California Stem Cell Agency Looking for New Home in Two Years
By Dr. Matthew Watson
San Francisco involving the $3 billion California stem cell agency.
science efforts but everything to do with where it is located and its
overhead expenses. The agency will be forced out of its free office
space – 20,000 square feet – in two years. The free space was
provided under an $18 million recruitment package and is worth at
least $1 million a year, according to the agency's auditors.
office-space market is sizzling hot. Google, Yahoo, Microsoft and
other technology firms are scrambling for space in
Baghdad-by-the-Bay, as the city is sometimes known. According to a story this morning by James Temple in the San Francisco Chronicle,
the firms are looking for a total of about 800,000 square feet and
are prepared to pay well for it.
Yahoo would cost about $48 per square foot for a 10-year lease. If
CIRM paid at that rate, it would have nearly $1 million in additional
costs annually. However, leasing rates are expected to rise substantially in the next year or so. Also involved in a move would
be the cost of parking, which could run about $360,000 a year.
examining its options for new offices, including some sort of special
deal with the City of San Francisco.
chairman of the state Democratic Party and co-vice chairman of CIRM,
briefed agency directors on the matter at its meeting in May. He
said,
“I met with the mayor of San
Francisco(Ed Lee), who's a dear friend, and he encouraged us to be
aware that he's very committed to helping us find some space in San
Francisco. Whether it means tax credits or incentives to a potential
landlord, we still have to work that out. Obviously we still have to
work out what the space will be. But the fact that the mayor has
indicated very explicitly that he wants to keep us in San Francisco,
I think it will bode well for us down the road.“The current owner of the property
(Stockbridge Capital Partners) has not been happy that for ten years
they've had to supply free rent to us. And what they didn't
anticipate was having to provide for over $755,000 in operating
costs, which they thought some donors would take are of. Those donors
-- some of whom passed away and others who chose to give money to
other institutions, UC San Francisco, in particular, to the stem cell
lab, which was very much appreciated, I know, by UCSF – but at
the end of the day, there's no room for negotiations with this
current owner.”
Torres whether future rent would also be free. Torres, who is also
president of San Francisco's Public Utilities Commission, replied,
“I would not work on that assumption.
I would work on the assumption somewhere between a dollar and more,
again, dependent upon what kind of tax incentives the City of San
Francisco would provide. We're very fortunate that my son(Joaquin
Torres) is the deputy mayor for economic development, so we also have
him working on this as well.”
“I'll ask more questions offline.”
Hello Doctor Zee 24 Taas Dr Nandini Gokulchandran talks about Stem Cell Therapy Treatments – Video
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BrainStorm's NurOwn Cell Therapy Receives Orphan Drug Designation in the European Union for ALS
By Sykes24Tracey
NEW YORK, NY and PETAH TIKVA, ISRAEL--(Marketwired - Jul 29, 2013) - BrainStorm Cell Therapeutics (OTCQB: BCLI), a leading developer of adult stem cell technologies for neurodegenerative diseases, today announced that the European Commission has granted Orphan Drug Designation for NurOwn, the Company's stem cell therapy consisting of autologous bone marrow-derived mesenchymal stromal cells secreting neurotrophic factors, for the treatment of Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's Disease.NurOwn received Orphan Drug Designation from the Food and Drug Administration (FDA) in 2011.
Orphan drugs benefit from 10 years market exclusivity in the European Union (EU) after marketing approval. Additional benefits for sponsor companies include reduced fees for various centralized activities including applications for marketing authorization, inspections and protocol assistance, as well as possible eligibility for EU grants and other R&D-supporting initiatives.
BrainStorm is currently conducting a Phase IIa dose-escalating trial with 12 ALS patients at the Hadassah Medical Center in Jerusalem, Israel. The company anticipates launching a Phase II multi-center trial at three leading institutions in the United States towards the end of 2013, pending FDA approval.
About BrainStorm Cell Therapeutics, Inc.BrainStorm Cell Therapeutics Inc. is a biotechnology company engaged in the development of first-of-its-kind adult stem cell therapies derived from autologous bone marrow cells for the treatment of neurodegenerative diseases. The Company holds the rights to develop and commercialize its NurOwn technology through an exclusive, worldwide licensing agreement with Ramot, the technology transfer company of Tel Aviv University. For more information, visit the company's website at http://www.brainstorm-cell.com.
Safe Harbor Statement - Statements in this announcement other than historical data and information constitute "forward-looking statements" and involve risks and uncertainties that could cause BrainStorm Cell Therapeutics Inc.'s actual results to differ materially from those stated or implied by such forward-looking statements. Terms and phrases such as "may", "should", "would", "could", "will", "expect", "likely", "believe", "plan", "estimate", "predict", "potential", and similar terms and phrases are intended to identify these forward-looking statements.The potential risks and uncertainties include, without limitation, risks associated with BrainStorm's limited operating history, history of losses; minimal working capital, dependence on its license to Ramot's technology; ability to adequately protect the technology; dependence on key executives and on its scientific consultants; ability to obtain required regulatory approvals; and other factors detailed in BrainStorm's annual report on Form 10-K and quarterly reports on Form 10-Q available at http://www.sec.gov.These factors should be considered carefully, and readers should not place undue reliance on BrainStorm's forward-looking statements.The forward-looking statements contained in this press release are based on the beliefs, expectations and opinions of management as of the date of this press release. We do not assume any obligation to update forward-looking statements to reflect actual results or assumptions if circumstances or management's beliefs, expectations or opinions should change, unless otherwise required by law. Although we believe that the expectations reflected in the forward-looking statements are reasonable, we cannot guarantee future results, levels of activity, performance or achievements.
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BrainStorm's NurOwn Cell Therapy Receives Orphan Drug Designation in the European Union for ALS
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House Speaker Thom Tillis on biotechnology, education and the voter ID bill … – Triangle Business Journal (blog)
By Dr. Matthew Watson
House Speaker Thom Tillis on biotechnology, education and the voter ID bill ... Triangle Business Journal (blog) Despite being at GSK to talk biotechnology growth, he couldn't get away from recent events. And Tillis didn't shy away from criticism of recent Raleigh legislation, such as abortion regulations and the voter ID bill. He defended his party, saying that ... |
Broad-Scale Genome Tinkering With Help of an RNA Guide: Biotechnology Tool … – Science Daily (press release)
By Dr. Matthew Watson
Broad-Scale Genome Tinkering With Help of an RNA Guide: Biotechnology Tool ... Science Daily (press release) July 25, 2013 — Duke researchers have devised a way to quickly and easily target and tinker with any gene in the human genome. The new tool, which builds on an RNA-guided enzyme they borrowed from bacteria, is being made freely available to ... |
HudsonAlpha Institute for Biotechnology, UAB to study childhood genetic … – al.com (blog)
By Dr. Matthew Watson
HudsonAlpha Institute for Biotechnology, UAB to study childhood genetic ... al.com (blog) HUNTSVILLE, Alabama - DNA data from hundreds of North Alabama children and their parents will soon be part of a major new genetic study of childhood diseases led by Huntsville's HudsonAlpha Institute for Biotechnology and including the University of ... |
Wilkes University Professor William Terzaghi of Kingston, Pa., Lectures in China – Wilkes University
By Dr. Matthew Watson
Wilkes University Professor William Terzaghi of Kingston, Pa., Lectures in China Wilkes University Terzaghi flew into Beijing and delivered the first of four lectures on the topic “Studying the Molecular Basis of Hybrid Vigor” and one workshop at the Peking-Yale Joint Center for Plant Molecular Genetics and Agro-Biotechnology, a division of Peking ... |
Thoughts on God’s word (letter) – York Daily Record
By Dr. Matthew Watson
Thoughts on God's word (letter) York Daily Record The essential meaning of this revelation is contradicted by Darwin's hypothesis, which is itself lamentably deficient in evidence, and now contradicted by molecular genetics. Moreover, the symbolism of the image of God in the sexual union of man and ... |
Revealed: how exam results owe more to genes than teaching – Spectator.co.uk
By Dr. Matthew Watson
Spectator.co.uk | Revealed: how exam results owe more to genes than teaching Spectator.co.uk It's no surprise really, to find out towards the end of our conversation that Plomin is not just at the cutting edge of behavioural genetics, but also at the heart of molecular genetics as well. Remember that Chinese programme I mentioned? It turns out ... |
Onslaught of Autism: A Mom’s Crusade Could Help Unravel Scientific Mystery – Jackson Free Press
By Dr. Matthew Watson
Onslaught of Autism: A Mom's Crusade Could Help Unravel Scientific Mystery Jackson Free Press For the majority of patients we know something else is going on, and that might be epigenetic changes," said Emilie Rissman, professor of biochemistry and molecular genetics at the University of Virginia School of Medicine. Many diseases have increased ... |
Party people they are not – The Australian
By Dr. Matthew Watson
Party people they are not The Australian In 2009, at age 19, he received his PhD in molecular genetics and cell biology from the University of Chicago, which then awarded him a MD a year later. But the youngest ever PhD is believed to be Karl Witte, who was awarded a doctorate in philosophy ... |
California Stem Cell Official Duane Roth in Improving Condition
By Dr. Matthew Watson
California stem cell agency, is improving after he was hospitalized
for treatment of a serious brain injury sustained in a bicycle accident Sunday in
the mountains east of San Diego.
Roth's brother, Ted, said yesterday,
“Were certainly moving in the
right direction. We're now looking at the recovery phase.”
has passed through the most critical period following surgery at the
UC San Diego hospital.
Diego technology organization, Connect, is in serious condition in a
medically induced coma.
stem cell agency yesterday took special note of Roth at its meeting and sent its best wishes to him and his family.
Another $23 Million to Recruit Star Stem Cell Scientists to California
By Dr. Matthew Watson
stem cell research stars to the Golden State was expanded today by
another $23 million.
approved the funds on a 14-4-1 vote. CIRM directors Jeff Sheehy and
Francisco Prieto were among those opposing the move. Prieto declared,
“We are coming up against finite resources. We have better ways to spend
our money."
Sheehy said that CIRM is contributing to inflation in stem cell science with its lucrative recruitment grants.
institutions that have not already benefited from one of the earlier
grants in the program. Up to four awards are expected to be made.
said,
“A number of California institutions
have not yet been able to secure a confirmed Research Leadership
award but would benefit greatly from the recruitment of emerging or
established leaders in stem cell biology. Participation in the CIRM
program could bring additional, exceptional researchers to
California, strengthen and synergize with other efforts to build up
local sustained research communities in stem cell biology and
medicine and provide ongoing leadership at the cutting edge of
California regenerative medicine.”
involved with the winning researchers have representatives on the
governing board of the stem cell agency. They are not allowed, however, to vote
on grants to their institutions or researchers -- only on proposals such as today's $23 expansion.
final approval scheduled for next May. The program is not open to
businesses.
California Stem Cell Agency Launches $70 Million Alpha Stem Cell Clinic Project
By Dr. Matthew Watson
The California stem cell agency today approved
a $70 million plan to create a network of “Alpha” stem cell
clinics that is aimed at making the Golden State one of the leading
purveyors and developers of stem cell therapies in the world.
Institute for Regenerative Medicine (CIRM)adopted the plan on a 19-1 vote. The negative vote came from Joan Samuelson, who questioned
whether the plan was premature and whether existing scientific research justified development of the clinics.
former head of a Hollywood studio, said the proposal is “one of the
most exciting proposals that we have ever had in front of us.” She
said it was the “beginning of this dream coming true.”
CIRM President Alan Trounson has been promoting for two years, the
agency will finance five stem cell clinics at established
institutions in California with grants of up to $11 million. Another
$15 million will be allotted for a stem cell information and
coordination center. Major matching contributions will be expected
from award winners over the five-year terms of the grants.
clinical trials and patients from the around the world and creating a
central bank of knowledge, know-how and regulatory expertise. It
will also guide efforts to build profits into stem cell therapies
and to develop strategies to attract investors and philanthropists.
(For more information on the plan, see here, here, here, here and
here.)
“These clinics have the potential to
revolutionize how we deliver stem cell therapies to patients. Stem
cell therapies are a completely new way of treating diseases and
disorders so we need a completely new way of delivering those in a
safe and effective manner. These clinics will help us do just that
and the clinical trials carried out in this network will fulfill the
agency’s promise of bringing new therapies to patients who need
them.”
reported that the Alpha clinics would be the first-ever “clinical
trials network focused around a broad therapeutic platform.”
comment on the plan other than the remarks by Samuelson. . However,
not everyone sees a need for it. Mahendra Rao, director of the Center
for Regenerative Medicine at the National Institutes of
Health(NIH) , says its surveys of researchers have not shown a demand
for such centers. In May, a researcher at institution that likely
would be an applicant filed a blistering, anonymous comment on the
California Stem Cell Report, describing it as a "boondoggle" and "irresponsible." The scientist said,
“Another boondoggle for some medical
schools but made to order for private operators like for-profit
cancer, dialysis, and laser eye specialty clinics that do one
procedure. I can see each of the medical schools gifted with
one as they each were gifted with about 25 million dollars for stem
cell institute buildings.”
“The NIH at various times has tried
to organize clinical trials groups with infrastructure, like quick
reaction forces, ready to gear up for a new trial at the drop of a
hat. They mainly did nothing but suck money, kept staff employed,
because there are generally few drugs ready for early human trials
and each treatment that is brought along requires a unique contract,
ethics reviews, and different facilities, equipment and staff than
planned for. The latest incarnation are CTSAs or CTSIs,
clinical and translational science centers funded by the federal NIH
that most if not all California medical schools already have.”
go out in October and approval of funding coming one year from now. Here is the link to today's CIRM press release on the plan.
Source:
http://feedproxy.google.com/~r/blogspot/uqpFc/~3/EBbBzLL9dQQ/california-stem-cell-launches-70.html
Coming Up: Live Coverage of Today’s California Stem Cell Meeting
By Dr. Matthew Watson
provide live, wall-to-wall coverage of today's meeting of the
governing board of the $3 billion California stem cell agency.
million proposal aimed at creating a string of Alpha stem cell clinics in
California that would serve as a foundation for the state's stem cell
business. Also on tap are other proposed grant programs, including a
$23 million expansion of a researcher recruitment effort and a $35 million round aimed at removing roadblocks to turning research into
cures.
throughout the day based on the Internet audiocast of the proceedings.
on the meeting via the Internet. Instructions can be found on the agenda.
Source:
http://feedproxy.google.com/~r/blogspot/uqpFc/~3/Vi8IGlL2TzY/coming-up-live-coverage-of-todays.html