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Stem Cell Therapy in California Covered by Insurance (888) 828-4575 – Video
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Stem Cell Therapy in California Covered by Insurance (888) 828-4575
http://stemcelltherapyincalifornia.com TeleHealth offers stem cell therapy for arthritis, tendonitis, ligament injuries that is covered by insurance. This in...
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Stem Cell Therapy in California Covered by Insurance (888) 828-4575 - Video
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September 16th, 2013
Genetic engineering helps damaged heart cells beat again – DVICE
By Dr. Matthew Watson
 DVICE | Genetic engineering helps damaged heart cells beat again DVICE Although heart disease is the leading cause of death in the United States, there are now more than 5 million heart attack survivors in the country. Due to the amount of heart cells that are damaged during an attack and the resulting scar tissue that ... |
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September 1st, 2013
Newborns Could Soon Be Screened for Rare Pompe Enzyme Deficiency Disorder
By Dr. Matthew Watson
Shortly after a baby’s first wail at birth she or he receives a tiny prick on the heel. A few drops of blood are caught on special filter paper to screen for myriad diseases. [More]
-- Read more on ScientificAmerican.com
http://rss.sciam.com/~r/sciam/topic/gene-therapy/~3/qJICV6zfIAo/article.cfm
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September 1st, 2013
Tracking the Fruits of California Stem Cell Agency Research
By Dr. Matthew Watson
cell agency yesterday shed some interesting light on the awards in its $41
million round this week and their pathway to actually producing a product that
can be used to treat persons who are suffering from diseases.
long journey to generate usable therapies, a process poorly understood by the
public, which was promised in 2004 that the stem cell agency would produce
cures for ailments afflicting half the population of the state.
She said,
“Many scientists who
receive our early translation awards first got their idea for a therapy while
carrying out research with one of our other awards. In fact, eight of the
scientists in this round of funding had previous CIRM funding for an earlier
stage of research. If a scientist's early translation award provides good
results, the scientists are then able to apply for one of our disease team
awards, which fund the effort of compiling data to convince the Food and Drug
Administration to allow them to test it in people. Other organizations
fund only early discovery research or only preclinical research. Under those
conditions, researchers continually pause their projects to look for new
sources of funding as the project moves through the phases toward clinical
trial.”
the California stem cell agency is its promise of a continued stream of
funding. Former Chairman Robert Klein used to tout that particular aspect of
the agency, particularly in light of limited federal resources.
implicitly raise important questions concerning CIRM’s entire portfolio. How
many CIRM grants have led to additional funding from CIRM? How many are
basically one-off shots that have not led to research that has advanced the
development of stem cell therapies, either via CIRM or other funding. What is the
therapeutic and scientific significance of the research that is linked by more
than one CIRM award? What previously
funded CIRM research could be fruitfully funded again to advance the science
and not necessarily through the traditional grant rounds, which sometimes have
awkward timing?
item is an application from a UC Irvine researcher that came up at Wednesday’s
meeting of the governing board of the stem cell agency. The woman, whose name
was not clearly audible on the Internet audiocast, publicly appealed rejection
of her application by reviewers. She noted that it was an extension of work
that was previously funded by the agency. She also noted that the score on her
review was all but identical to work that was funded. The board, however,
turned her appeal aside, which had already been rejected behind closed doors by
CIRM staff.
such case in CIRM history. But they are virtually impossible to track systematically
because of the structure of the CIRM grant-making progress. It is also not
clear whether the agency itself is tracking its research awards to determine if
they result in continuing, fruitful research in a specific area. Nonetheless,
the matter deserves some public attention.
Source:Stem Cell Therapy
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September 1st, 2013
UCLA Snags $3.6 Million from California Stem Cell Agency
By Dr. Matthew Watson
UCLA scored today with at least two grants, totaling $3.6 million, from the California stem cell agency.
Seeking the cash were Donald Kohn, application 6823, and Gerald Lipshutz, application 6831. Both of the grants are for $1.8 million each.
Source:Stem Cell Therapy
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September 1st, 2013
Stem Cell Agency Seeks Stronger Ties with Possible Industry Funding Partners
By Dr. Matthew Watson
The California stem cell agency today triggered a new program aimed at recruiting major biotech and venture capital firms to assist in providing tens of millions of dollars for research by California enterprises.
The effort, part of an $80 million business-friendly initiative, was approved by the agency's governing board on a voice vote.
Source:Stem Cell Therapy
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September 1st, 2013
UCLA Takes Four of 13 Awards Today; One Business Wins
By Dr. Matthew Watson
The California stem cell agency has
made it official, sending out its press release on the $41 million in grants
approved today for institutions throughout the state.
the agency. Individual board members, however, are barred from voting on specific grants
to their organizations.
institution received more than one, including only one business, Numerate, Inc., of San Bruno,
via John
Griffin, the firm's chief scientific officer. The lack of awards
to businesses has long been a sore subject in the biotech community.
identified one of the five researchers who lost their appeals on negative grant
review decisions. He is Evan
Snyder, leader of stem cell research at Sanford-Burnham Medical Research
Institute in La Jolla, who
had a $5 million request before the agency.
Source:Stem Cell Therapy
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September 1st, 2013
$41 Million in California Stem Cell Grants Virtually Approved
By Dr. Matthew Watson
Directors of the California stem cell agency today all but approved about $41 million in early translational grants, rejecting all appeals by applicants and accepting staff recommendations on marginal grants.
The roll call vote was held open this morning to record a vote by one board member who was not present at the time. It is virtually certain that the member will vote in favor of affirmative action on the applications in question.
One member of the board, Joan Samuelson, abstained from voting on any of the applications. She said she did not think the board had adequate information on its total grant portfolio, particularly in view of the declining amount of money available.
The agency has about $600 million in uncommitted funds and is scheduled to run out of cash for new grants in 2017.
The research acted on today is aimed at “proof of concept for development of a therapy candidate and/or studies to select a development candidate. The approved grants can be found on this CIRM website page and are listed in tier one and tier two. Identities of the applicants are withheld by CIRM to avoid embarrassing rejected candidates and to avoid disclosing the names of applicants to board members before they vote. However, applicants often appear before the board, as they did today, and identify themselves.
Five applicants appealed negative decisions on their applications by grant reviewers. The agency declined to disclose the appeal letters or identify the applicants, information that was a public record under the previous appeal procedures. New processes were put in place this spring that moved the appeals behind closed doors and made them subject to staff instead of board review. Nonetheless, rejected researchers have a legal right to address the board on appeals or any other matters.
At the request of the California Stem Cell Report, the agency provided the numbers of the grants on which appeals were filed. They are: 06787, 06888, 06761, 06793 and 06830. Review summaries on the applications can be found here.
We have asked the agency to provide its legal and policy justification for now withholding information that was once a public record.
http://feedproxy.google.com/~r/blogspot/uqpFc/~3/QDuPoOEt0Xc/41-million-in-california-stem-cell.html
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September 1st, 2013
Stem Cell Agency Pays Tribute to the Late Duane Roth
By Dr. Matthew Watson
The governing board of the California stem cell agency today paid tribute to the late Duane Roth, co- vice chairman of the agency, who died recently as the result of a bicycle accident.
With members of Roth's family present, CIRM Chairman J.T. Thomas characterized Roth, 63, as a "voice of reason" on the 29-member board. The video included testimonials from both staff and board members.
He was described as a "kind person" who could find "common ground" on difficult issues. Roth was deeply involved in San Diego affairs that went well beyond the stem cell agency. More than 1,000 persons attended memorial services for Roth earlier this month in San Diego.
CIRM President Alan Trounson said following the video that he will "miss (Roth) terribly" and expressed "hope that his memory will lighten and brighten the day for all of us."
Jeanne Loring, a stem cell researcher at Scripps, said Roth "inspired us to do more than we thought we could do." She said he was an unusual kind of businessman who respected science. "I wish I could thank him one more time," she said.
http://feedproxy.google.com/~r/blogspot/uqpFc/~3/Oq2mWojUfsQ/stem-cell-agency-pays-tribute-to-late.html
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September 1st, 2013
Skin in California’s Stem Cell Game
By Dr. Matthew Watson
financial future makes a big, $200 million assumption.
public-private partnership to continue with the agency’s work after 2017, when
its cash basically runs out.
assumptions for development of the proposed partnership, which is now in the very early stages of being crafted by a Marin County consultant, James Gollub.
He was told that whatever he comes up with can assume a onetime, $50 million to
$200 million public contribution.
the 1940s -- is how to raise that sort of cash. Consider two unappetizing possibilities.
The 29 members of the agency’s governing board could go to Sacramento and ask
lawmakers and the governor to give them the money, a prospect that most of them
would not relish. Such a move would open the door to tinkering or more with the
agency’s structure and operations. Or
the board could seek more bond financing via a statewide election, requiring an
electoral campaign that would cost many millions to mount. In both cases, there
is no guarantee that funds would be forthcoming. Money is still tight in
California government, and voters may not fancy spending more on stem cell
research, especially if the agency has not delivered on the promises of the
2004 ballot campaign that created the $3 billion program.
be difficult considering pressures to spend all that the agency has. The
board of the California Institute for Regenerative Medicine (CIRM), as the agency
is formally known, has about $600 million in uncommitted cash. It could take
$200 million off the table and reserve it as seed money for whatever future
plans would involve. Or the board could simply roll back commitments it has
made for lower priority grant rounds – ones that have not yet been initiated.
Some are in concept stages, and others have not yet been posted as RFAs.
the condition of all board members. The question of priorities on spending came
up last month in connection with the agency’s generous, $69 million researcher
recruitment effort that benefits many institutions represented on the agency’s
board. Jeff Sheehy, who is a patient advocate member of the board but also a
communications manager at UC San Francisco, and others bridled at adding more money to the
recruitment program. Sheehy cited scarcity of funds and said it was a “distraction”
from more important efforts. His view, however, did not prevail.
totaling only $37 million. Board members, if they wish, could indicate that the
surplus $33 million be designated as a down payment on the future of the agency
– an organization in which they take great pride.
http://feedproxy.google.com/~r/blogspot/uqpFc/~3/H4C5-MLOao4/skin-in-californias-stem-cell-game.html
Still Time to Register for International Biotechnology Symposium Aug. 26 – Hoosier Ag Today
By Dr. Matthew Watson
 Hoosier Ag Today | Still Time to Register for International Biotechnology Symposium Aug. 26 Hoosier Ag Today ibs_logo Fortunately, U.S. and international biotechnology companies will have dozens of new transgenic events that increase crop yields and quality ready for registration by 2015. Unfortunately, the world is lacking a synchronized, science-based ... |
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August 25th, 2013
California Stem Cell Agency’s $150,000 Search for Its Financial Future
By Dr. Matthew Watson
often known as an “economic therapist,” has been selected to
devise a “strategic road map” for the financial future of the $3
billion California stem cell agency.
 |
| James Gollub: 'economic therapist' Gollub Associates photo |
firm bearing his name, is under a $150,000 contract to lay out by
this fall a detailed plan for the agency. The nine-year-old research
effort is scheduled to run out of money for new awards in 2017.
posted a request for proposals (RFP) last spring. The RFP assumed an
additional $50 million to $200 million in a onetime “public
investment.” The RFP also assumed additional private funding of a
yet-to-be-determined nature.
is known as an “economic therapist.” The website for his current firm says,
“A leading expert in innovation
bridge building....
“Global experience assisting
universities, institutes, government agencies and public-private
partnerships link innovation sources to innovation
seekers.
“Committed to the goal of increasing flow of needed
solutions, optimizing financial returns and sustainable economic
impacts from innovation.”
March of this year. His Linked In profile says,
“James Gollub Associates
(JGA) LLC was launched to build on 36 years of Gollub’s
professional research and consulting experience. That experience
began with 16 years at SRI International, three years at
DRI/McGraw-Hill, five years at IDeA, nine years at ICF International
and three years with E-Cubed Ventures LLC. During that
time Gollub has worked globally to deliver
economic strategies for over 30 national, state and metropolitan
regions, develop strategies to accelerate growth of new industries
(clusters), plan public and private R&D institutes and advise on
over 15 science and technology parks.”
The need for a financial transition plan for CIRM was publicly identified as long ago as 2009 by the Little Hoover Commission in its lengthy study and has been reiterated periodically by other bodies since then. Under the terms of Prop. 71, which created the agency, CIRM has only a 10-year authority to issue state bonds, the borrowed funds that have sustained the research effort. Legal maneuvering blocked the issuance of bonds until 2007.
The California Stem Cell Report asked
the stem cell agency on May 31 for a copy of Gollub's response to the
RFP. Yesterday we asked for a copy of the contract with Gollub. Those
documents will be published when they are received.
http://feedproxy.google.com/~r/blogspot/uqpFc/~3/tncFJBJJM5I/california-stem-cell-agencys-150000.html
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August 25th, 2013
California Stem Cell Researchers to Receive $70 Million Next Week
By Dr. Matthew Watson
scheduled to give away $70 million next week as it moves forward on
its efforts to turn research into cures.
projected to be awarded in the early translation round. The awards will range up to $3.5 million over a three year period. The round was open to
both businesses and academic institutions. Collaborators from Germany
were involved, although funding for research in that country is not provided by the state stem cell agency.
the $3 billion agency's governing board at its Aug. 28 meeting in La Jolla. After next week's awards, the agency, which is known as CIRM, will have about $500
million left to hand out before cash for new awards runs out in 2017.
The agency is currently examining ways to continue its awards with
some sort of public-private partnership.
proposed announcement for a CIRM/industry co-funding agreement. No
further details on that program were available early today on the agenda.
Other matters to be considered include final approval of the changes
in the agency's IP regulations, appointment of new members to the
grant review group and the latest report on the outside contracts
held by the agency. Details on those matters are yet to be posted by
the agency.
co-vice chairman of the agency, is also scheduled. The board will
additionally meet behind closed doors to evaluate the performance of
CIRM President Alan Trounson.
carry more information on the meeting as it becomes available.
for the meeting, other locations where the public can take part in
the meeting are in Menlo Park and Duarte. Specific addresses can be
found on the agenda.
Source:Stem Cell Therapy
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August 25th, 2013
Flim-Flam Stem Cell Artists Targeted by CIRM
By Dr. Matthew Watson
joined with other prestigious stem cell organizations to help put a
stop to the flim-flam artists that prey on desperate people by
promising miracle cures from stem cell treatments.
patients should consider when making treatment decisions.”
education communications officer and author of the blog item, said
the document addresses one of his special concerns: Internet “ads
that come up on web searches and seem to be offering everything to
everyone.”
automatically by Google.
Source:California Stem Cell Agency Spending: Where the Money Is Going
By Dr. Matthew Watson
 |
| Analysis of CIRM funding by Pat Olson, executive director of CIRM scientific activities July 2013 |
have committed $472 million to translational research – a key to
commercializing stem cell therapies – if it awards the full $70
million in new grants and loans slated to come before its governing
board next week.
about 17 percent of its funding so far, according to an analysis last
month by Pat Olson, the agency's executive director of scientific activities. The
largest percentage of the agency's cash, however, will be going for
“development” – 35 percent or $970 million. Olson defined
“development” as “essentially our IND enabling, our
preclinical development programs and our clinical development
programs.”
or about $469 million with buildings and facilities taking up $443
million or 16 percent. Training and career development has consumed
about 15 percent or $414 million.
$577 million in funds that have been allocated but not yet awarded.
Another $491 million is “concept approved” but also not awarded.
The agency's governing board could change those allocations or
withdraw approval of concepts, although it has not yet shown signs
that it might do so.
new grants in 2017 and is examining the possibility of generating
more cash through some sort of public-private partnership. To develop
support for continued funding, the agency is under pressure to
generate results that will resonate with the public and potential
private funding sources. Those results are most likely to come from
a late stage translational/clinical trial effort.
(An earlier version of this item incorrectly said that the agency would run out of money for new grants in 2013. The correct year is 2017,.)
Source:Stem Cell Therapy
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August 25th, 2013
A $2 Million Bill: Outside Contracting by California Stem Cell Agency
By Dr. Matthew Watson
agency this week posted a list of its outside contractors, who range
from a a $25,000 stem cell licensing consultant to a $550,000-a-year law firm.
million during 2013-14 on outside contracting, down from $2.9 million
in 2012-13. This week's report covers the 2012-13 year.
largest item in the agency's budget, which is slated to spend $17.4
million this fiscal year for operational expenses, up 5 percent
from last year's spending. The largest amount, $12.2 million, goes
for salaries and benefits. (For more on the budget, see here, here
and here.)
firm of Remcho, Johansen & Purcell of San Leandro, Ca., which had
the $550,000 contract. CIRM, as the agency is known, reported that Remcho came in under
budget by $95,595. That contrasts to some previous years when the
firm, which has represented the stem cell agency since its inception,
required additional cash on top of its original contract. James
Harrison of the Remcho firm is its face at the agency and is
designated as the outside counsel to the agency's governing board. In
all, the agency is slated to spend $2.2 million on legal expenses,
including in-house work.
contractor. He was paid only $13,125 on his $25,000 contract during
2012-13. It is unclear whether he will be paid the $11,875 balance.
Earp was chief patent counsel and senior vice president for business
development for Geron before it dropped its stem cell program. Earp was heavily involved in the $25 million loan that CIRM made to Geron in 2011. In
February 2008, he testified before CIRM about its then proposed loan
program.
$200,000 to the AlphaMed Press of Durham, N.C., as seed funding for a
stem cells translational journal, $156,434 to Hyatt Hotels for the
meeting of CIRM grant recipients, $250,000 to Kutir Corp. of Newark, Ca., for
informational technology services and $290,000 to the Mitchell
Group of Woodland Hills, Ca., also for information technology services.
presented to the CIRM governing board at its meeting next week. The
list does not usually trigger any significant discussion.
Source:Stem Cell Therapy
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August 25th, 2013
New Ties to Big Pharma and Venture Capital Proposed at California Stem Cell Agency
By Dr. Matthew Watson
agency wants to recruit major biotech and venture capital firms to
help provide tens of millions of dollars in research awards to
California enterprises.
partnerships in a relatively new, $80 million, business-friendly program that is aimed at pushing therapies into the
marketplace. The recruitment plan will come before the agency's governing board at its meeting next Wednesday in San Diego.
special relationship with the state agency, including early input
into concept funding proposals prior to their being presented to the
agency's governing board. The “industry collaborators” will also
be able to attend agency workshops and meetings involving
hundreds of grant recipients. Presumably other, non-collaborating
firms would be barred.
special event-hosting arrangements aimed at creating more
collaborations and posting of information from the selected
collaborators on the CIRM website.
initiative would be limited to biotech and pharmaceutical firms with
a market capitalization of at least $500 million and “qualified
venture capital firms.” The document did not define what a
“qualified a venture capital firm” is. The document also appeared
to bar participation of privately held firms because of the “market
capitalization” criteria, which typically uses a formula involving
publicly traded shares.
counsel and vice president, business development, said in a statement
provided to the California Stem Cell Report,
“This is aimed at trying to jump
start the creation of the partnerships that are required to satisfy
the commercial validation requirements of the Strategic Partnership
Funding Initiative so that timelines are better synced-up as between
our review and approval cycles for the Strategic Partnership RFAs and
the lengthy time required for investors to conduct due diligence and
negotiate an agreement with prospective applicants to Strategic
Partnership RFAs. CIRM's independent review and approval
remains the same and is wholly independent. While there may be input
given to a particular RFA it only at the high level concept stage and
of course CIRM has no obligation to agree. In the context of the
Strategic Partnership awards, CIRM wants to fund innovative high
quality science that has attracted additional investors.
Investors will help leverage CIRM fund and will be an important
source of future funding to further the project.”
http://feedproxy.google.com/~r/blogspot/uqpFc/~3/ZtmnBmRh5K0/new-ties-to-big-pharma-and-venture.html
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August 25th, 2013
Ghana to tap into genetic engineering – Biochemist – Ghana Business News
By Dr. Matthew Watson
 Ghana Business News | Ghana to tap into genetic engineering – Biochemist Ghana Business News Dr Yaa Difie Osei, a biochemist and molecular biologist, has said the country was positioning itself to tap into the benefits of modern biotechnology and genetic engineering for guaranteed food security. She said structures including institutional and ... |
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August 18th, 2013
Genetic engineering project begins with glow-in-the-dark rabbits, but it could … – MedCity News
By Dr. Matthew Watson
 ABC News | Genetic engineering project begins with glow-in-the-dark rabbits, but it could ... MedCity News The point of the flashy genetic engineering is not to give pet store owners a new product to hawk, but rather to confirm that the techniques researchers use to transfer genes into a genome are working. And in many cases, the greater goal is to develop ... UNIVERSITY OF HAWAII AT MANOAStuff.co.nz A Gene That Was Not Originally in Animals Now ExistsFrench Tribune |
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August 18th, 2013
Unhidden Traits: Genomic Data Privacy Debates Heat Up
By Dr. Matthew Watson
Earlier this year Yaniv Erlich of the Whitehead Institute for Biomedical Research at M.I.T. sent bioethicists into a frenzy when he and his team uncovered the names of people whose anonymous genome...
-- Read more on ScientificAmerican.com
http://rss.sciam.com/~r/sciam/topic/gene-therapy/~3/c3dvzwuFAUI/article.cfm
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August 18th, 2013