SAN DIEGO, March 08, 2023 (GLOBE NEWSWIRE) -- TRACON Pharmaceuticals, Inc. (Nasdaq: TCON), a clinical stage biopharmaceutical company utilizing a cost-efficient, CRO-independent product development platform to advance its pipeline of novel targeted cancer therapeutics and to partner with other life science companies, today announced financial results for the fourth quarter and year ended December 31, 2022. The Company will host a conference call and webcast today at 4:30 PM Eastern Time / 1:30 PM Pacific Time.

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TRACON Pharmaceuticals Reports Fourth Quarter and Year-End 2022 Financial Results and Provides Corporate Update

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SAN DIEGO, March 08, 2023 (GLOBE NEWSWIRE) -- Viracta Therapeutics, Inc. (Nasdaq: VIRX), a precision oncology company focused on the treatment and prevention of virus-associated cancers that impact patients worldwide, today announced that Mark Rothera, its President and Chief Executive Officer, and Lisa Rojkjaer, M.D., its Chief Medical Officer, are scheduled to participate in a virtual fireside chat at the 33rd Annual Oppenheimer Healthcare Conference on Wednesday, March 15, 2023, at 12:00 p.m. ET.

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Viracta Therapeutics to Present at the 33rd Annual Oppenheimer Healthcare Conference

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ROCKVILLE, Md., March 08, 2023 (GLOBE NEWSWIRE) -- Supernus Pharmaceuticals, Inc. (Nasdaq: SUPN), a biopharmaceutical company focused on developing and commercializing products for the treatment of central nervous system (CNS) diseases, announced today that the Supernus Pharmaceuticals management team will participate in the following March investor conferences:

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SAN FRANCISCO, March 08, 2023 (GLOBE NEWSWIRE) -- Vir Biotechnology, Inc. (Nasdaq: VIR) today announced that Phil Pang, M.D., Ph.D., Executive Vice President, Chief Medical Officer and Interim Head of Research, is scheduled to present at the Barclays Global Healthcare Conference on Wednesday, March 15, at 7:15 a.m. PT / 10:15 a.m. ET.

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Conference call to begin at 4:30 p.m. ET

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Vaxart to Host Full Year 2022 Business Update and Financial Results Conference Call on March 15

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REDWOOD CITY, Calif., March 08, 2023 (GLOBE NEWSWIRE) -- Jasper Therapeutics, Inc. (Nasdaq: JSPR) (Jasper), a biotechnology company focused on development of briquilimab, a novel antibody therapy targeting c-Kit (CD117) to address diseases such as chronic spontaneous urticaria, lower to intermediate risk myelodysplastic syndromes (MDS) as well as novel stem cell transplant conditioning regimes, today announced results for the fiscal year ended December 31, 2022, and provided a business update.

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Jasper Therapeutics Reports Fiscal 2022 Financial Results and Provides a Business Update

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Webcast set for 7:30 a.m. ET on March 9 Webcast set for 7:30 a.m. ET on March 9

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Clene to Announce New CNM-Au8® Data From the Healey ALS Platform Trial

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Full-Year Net Revenue of $10 Million and Fourth Quarter Net Revenue of $2.6 Million

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Nephros Announces Fourth Quarter and Fiscal Year 2022 Financial Results

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NEW YORK, March 08, 2023 (GLOBE NEWSWIRE) -- Cellectis (the “Company”) (Euronext Growth: ALCLS - NASDAQ: CLLS), a clinical-stage biotechnology company using its pioneering gene-editing platform to develop life-saving cell and gene therapies, today provided a business update and announced its results for the fourth quarter of 2022, and full year ending December 31, 2022.

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Cellectis Provides Business Update and Reports Fourth Quarter and Full Year 2022 Financial Results

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NEWS RELEASE – REGULATED INFORMATIONMARCH 8, 2023, 5:00 pm ET/ 23:00 CET

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MDxHealth Announces Update of Outstanding Shares and Voting Rights

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TORONTO and CHICAGO, March 08, 2023 (GLOBE NEWSWIRE) -- Medexus Pharmaceuticals (TSX: MDP; TSX: MDP.DB; OTCQX: MEDXF) today entered into a new senior secured credit agreement agented by BMO. The credit agreement provides for a US$35 million term loan facility and a US$3.5 million revolving loan facility for working capital. The term loan facility benefits from an additional US$20 million uncommitted accordion feature, which Medexus is confident will be available. The new BMO facilities will mature in March 2026, being three years from the date of the credit agreement.

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Medexus Announces US$58.5 million in New Credit Facilities

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SEATTLE, March 08, 2023 (GLOBE NEWSWIRE) -- Neoleukin Therapeutics, Inc., “Neoleukin” (NASDAQ:NLTX), a biopharmaceutical company utilizing sophisticated computational methods to design de novo protein therapeutics, today announced that it has engaged SVB Securities to assist in reviewing strategic alternatives for the Company with the goal of maximizing shareholder value. Such alternatives may include a sale, merger, divestiture of assets, licensing or other strategic transaction. There can be no assurance that the exploration of strategic alternatives will result in any agreements or transactions, or that, if completed, any agreements or transactions will be successful or on attractive terms. Neoleukin does not expect to disclose or provide an update concerning developments related to this process until the Company enters into definitive agreements or arrangements with respect to a transaction or otherwise determines that other disclosure is necessary or appropriate.

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Neoleukin Therapeutics Provides Strategic Update and Announces Restructuring and Leadership Transition

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– Nirogacestat Treatment Significantly Improved Progression-Free Survival, Objective Response Rate and Key Patient Reported Outcomes –

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SpringWorks Therapeutics Announces New England Journal of Medicine Publication of Phase 3 DeFi Trial Evaluating Nirogacestat in Adults with Desmoid...

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TORONTO, Ontario and CAMBRIDGE, Massachusetts, March 08, 2023 (GLOBE NEWSWIRE) -- ProMIS Neurosciences Inc. (TSX: PMN) (Nasdaq: PMN), a biotechnology company focused on the generation and development of antibody therapeutics targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA), today announced its full year 2022 financial results and recent highlights.

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ASHBURN, Va., March 08, 2023 (GLOBE NEWSWIRE) -- Quoin Pharmaceuticals Ltd. (NASDAQ: QNRX) (the “Company” or “Quoin”), a clinical stage, specialty pharmaceutical company focused on rare and orphan diseases, today provides a business update and announces financial results for the fourth quarter and full year of 2022.

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Quoin Pharmaceuticals Provides Corporate Update and Announces Fourth Quarter and Full Year 2022 Financial Results

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ROCKVILLE, MD, March 08, 2023 (GLOBE NEWSWIRE) --  MacroGenics, Inc. (Nasdaq: MGNX), a biopharmaceutical company focused on developing and commercializing innovative monoclonal antibody-based therapeutics for the treatment of cancer, today announced that it has entered into an agreement to sell its royalty interest on future global net sales of TZIELD (teplizumab-mzwv) to a wholly-owned subsidiary of DRI Healthcare Trust for up to $200 million. MacroGenics retains its other economic interests related to TZIELD, including future potential regulatory and commercial milestones.

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MacroGenics Announces Sale of TZIELD™ Royalty Interest for up to $200 Million

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ADELAIDE, Australia, March 08, 2023 (GLOBE NEWSWIRE) -- Bionomics Limited (Nasdaq: BNOX | ASX: BNO) (Bionomics or Company), a clinical-stage biopharmaceutical company developing novel allosteric ion channel modulators for serious central nervous system (CNS) disorders with high unmet medical need, today announced the release of a comprehensive analysis of the data from its Phase 2 PREVAIL study to evaluate the efficacy and safety of BNC210, a novel ?7 nicotinic acetylcholine receptor negative allosteric modulator, for the acute treatment of Social Anxiety Disorder (SAD). These data support late-stage development of BNC210 in SAD.

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Bionomics Reports Promising Full Results Analysis from PREVAIL Phase 2 Study of BNC210 Social Anxiety Disorder (SAD)

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The body is always in a state of change. In particular, the cells in your skin are constantly replacing themselves.

The skin does this through the process of regeneration and repair.

On a cellular level, the skin cells are constantly shedding, revealing fresh, newly grown skin cells underneath. This is why scars and blemishes may fade a bit with time.

Understanding the science behind your skins life cycle can help you to take care of your skin as it goes through the regeneration process. It can also help you boost your skins natural regeneration process and give you a fresh glow.

Heres what the skin care experts have to say about how to speed up skin regeneration.

According to 2015 research, skin regeneration refers to the complete replacement of damaged tissue with new tissue. Skin repair refers to the continued healing process of existing tissue. Skin regeneration isnt usually associated with scar tissue.

The research goes on to say that skin regeneration can happen in two ways:

Skin regeneration is a natural physical process that occurs on a cellular level.

The epidermis cells, or top layers of skin, continuously replace themselves, explains Laura Chacon-Garbato, a licensed esthetician and director of education at Herbalife. This process of renewal is the process of shedding the epidermis.

In other words, skin regeneration is a constant renewal of cells.

According to a 2010 review, the epidermis is maintained by stem cells in the lowest layer of the skin. These epidermal stem cells generate daughter cells that move upward toward the surface of the skin.

During this journey, cells that produce keratin undergo a series of biochemical and morphological changes that result in the formation of the various layers of the skin.

This gives skin a young, healthy glow, adds Jennifer Hurtikant, chief science officer at Prime Matter Labs.

The same study mentioned above estimated that the epidermis turns over every 40 to 56 days on average.

When were young, the process of exfoliation happens naturally, but as we age this process is altered and slows down, Chacon-Garbato says.

An older 2006 study notes that the usual 28-day turnover time for skin increases approximately 30 percent to 50 percent by age 80.

For people over 50 years old, Chacon-Garbato says, the process can take as long as 84 days.

The effects of the slowdown cause buildup and an excess of dead skin cells that can make the skin look tired, dull, and opaque, she says.

Throughout this process, several things occur on a cellular level.

First, new skin cells are formed deep in the epidermis.

Then, as the skin cells mature and die on the upper layer of the epidermis, they naturally fall away.

If you have a cut or burn, you may be left with a scar.

This is because fibroblasts in scar tissue form collagen differently than in regular tissue. As a result, its thicker and less flexible than regular skin tissue.

However, by improving skin regeneration, you may notice that scars gradually fade away as fresh, healthy skin tissue forms beneath them.

As you get older, skin regeneration slows down. This leaves an accumulation of dead skin cells on the upper layer of the skin.

By boosting the natural regeneration process, you can help the skin look fresh and feel elastic, even as you age.

Making healthy choices can help to keep the skin regeneration process functioning optimally.

Hurtikant suggests:

There are two types of aging, cellular or intrinsic aging and environmental or extrinsic aging.

Intrinsic aging is a genetically predetermined process that occurs naturally, but may increase with stress. Extrinsic aging is a result of outside factors, like where you live and your lifestyle habits.

Stress causes intrinsic aging and the environment causes extrinsic aging, Hurtikant says.

Chacon-Garbato recommends eating plenty of protein, such as:

Proteins are essential for tissue repair and the construction of new tissue, she says. Cells need protein to maintain their life, so the body uses protein to replace worn-out or dead skin cells.

In addition, favor foods that are high in antioxidants, like:

Including antioxidants in your diet may help improve the glow and luster of the skin.

Specific skin care products can also help improve the natural cell turnover process, hydrate the skin, and get rid of built-up dead skin cells. Look for ingredients like:

Use products with vitamin B3, Chacon-Garbato suggests. Its a necessary component of cell metabolism, also known as niacinamide, and is required for many skin processes that help maintain healthy-looking skin.

She also suggests using antioxidants such as vitamin C and E to prevent cellular damage from free radicals.

Try Swisse Beauty Skin Regeneration+, an oral supplement with ALA, and Musely FaceRx Anti-Aging Night Cream with tretinoin, hyaluronic acid, and niacinamide.

These natural remedies may help boost your skins health and promote the skin regeneration process:

A 2022 study found that several plant extracts, including papaya, showed antioxidant, and antiwrinkle effects. Extracts that used ethanol as a cosolvent showed greater effects.

A 2018 review found that jojoba, rosehip, and coconut oil may help with skin barrier repair, wound healing, antioxidant effects, and antiaging.

A 2010 study noted that orange peel extract could provide useful protection against or alleviation of UV damage.

You can look for natural skin care products that contain these ingredients.

Citrus can increase photosensitivity, or sensitivity to light. Use caution when applying citrus in any form to the skin by avoiding direct sun exposure and using sun protection. Never apply citrus oils directly to the skin.

If you want to exfoliate a little deeper, a dermatologist may be able to offer a more intensive skin resurfacing procedure to kick-start skin rejuvenation. Make sure you find a dermatologist who is board certified.

Chacon-Garbato suggests:

However, she notes, theres no one-size-fits-all for the skin, so its important to check with your dermatologist to help define the best approach for the results you want to achieve.

Want to know more? Get the FAQs below.

Aloe vera encourages cell diversity and helps keep the skin well hydrated and protected.

According to a 2020 study, it also boasts natural antioxidant and anti-inflammatory properties.

Aloe vera is an excellent ingredient to use daily because its well known for its revitalizing and calming properties, Chacon-Garbato says. Its also a hugely effective hydrator and helps to minimize skin dryness.

She notes that its been used for centuries for beauty because of its many benefits, including delivering moisture directly to the tissue and helping prevent water loss due to evaporation.

Hurtikant adds that while aloe vera is great for boosting regeneration, there are other ingredients to try too.

Trending ingredients for skin regeneration are derivatives of algae and mushrooms, and hyaluronic acid, she says.

There are plenty of skin care products that have been shown to improve the appearance of aging in the skin by speeding up the natural skin regeneration process.

One highly rated product is Musely FaceRx Anti-Aging Night Cream, which includes active ingredients such as tretinoin (Retin-A), niacinamide, and hyaluronic acid.

These three ingredients are all excellent for encouraging exfoliation. Keep an eye out for them on the ingredients list when youre looking for good creams to promote regeneration.

For most adults under 50 years old, the cycle lasts between 28 and 42 days. For adults over 50 years old, this may increase to up to 84 days, though the number varies.

The time it takes for your skin to complete the skin regeneration cycle depends on a range of factors, including:

There are a range of ways to improve skin regeneration.

Simple lifestyle changes like exercise and increased hydration can keep the process working properly.

Skin creams that include exfoliating ingredients can also help to get rid of excess dead skin.

Some procedures can also encourage faster growth of new skin cells to speed up the regeneration process.

Aging slows down the skin regeneration process, but it doesnt ever stop it completely.

However, because the process becomes much slower as we age, the skin can appear thicker, less flexible, and more wrinkled or textured.

This is because the slower the regeneration, the more dead skin cells remain on the face.

Skin regeneration is a natural cycle that occurs as the skin cells turn over. In other words, dead skin cells on the top layer of the epidermis fall away, revealing fresh, newly created cells beneath.

By supporting this cycle with a healthy lifestyle and skin care routine, you can encourage a lustrous glow even as you get older.

Just remember: while boosting skin regeneration is possible, its natural for the cycle to slow down as you age. A few wrinkles and some texture are nothing to be ashamed of.

You can even think of them as signs of wisdom and experience.

Meg is a freelance journalist and features writer who covers culture, entertainment, lifestyle and health. Her writing has appeared in Cosmopolitan, Shondaland, Healthline, HelloGiggles, Readers Digest, Apartment Therapy, and more. T: @wordsbyMeg W: megwalters.co.uk

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Skin Regeneration: The Science and How to Boost It - Healthline

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NGM BIOPHARMACEUTICALS INC Management's Discussion and Analysis of Financial Condition and Results of Operations. (form 10-K)  Marketscreener.com

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NGM BIOPHARMACEUTICALS INC Management's Discussion and Analysis of Financial Condition and Results of Operations. (form 10-K) - Marketscreener.com

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Treat Yourself to a Spa Day With a $100 Deal on $600 Worth of Products From Elemis, U Beauty, Nest & More  E! NEWS

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Treat Yourself to a Spa Day With a $100 Deal on $600 Worth of Products From Elemis, U Beauty, Nest & More - E! NEWS

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