Read More: New Brain-Image Database Could Help People With Chronic Pain
categoriaSpinal Cord Stem Cells commentoComments Off on New Brain-Image Database Could Help People With Chronic Pain | dataFebruary 12th, 2014
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Toxin from Brain Cells Triggers Neuron Loss in Human ALS Model

By daniellenierenberg

Contact Information Available for logged-in reporters only Newswise NEW YORK, NY (February 6, 2014) In most cases of amyotrophic lateral sclerosis (ALS), or Lou Gehrigs disease, a toxin released by cells that normally nurture neurons in the brain and spinal cord can trigger loss of the nerve cells affected in the disease, Columbia researchers reported today in the online edition of the journal Neuron. The toxin is produced by star-shaped cells called astrocytes and kills nearby motor neurons

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Medical Center Researchers Create Human ALS Model That May Lead to New Therapies

By Sykes24Tracey

New details about how motor neurons die in ALS have been uncovered by a new cell-culture system that combines spinal cord or brain cells from ALS patients with human motor neurons. The culture system shows that patient astrocytes (shown here with a blue-stained nucleus) release a toxin that kills motor neurons via a recently discovered process described as a controlled cellular explosion. Image: Diane Re.

To Read More: Medical Center Researchers Create Human ALS Model That May Lead to New Therapies
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The ethics of medical progress

By daniellenierenberg

A new method of producing stem cells is being described as a "game-changing" scientific breakthrough. It is said that the research, carried out by scientists in Japan, could hail a new era of personalised medicine, offering hope to sufferers of diseases such as stroke, heart disease and spinal cord injuries. The scientists bathed blood cells in a weak acidic solution for half an hour, which made the adult cells shrink and go back to their embryonic stem cell state

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categoriaSpinal Cord Stem Cells commentoComments Off on The ethics of medical progress | dataFebruary 1st, 2014
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