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Regulating Bone Marrow Protein can Improve Stem Cell Transplants – CMFE News (press release) (blog)

By JoanneRUSSELL25

A recent study has identified a key protein capable of regulating the process of new blood cells, including immune cells, which can potentially improve bone and stem cell transplants for donors as well as recipients. The researchers at Technical University of Dresden, Germany, led by the University of Pennsylvania, USA, found that a protein known as Del-1 occupies a key role in the process of hematopoiesis. In addition, researchers inferred that the protein regulator may be modulated to act as potential drug targets in patients affected by certain blood cancers types

To Read More: Regulating Bone Marrow Protein can Improve Stem Cell Transplants – CMFE News (press release) (blog)
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Chemo-Boosting Drug Discovered for Leukemia – Futurism

By NEVAGiles23

In BriefResearchers have discovered that acute myeloid leukemia causes leaking from the bone marrow that interferes with chemotherapy delivery. If chemotherapy for AML can be used together with drugs to treat this problem, outcomes may improve dramatically.

To Read More: Chemo-Boosting Drug Discovered for Leukemia – Futurism
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Bone marrow transplant – Doctor NDTV

By JoanneRUSSELL25

Wed,17 Dec 2003 05:30:00 Bone marrow transplant is a procedure in which healthy bone marrow is transplanted into a patient whose bone marrow is not functioning properly. Problems in bone marrow are often caused by chemotherapy or radiation treatment for cancer.

To Read More: Bone marrow transplant – Doctor NDTV
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Dr Con Man: the rise and fall of a celebrity scientist who fooled almost everyone – The Guardian

By admin

Scientific pioneer, superstar surgeon, miracle worker thats how Paolo Macchiarini was known for several years. Dressed in a white lab coat or in surgical scrubs, with his broad, handsome face and easy charm, he certainly looked the part

To Read More: Dr Con Man: the rise and fall of a celebrity scientist who fooled almost everyone – The Guardian
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Targeting bone marrow protein could be effective way to improve … – Gears Of Biz

By raymumme

Bone marrow contains hematopoetic stem cells, the precursors to every blood cell type.

To Read More: Targeting bone marrow protein could be effective way to improve … – Gears Of Biz
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In utero stem cell transplants may replace riskier childhood transplants for multiple conditions – Medical Xpress

By LizaAVILA

Tippi MacKenzie, MD, a pediatric and fetal surgeon at UCSF Benioff Childrens Hospital San Francisco, is the principal investigator for a clinical trial that will use in utero stem cell transplants to treat fetuses with an inherited disorder that restricts the bloods ability to carry oxygen to vital organs. Credit: Cindy Chew UCSF Benioff Children's Hospitals in San Francisco and Oakland will pioneer stem cell transplants for a uniquely challenging patient population: second-trimester fetuses stricken with a potentially fatal disease. The two hospitals are enrolling 10 pregnant women in the first phase of a clinical trial to treat fetuses with an inherited disorder that restricts the blood's ability to carry oxygen to vital organs

To Read More: In utero stem cell transplants may replace riskier childhood transplants for multiple conditions – Medical Xpress
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For Lowell native, stem cell match becomes a match as friends – Lowell Sun

By JoanneRUSSELL25

From left to right: Richard Stone, a doctor at Dana-Farber Cancer Institute in Boston, poses with Peter Karalekas (center), 76, and Matthew Churitch, 22. Churitch donated stem cells to Karalekas two years ago, and he visited Dana-Farber with Karalekas earlier this summer. (Courtesy photo) BOSTON -- After winding his way through Massachusetts, Connecticut, New Hampshire and Maine for 76 years, Peter Karalekas has a proclamation: He's a Southerner now

To Read More: For Lowell native, stem cell match becomes a match as friends – Lowell Sun
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Bacterial Infection Stresses Blood Stem Cells – Asian Scientist Magazine

By LizaAVILA

AsianScientist (Aug. 30, 2017) - In a study published in Cell Stem Cell, scientists in Japan and Switzerland have found that bacterial infections can stress blood-producing stem cells in the bone marrow and reduce their ability to self-replicate. When a person becomes infected with a virus or bacteria, immune cells in the blood or lymph react to the infection.

To Read More: Bacterial Infection Stresses Blood Stem Cells – Asian Scientist Magazine
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Nanoparticle Advance Could Yield Multi-Purpose Treatments – Drug Discovery & Development

By JoanneRUSSELL25

A team of scientists found a way to create a novel drug delivery system for an array of different conditions. Researchers at the Fred Hutchinson Cancer Research Center developed a biomedical tool that harnesses nanoparticles to deliver transient gene changes to specified cells. This system extends the therapeutic potential of messenger RNA (mRNA).

To Read More: Nanoparticle Advance Could Yield Multi-Purpose Treatments – Drug Discovery & Development
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In Osteoporosis, differentiation of mesenchymal stem cells …

By LizaAVILA

Biol Res 45: 279-287, 2012 RESEARCH ARTICLES In Osteoporosis, differentiation of mesenchymal stem cells (MSCs) improves bone marrow adipogenesis Ana Mara Pino1, Clifford J.

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FDA Cracks Down on Stem Cell Clinics But Patients Are Still at Risk – TIME

By LizaAVILA

On Monday, the U.S. Food and Drug Administration (FDA) announced that the agency is targeting clinics that offer unproven stem cell therapies, calling such offices "unscrupulous clinics" selling "so-called cures." The FDA seized materials from one clinic in California, and sent a warning letter to another in Florida.

To Read More: FDA Cracks Down on Stem Cell Clinics But Patients Are Still at Risk – TIME
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Frawley, Mindell/Brody, Calkins Awards Recognize 5 for Excellence – UB School of Medicine and Biomedical Sciences News

By LizaAVILA

Resident Asma Mursleen, MD (center) with Roseanne C. Berger, MD (left), and Michael E

To Read More: Frawley, Mindell/Brody, Calkins Awards Recognize 5 for Excellence – UB School of Medicine and Biomedical Sciences News
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Fetal membranes may help transform regenerative medicine – Medical Xpress

By JoanneRUSSELL25

A new review looks at the potential of fetal membranes, which make up the amniotic sac surrounding the fetus during pregnancy, for regenerative medicine. Fetal membranes have been used as biological bandages for skin grafts as well as for serious burns.

To Read More: Fetal membranes may help transform regenerative medicine – Medical Xpress
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Cell Therapy Can Be Fast and Easy: Just Add mRNA Nanocarriers – Genetic Engineering & Biotechnology News

By raymumme

Essentially, nanoparticles carried a gene-editing tool to T cells of the immune system that snipped out their natural T-cell receptors, and then was paired with genes encoding a chimeric antigen receptor, or CAR, a synthetic molecule designed to attack cancer. Next, nanoparticles were targeted to blood stem cells and equipped with mRNA that enabled the stem cells to multiply and replace blood cancer cells with healthy cells when used in bone marrow transplants. Finally, nanoparticles were targeted to CAR T cells and equipped with Foxo1 mRNA, which signals the anticancer T cells to develop into a type of "memory" cell that is more aggressive and destroys tumor cells more effectively and maintains antitumor activity longer.

To Read More: Cell Therapy Can Be Fast and Easy: Just Add mRNA Nanocarriers – Genetic Engineering & Biotechnology News
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Nanoparticles loaded with mRNA give disease-fighting properties to cells – Medical Xpress

By JoanneRUSSELL25

A diagram of a scaffold loaded with CAR T cells and microspheres containing nutrients to help the cells multiply and then leave the scaffold to go attack cancer cells. Credit: Cognition Studio, courtesy of Fred Hutchinson Cancer Research Center. A new biomedical tool using nanoparticles that deliver transient gene changes to targeted cells could make therapies for a variety of diseasesincluding cancer, diabetes and HIVfaster and cheaper to develop, and more customizable.

To Read More: Nanoparticles loaded with mRNA give disease-fighting properties to cells – Medical Xpress
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FDA moves to curb dangerous stem cell clinics – Philly.com

By admin

The U.S.

To Read More: FDA moves to curb dangerous stem cell clinics – Philly.com
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How your own stem cells could relieve your chronic pain – Good4Utah

By Sykes24Tracey

Dr. Khan from Wasatch Pain Solutions gave us insight to Regenexx, the world's most advanced stem cell and blood platelet procedures. On what makesRegenexx treatments better than any other, Dr

To Read More: How your own stem cells could relieve your chronic pain – Good4Utah
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Trendsetter: Why Doug Baldwin went to England for stem-cell therapy – The News Tribune (blog)

By admin

RENTON Turns out, Doug Baldwin started this current Seahawks fad of traveling outside the teams normal medical coverage to get far-flung treatment using body cells. The Seahawks No

To Read More: Trendsetter: Why Doug Baldwin went to England for stem-cell therapy – The News Tribune (blog)
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Bone Marrow Protein May Be Target for Improving Stem Cell Transplants – Penn: Office of University Communications

By NEVAGiles23

Bone marrow contains hematopoetic stem cells, the precursors to every blood cell type. These cells spring into action following bone marrow transplants, bone marrow injury and during systemic infection, creating new blood cells, including immune cells, in a process known as hematopoiesis.

To Read More: Bone Marrow Protein May Be Target for Improving Stem Cell Transplants – Penn: Office of University Communications
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Eliminating the need for bone marrow donors – The Hippocratic Post (blog)

By raymumme

Researchers are looking for ways eliminate the need for bone marrow donors altogether and instead use different types of cells derived from the patient in need of a transplant, says Dr Vladislav Sandler. At the moment, people who develop leukaemia, lymphoma and otherblood diseases often need to undergo a hematopoietic stem cell transplantation (HSCT).

To Read More: Eliminating the need for bone marrow donors – The Hippocratic Post (blog)
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