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How old are you, really? The answer is written on your face. – National Geographic UK

By daniellenierenberg

How old are you, really? The answer is written on your face.  National Geographic UK

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A Possible Connection between Mild Allergic Airway Responses and Cardiovascular Risk Featured in Toxicological Sciences – Newswise

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A Possible Connection between Mild Allergic Airway Responses and Cardiovascular Risk Featured in Toxicological Sciences  Newswise

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What is an Intrusion Prevention System? Definition … – Fortinet

By daniellenierenberg

While intrusion detection systems (IDS) monitor the network and send alerts to network administrators about potential threats, intrusion prevention systems take more substantial actions to control access to the network, monitor intrusion data, and prevent attacks from developing.

IPS evolved from IDS. IDS technology uses the same concept of identifying traffic and some of the similar techniques with the major difference being that IPS are deployed in-line and IDS are deployed off-line or on tap where they still inspect a copy of the entire traffic or flow but cannot take any preventive action. IDS are deployed to only monitor and provide analytics and visibility into the threats on the network.

Historically, IPS only reacted to cyber breaches, but this reactive stance is no longer satisfactory. IPS is now part of full network security suites, including threat monitoring, firewalls, intrusion detection, anti-virus, anti-malware, ransomware prevention, spam detection, and security analytics.

Recent trends in IPS include using AI to automate the detection process. The future of IPS technology extends network perimeter security with a multi-layered defense. Cloud IPS services perform this security function using extended detection, response, and endpoint protection.

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What is an IPS Monitor? Monitor Panel Types Explained …

By daniellenierenberg

Advantages of IPS display panels:

If youve ever begun searching for a new computer screen, chances are youve probably come across the term IPS. Its at this point that you may be asking yourself,what is an IPS monitor?Andhow do I know if an IPS monitor is right for me?

To answer these questions we must first understand two things:

So, why is this important? A monitors panel technology is important because it affectswhat the monitor can doandfor which uses it is best suited.Each of the monitor panel types listed above offer their own distinctive benefits and drawbacks.

Choosing which type of monitor panel type to buy will depend largely on your intended usage and personal preference.After all, gamers, graphic designers, and office workers all have different requirements. Specific types of displays are best suited for different usage scenarios.

The specific type of LCD panel affects many different aspects of screen performance including:

Different panel technologies offer unique profiles with opinions on thebesttype of LCD being subjective and based on personal preference.

The reason for this is because none of the different monitor panel types as they are today can be classified as outstanding forallof the attributes mentioned above.

Below well take a look at how IPS, TN, and VA monitors affect screen performance and do some handy summaries of strengths, weaknesses, and best-case uses for each type of panel technology.

IPS monitors or In-Plane Switching monitors, leverage liquid crystals aligned in parallel to produce rich colors. IPS panels are defined by the shifting patterns of their liquid crystals. These monitors were designed to overcome the limitations of TN panels. The liquid crystals ability to shift horizontallycreates better viewing angles.

IPS monitors continue to be the display technology of choice for users that wantcolor accuracy and consistency. IPS monitors are really great when it comes tocolor performanceandsuper-wide viewing angles. The expansive viewing angles provided by IPS monitors help to deliver outstanding color when being viewed from different angles. One major differentiator between IPS monitors and TN monitors is that colors on an IPS monitor wont shift when being viewed at an angle as drastically as they do on a TN monitor.

IPS monitor variations include S-IPS, H-IPS, e-IPS and P-IPS, and PLS (Plane-to-Line Switching), the latter being the latest iteration. Since these variations are all quite similar, they are all collectively referred to as IPS-type panels. They all claim to deliver the major benefits associated with IPS monitors great color and ultra-wide viewing angles.

When it comes to color accuracy, IPS monitors surpass the performance of TN and VA monitors with ease. While latest-gen VA technologies offer comparative performance specs, pro users still claim thatIPS monitors reign supremein this regard.

Another important characteristic of IPS monitors is that they are able to support professional color space technologies, such asAdobe RGB. This is due to the fact that IPS monitors are able to offer more displayable colors, which help improve color accuracy.

In the past, response time and contrast were the initial weakness of IPS technology. Nowadays, however, IPS monitor response times have advanced to the point where they are even capable of satisfying gamers, thus resulting in a rising popularity inIPS monitors for gaming.

With regard to gaming, some criticisms IPS monitors include more visible motion blur coming as a result of slower response times, however the impact of motion blur will vary from user to user. In fact, mixed opinions about the drawbacks of IPS monitor for gaming can be found all across the web. Take this excerpt from one gaming technology writer for example: As for pixel response, opinions vary. I personally think IPS panels are quick enough for almost all gaming. If your gaming life is absolutely and exclusively about hair-trigger shooters, OK, youll want the fastest response, lowest latency LCD monitor. And that means TN. For the rest of us, and certainly for those who place even a modicum of importance on the visual spectacle of games, I reckon IPS is clearly the best panel technology. Read the full articlehere.

IPS monitors deliver ultra-wide 178-degree vertical and horizontal viewing angles. Graphic designers, CAD engineers, pro photographers, and video editors will benefit from using an IPS monitor. Many value the color benefits of IPS monitors and tech advances have improved IPS panel speed, contrast, and resolution. IPS monitors are more attractive than ever for general desktop work as well as many types of gaming. Theyre even versatile enough to be used in different monitor styles, so if youve ever compared an ultrawide vs. dual monitorsetup or considered the benefits ofcurved vs. flat monitors, chances are youve already come into contact with an IPS panel.

IPS Monitor Advantages:

IPS Monitor Drawbacks:

IPS Monitor Best Uses:

TN monitors, or Twisted Nematic monitors, are the oldest LCD panel types around. TN panels cost less than their IPS and VA counterparts and are a popular mainstream display technology for desktop and laptop displays.

Displays based on this monitor panel technology are ideal for cost-conscious consumers and entry-level multipurpose use.

Despite their lower perceived value, TN-based displays are the panel typepreferred by competitive gamers. The reason for this is because TN panels can achieve arapid response timeand thefastest refresh rates on the market(like this240Hz eSports monitor). To this effect, TN monitors are able toreduce blurring and screen tearingin fast-paced games when compared to an IPS or VA panel.

On the flip side,however, TN panel technology tends to be ill-suited for applications that benefit from wider viewing angles, higher contrast ratios, and better color accuracy. That being said, LED technology has helped shift the perspective and todays LED-backlit TN models offer higher brightness along with better blacks and higher contrast ratios.

The greatest constraint of TN panel technology, however, is a narrower viewing angle as TN monitors experience more color shifting than other types of panels when being viewed at an angle.

Todays maximum possible viewing angles are 178 degrees both horizontally and vertically (178/178), yet TN panels are limited to viewing angles of approximately 170 degrees horizontal and 160 degrees vertical (170 /160).

In fact, TN monitor can sometimes be easily identified by the color distortion and contrast shifting thats visible at the edges of the screen. As screen sizes increase, this issue becomes even more apparent as reduced color performance can even begin to be seen when viewing the screen from a dead-center position.

For general-purpose use, these shifts in color and contrast are often irrelevant and fade from conscious perception. However, this color variability makes TN monitors a poor choice for color-critical work like graphic design and photo editing. Graphic designers and other color-conscious users should also avoid TN displays due to their more limited range of color display compared to the other technologies.

TN monitors are the least expensive panel technology, making them ideal for cost-conscious businesses and consumers. In addition, TN monitors enjoy unmatched popularity with competitive gamers and other users who seek rapid graphics display.

TN Monitor Advantages:

TN Monitor Drawbacks:

TN Monitor Best Uses:

Vertical alignment (VA) panel technology was developed to improve upon the drawbacks of TN. Current VA-based monitors offer much higher contrast, better color reproduction, and wider viewing angles than TN panels. Variations you may see include P-MVA, S-MVA, and AMVA (Advanced MVA).

These high-end VA-type monitors rival IPS monitors as the best panel technology for professional-level color-critical applications. One of the standout features of VA technology is that it is particularly good at blocking light from the backlight when its not needed. This enables VA panels to display deeper blacks and static contrast ratios of up to several times higher than the other LCD technologies. The benefit of this is that VA monitors with high contrast ratios can deliver intense blacks and richer colors.

Contrast ratio is themeasured difference between the darkest blacks and the brightest whites a monitor can produce. This measurement provides information about the amount of grayscale detail a monitor will deliver. The higher the contrast ratio, the more visible detail.

These monitors also provide more visible details in shadows and highlights, making them ideal for enjoying videos and movies. Theyre also a good fit for games focused on rich imagery (RPG games for example) rather than rapid speed (such as FPS games).

MVA and other recent VA technologies offer the highest static contrast ratios of any panel technology. This allows for an outstanding visual experience for movie enthusiasts and other users seeking depth of detail. Higher-end, feature-rich MVA displays offer the consistent, authentic color representation needed by graphic designers and other pro users.

VA Monitor Advantages:

VA Monitor Drawbacks:

VA Monitor Best uses:

How does OLED compare to LCD?

There is another type of panel technology that differs from the monitor types discussed above and that is OLED or Organic Light Emitting Diode technology. OLEDs differ from LCDs because they use positively/negatively charged ions to light up every pixel individually, while LCDs use a backlight, which can create an unwanted glow. OLEDs avoid screen glow (and create darker blacks) by not using a backlight. One of the drawbacks of OLED technology is that it is usually pricier than any of the other types of technology explained.

Choosing the Right LCD Panel Technology

When it comes to choosing the right LCD panel technology, there is no single right answer. Each of the three primary technologies offers distinct strengths and weaknesses. Looking at different features and specs helps you identify which monitor best fits your needs.

With the lowest cost and fastest response times, TN monitors are great for general use and gaming. VA monitor offers a step up for general use. Maxed-out viewing angles and high contrast ratios make VA monitors great for watching movies and image-intensive gaming.

IPS monitors offer the greatest range of color-related features and remain the gold standard for photo editing and color-critical pro uses. Greater availability and lower prices make IPS monitors a great fit for anyone who values outstanding image quality.

LCD or Liquid Crystal Display is a type of monitor panel that embraces thin layers of liquid crystals sandwiched between two layers of filters and electrodes.

While CRT monitors used to fire electrons against glass surfaces, LCD monitors operate using backlights and liquid crystals. The LCD panel is a flat sheet of material that contains layers of filters, glass, electrodes, liquid crystals, and a backlight. Polarized light (meaning only half of it shines through) is directed towards a rectangular grid of liquid crystals and beamed through.

Liquid Crystals (LCs) are used because of their unique ability to maintain a parallel shape. Acting as both a solid and liquid, LCs are able to react quickly to changes in light patterns. The optical properties of LCs are activated by electric current, which is used to switch liquid crystals between phases. In turn, each pixel generates an RGB (red, green, blue) color based on the phase its in.

Note: When searching for monitors you can be sure to come across the term LED Panel at some point or another. An LED panel is an LCD screen with an LED (Light Emitting Diode) backlight. LEDs provide a brighter light source while using much less energy. They also have the ability to produce white color, in addition to traditional RGB color, and are the panel type used in HDR monitors.

Early LCD panels usedpassive-matrix technologyand were criticized for blurry imagery. The reason for this is because quick image changes require liquid crystals to change phase quickly and passive matrix technology was limited in terms of how quickly liquid crystals could change phase.

As a result,active-matrix technologywas invented andtransistors(TFTs) began being used to help liquid crystals retain their charge and change phase more quickly.

Thanks to active-matrix technology,LCD monitor panels were able to change images very quickly and the technology began being used by newer LCD panels.

Ultimately, budget and feature preferences will determine the best fit for each user. Among the available monitors of each panel type there will also be a range of price points and feature sets. Additionally, overall quality may vary among manufacturers due to factors related to a displays components, manufacturing, and design.

If youre interested in learning more about IPS monitors, you can take a look at some of theseprofessional monitorsto see if they would be the right fit for you.

Alternatively, if youre into gaming and are in the market for TN panel thesegaming monitoroptions may be along the lines of what youre looking for.

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IPS panel – Wikipedia

By daniellenierenberg

IPS (in-plane switching) is a screen technology for liquid-crystal displays (LCDs). In IPS, a layer of liquid crystals is sandwiched between two glass surfaces. The liquid crystal molecules are aligned parallel to those surfaces in predetermined directions (in-plane). The molecules are reoriented by an applied electric field, whilst remaining essentially parallel to the surfaces to produce an image. It was designed to solve the strong viewing angle dependence and low-quality color reproduction of the twisted nematic field effect (TN) matrix LCDs prevalent in the late 1980s.[1]

The TN method was the only viable technology for active matrix TFT LCDs in the late 1980s and early 1990s. Early panels showed grayscale inversion from up to down,[2] and had a high response time (for this kind of transition, 1ms is visually better than 5ms). In the mid-1990s new technologies were developedtypically IPS and Vertical Alignment (VA)that could resolve these weaknesses and were applied to large computer monitor panels.

One approach patented in 1974 was to use inter-digitated electrodes on one glass substrate only to produce an electric field essentially parallel to the glass substrates.[3][4] However, the inventor was not yet able to implement such IPS-LCDs superior to TN displays.

After thorough analysis, details of advantageous molecular arrangements were filed in Germany by Guenter Baur et al. and patented in various countries including the US on 9 January 1990.[5][6] The Fraunhofer Society in Freiburg, where the inventors worked, assigned these patents to Merck KGaA, Darmstadt, Germany.

Shortly thereafter, Hitachi of Japan filed patents to improve this technology. A leader in this field was Katsumi Kondo, who worked at the Hitachi Research Center.[7] In 1992, engineers at Hitachi worked out various practical details of the IPS technology to interconnect the thin-film transistor array as a matrix and to avoid undesirable stray fields in between pixels.[8][9] Hitachi also improved the viewing angle dependence further by optimizing the shape of the electrodes (Super IPS). NEC and Hitachi became early manufacturers of active-matrix addressed LCDs based on the IPS technology. This is a milestone for implementing large-screen LCDs having acceptable visual performance for flat-panel computer monitors and television screens. In 1996, Samsung developed the optical patterning technique that enables multi-domain LCD. Multi-domain and in-plane switching subsequently remain the dominant LCD designs through 2006.[10]

Later, LG Display and other South Korean, Japanese, and Taiwanese LCD manufacturers adapted IPS technology.

IPS technology is widely used in panels for TVs, tablet computers, and smartphones. In particular, most IBM products was marketed as Flexview from 2004 to 2008 has an IPS LCDs with CCFL backlighting, and all Apple Inc. products marketed with the label Retina Display[11][12] feature IPS LCDs with LED backlighting since 2010.

In this case, both linear polarizing filters P and A have their axes of transmission in the same direction. To obtain the 90 degree twisted nematic structure of the LC layer between the two glass plates without an applied electric field (OFF state), the inner surfaces of the glass plates are treated to align the bordering LC molecules at a right angle. This molecular structure is practically the same as in TN LCDs. However, the arrangement of the electrodes e1 and e2 is different. Because they are in the same plane and on a single glass plate, they generate an electric field essentially parallel to this plate. The diagram is not to scale: the LC layer is only a few micrometers thick and so is very small compared with the distance between the electrodes.

The LC molecules have a positive dielectric anisotropy and align themselves with their long axis parallel to an applied electrical field. In the OFF state (shown on the left), entering light L1 becomes linearly polarized by polarizer P. The twisted nematic LC layer rotates the polarization axis of the passing light by 90 degrees, so that ideally no light passes through polarizer A. In the ON state, a sufficient voltage is applied between electrodes and a corresponding electrical field E is generated that realigns the LC molecules as shown on the right of the diagram. Here, light L2 can pass through polarizer A.

In practice, other schemes of implementation exist with a different structure of the LC molecules for example without any twist in the OFF state. As both electrodes are on the same substrate, they take more space than TN matrix electrodes. This also reduces contrast and brightness.[16]

Super-IPS was later introduced with better response times and colour reproduction.[17][unreliable source?]

Toward the end of 2010 Samsung Electronics introduced Super PLS (Plane-to-Line Switching) with the intent of providing an alternative to the popular IPS technology which is primarily manufactured by LG Display. It is an "IPS-type" panel technology, and is very similar in performance features, specs and characteristics to LG Display's offering. Samsung adopted PLS panels instead of AMOLED panels, because in the past AMOLED panels had difficulties in realizing full HD resolution on mobile devices. PLS technology was Samsung's wide-viewing angle LCD technology, similar to LG Display's IPS technology.[24]

Samsung asserted the following benefits of Super PLS (commonly referred to as just "PLS") over IPS:[25]

In 2012 AU Optronics began investment in their own IPS-type technology, dubbed AHVA. This should not be confused with their long standing AMVA technology (which is a VA-type technology). Performance and specs remained very similar to LG Display's IPS and Samsung's PLS offerings. The first 144Hz compatible IPS-type panels were produced in late 2014 (used first in early 2015) by AUO, beating Samsung and LG Display to providing high refresh rate IPS-type panels.[26][27]

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Bone health: Tips to keep your bones healthy – Mayo Clinic

By daniellenierenberg

Bone health: Tips to keep your bones healthy

Protecting your bone health is easier than you think. Understand how diet, physical activity and other lifestyle factors can affect your bone mass.

Bones play many roles in the body providing structure, protecting organs, anchoring muscles and storing calcium. While it's important to build strong and healthy bones during childhood and adolescence, you can take steps during adulthood to protect bone health, too.

Your bones are continuously changing new bone is made and old bone is broken down. When you're young, your body makes new bone faster than it breaks down old bone, and your bone mass increases. Most people reach their peak bone mass around age 30. After that, bone remodeling continues, but you lose slightly more bone mass than you gain.

How likely you are to develop osteoporosis a condition that causes bones to become weak and brittle depends on how much bone mass you attain by the time you reach age 30 and how rapidly you lose it after that. The higher your peak bone mass, the more bone you have "in the bank" and the less likely you are to develop osteoporosis as you age.

A number of factors can affect bone health. For example:

You can take a few simple steps to prevent or slow bone loss. For example:

Include plenty of calcium in your diet. For adults ages 19 to 50 and men ages 51 to 70, the Recommended Dietary Allowance (RDA) is 1,000 milligrams (mg) of calcium a day. The recommendation increases to 1,200 mg a day for women age 51 and older and for men age 71 and older.

Good sources of calcium include dairy products, almonds, broccoli, kale, canned salmon with bones, sardines and soy products, such as tofu. If you find it difficult to get enough calcium from your diet, ask your doctor about supplements.

Pay attention to vitamin D. Your body needs vitamin D to absorb calcium. For adults ages 19 to 70, the RDA of vitamin D is 600 international units (IUs) a day. The recommendation increases to 800 IUs a day for adults age 71 and older.

Good sources of vitamin D include oily fish, such as salmon, trout, whitefish and tuna. Additionally, mushrooms, eggs and fortified foods, such as milk and cereals, are good sources of vitamin D. Sunlight also contributes to the body's production of vitamin D. If you're worried about getting enough vitamin D, ask your doctor about supplements.

If you're concerned about your bone health or your risk factors for osteoporosis, including a recent bone fracture, consult your doctor. He or she might recommend a bone density test. The results will help your doctor gauge your bone density and determine your rate of bone loss. By evaluating this information and your risk factors, your doctor can assess whether you might be a candidate for medication to help slow bone loss.

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Bone marrow drive held for military wife with cancer

By daniellenierenberg

Karina Hernandez, a nurse, mother and wife of a military officer, was diagnosed with cancer.

SAN ANTONIO A bone marrow registry was held Sunday for the wife of an Air Force Major stationed here in San Antonio.

Karina Hernandez, a nurse at BAMC, mother and wife of a military officer, was diagnosed with a rare bone marrow cancer called Myelofibrosis back in 2017 while pregnant.

She had severe pain in her side that wouldn't go away. Testing revealed that not only was she pregnant, she had an enlarged spleen due to Myelofibrosis.

We spoke with her awesome husband, Major Jesse Hernandez on Sunday about the challenges they have faced.

"Her cancer has progressed to the point where she know requires a bone marrow transplant in order to save her life," said Major Hernandez. "So today we're running a bone marrow registry drive with the goal to find a match for my wife and maybe for other patients who are facing the same need."

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There are over 18,000 patients that could benefit from healthy bone marrow and it could save their life.

"Karina continues to work at BAMC caring for other people, all while battling cancer," said Major Hernandez. "She has been on chemo medications the whole time and this is my opportunity to try and help her and hopefully find someone who is a match to help her."

Her friends and family all say Karina cares more about getting people to sign up for the registry to help others.

She is concerned that - It's not just for herself, it's for how many other people can be helped by this, said Dora Lopez, one of the drives organizers.

Unfortunately, Hispanics do not commonly sign themselves up as donors, said her family. So it has been difficult to try and find a match for her.

"The chances of a Caucasian patient finding a matches is 79% Hispanics is a 48% chance and African Americans is only a 29% chance," said Be The Match Recruitment Coordinator Melinda Dixon.

A bone marrow registry in her honor was held Sunday at St. Anthony Mary Claret Catholic Church located at 6150 Roft Road from 7 a.m. to 7 p.m.

If you missed the drive, you can still sign up for the registry by following this link or by texting Cure4Karina to 61474.

You must be at least 18 years old to register. You will not be asked to donate right away, only to swab the inside of your cheeks to send in so your DNA can be added to the national registry. if it is a match for a patient, a donation could save a life.

Since going on the air in 1950, KENS 5has strived to be the best, most trusted news and entertainment source for generations of San Antonians.

KENS 5 has brought numerous firsts to South Texas television, including being the first local station with a helicopter, the first with its own Doppler radar and the first to air a local morning news program.

Over the years, KENS 5 has worked to transform local news. Our cameras have been the lens bringing history into local viewers' homes. We're proud of our legacy as we serve San Antonians today.

Today, KENS 5 continues to set the standard in local broadcasting and is recognized by its peers for excellence and innovation. The KENS 5 News team focuses on stories that really matter to our community.

You can find KENS 5 in more places than ever before, including KENS5.com, the KENS 5 app, the KENS 5 YouTube channel, KENS 5's Roku and Fire TV apps, and across social media on Facebook, Twitter, Instagram and more!

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Bone cancer – Symptoms and causes – Mayo Clinic

By daniellenierenberg

Overview

Bone cancer can begin in any bone in the body, but it most commonly affects the pelvis or the long bones in the arms and legs. Bone cancer is rare, making up less than 1 percent of all cancers. In fact, noncancerous bone tumors are much more common than cancerous ones.

The term "bone cancer" doesn't include cancers that begin elsewhere in the body and spread (metastasize) to the bone. Instead, those cancers are named for where they began, such as breast cancer that has metastasized to the bone.

Some types of bone cancer occur primarily in children, while others affect mostly adults. Surgical removal is the most common treatment, but chemotherapy and radiation therapy also may be utilized. The decision to use surgery, chemotherapy or radiation therapy is based on the type of bone cancer being treated.

Signs and symptoms of bone cancer include:

Make an appointment with your doctor if you or your child develops bone pain that:

Subscribe for free and receive an in-depth guide to coping with cancer, plus helpful information on how to get a second opinion. You can unsubscribe at any time.

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The cause of most bone cancers is unknown. A small number of bone cancers have been linked to hereditary factors, while others are related to previous radiation exposure.

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Osteosarcoma, the most common type of bone cancer, often starts in the long bones the legs or the arms but it can occur in any bone.

Bone cancers are broken down into separate types based on the type of cell where the cancer began. The most common types of bone cancer include:

It's not clear what causes bone cancer, but doctors have found certain factors are associated with an increased risk, including:

Bone cancer care at Mayo Clinic

March 22, 2022

Connect with others like you for support and answers to your questions in the Cancer support group on Mayo Clinic Connect, a patient community.

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Skin: Layers, Structure and Function – Cleveland Clinic

By daniellenierenberg

Overview The three layers of skin on top of muscle tissue.What is the skin?

The skin is the bodys largest organ, made of water, protein, fats and minerals. Your skin protects your body from germs and regulates body temperature. Nerves in the skin help you feel sensations like hot and cold.

Your skin, along with your hair, nails, oil glands and sweat glands, is part of the integumentary (in-TEG-you-MEINT-a-ree) system. Integumentary means a bodys outer covering.

Three layers of tissue make up the skin:

Your epidermis is the top layer of the skin that you can see and touch. Keratin, a protein inside skin cells, makes up the skin cells and, along with other proteins, sticks together to form this layer. The epidermis:

The dermis makes up 90% of skins thickness. This middle layer of skin:

The bottom layer of skin, or hypodermis, is the fatty layer. The hypodermis:

One inch of your skin has approximately 19 million skin cells and 60,000 melanocytes (cells that make melanin or skin pigment). It also contains 1,000 nerve endings and 20 blood vessels.

As the bodys external protection system, your skin is at risk for various problems. These include:

You lose collagen and elastin as you age. This causes the skins middle layer (dermis) to get thinner. As a result, the skin may sag and develop wrinkles.

While you cant stop the aging process, these actions can help maintain healthier skin:

You should call your healthcare provider if you experience:

A note from Cleveland Clinic

As the bodys largest organ, your skin plays a vital role in protecting your body from germs and the elements. It keeps your body at a comfortable temperature, and nerves beneath the skin provide the sense of touch. This external body covering can have serious problems like skin cancer, as well as more common issues like acne and skin rashes. Your healthcare provider can offer tips to help keep skin healthy.

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Human skin | Definition, Layers, Types, & Facts | Britannica

By daniellenierenberg

Summary

human skin, in human anatomy, the covering, or integument, of the bodys surface that both provides protection and receives sensory stimuli from the external environment. The skin consists of three layers of tissue: the epidermis, an outermost layer that contains the primary protective structure, the stratum corneum; the dermis, a fibrous layer that supports and strengthens the epidermis; and the subcutis, a subcutaneous layer of fat beneath the dermis that supplies nutrients to the other two layers and that cushions and insulates the body.

The apparent lack of body hair immediately distinguishes human beings from all other large land mammals. Regardless of individual or racial differences, the human body seems to be more or less hairless, in the sense that the hair is so vestigial as to seem absent; yet in certain areas hair grows profusely. These relatively hairy places may be referred to as epigamic areas, and they are concerned with social and sexual communication, either visually or by scent from glands associated with the hair follicles.

The characteristic features of skin change from the time of birth to old age. In infants and children it is velvety, dry, soft, and largely free of wrinkles and blemishes. Children younger than two years sweat poorly and irregularly; their sebaceous glands function minimally. At adolescence hair becomes longer, thicker, and more pigmented, particularly in the scalp, axillae, pubic eminence, and the male face. General skin pigmentation increases, localized pigmented foci appear mysteriously, and acne lesions often develop. Hair growth, sweating, and sebaceous secretion begin to blossom. As a person ages, anatomical and physiological alterations, as well as exposure to sunlight and wind, leave skin, particularly that not protected by clothing, dry, wrinkled, and flaccid.

Human skin, more than that of any other mammal, exhibits striking topographic differences. An example is the dissimilarity between the palms and the backs of the hands and fingers. The skin of the eyebrows is thick, coarse, and hairy; that on the eyelids is thin, smooth, and covered with almost invisible hairs. The face is seldom visibly haired on the forehead and cheekbones. It is completely hairless in the vermilion border of the lips, yet coarsely hairy over the chin and jaws of males. The surfaces of the forehead, cheeks, and nose are normally oily, in contrast with the relatively greaseless lower surface of the chin and jaws. The skin of the chest, pubic region, scalp, axillae, abdomen, soles of the feet, and ends of the fingers varies as much structurally and functionally as it would if the skin in these different areas belonged to different animals.

The skin achieves strength and pliability by being composed of numbers of layers oriented so that each complements the others structurally and functionally. To allow communication with the environment, countless nervessome modified as specialized receptor end organs and others more or less structurelesscome as close as possible to the surface layer, and nearly every skin organ is enwrapped by skeins of fine sensory nerves.

The dermis makes up the bulk of the skin and provides physical protection. It is composed of an association of fibres, mainly collagen, with materials known as glycosaminoglycans, which are capable of holding a large amount of water, thus maintaining the turgidity of the skin. A network of extendable elastic fibres keeps the skin taut and restores it after it has been stretched.

The hair follicles and skin glands are derived from the epidermis but are deeply embedded in the dermis. The dermis is richly supplied with blood vessels, although none penetrates the living epidermis. The epidermis receives materials only by diffusion from below. The dermis also contains nerves and sense organs at various levels.

Human skin is enormously well supplied with blood vessels; it is pervaded with a tangled, though apparently orderly, mass of arteries, veins, and capillaries. Such a supply of blood, far in excess of the maximum biologic needs of the skin itself, is evidence that the skin is at the service of the blood vascular system, functioning as a cooling device. To aid in this function, sweat glands pour water upon its surface, the evaporation of which absorbs heat from the skin. If the environment is cold and body heat must be conserved, cutaneous blood vessels contract in quick, successive rhythms, allowing only a small amount of blood to flow through them. When the environment is warm, they contract at long intervals, providing a free flow of blood. During muscular exertion, when great quantities of generated heat must be dissipated, blood flow through the skin is maximal.

In addition to its control of body temperature, skin also plays a role in the regulation of blood pressure. Much of the flow of blood can be controlled by the opening and closing of certain sphincterlike vessels in the skin. These vessels allow the blood to circulate through the peripheral capillary beds or to bypass them by being shunted directly from small arteries to veins.

Human skin is permeated with an intricate mesh of lymph vessels. In the more superficial parts of the dermis, minute lymph vessels that appear to terminate in blind sacs function as affluents of a superficial lymphatic net that in turn opens into vessels that become progressively larger in the deeper portions of the dermis. The deeper, larger vessels are embedded in the loose connective tissue that surrounds the veins. The walls of lymph vessels are so flabby and collapsed that they often escape notice in specimens prepared for microscopic studies. Their abundance, however, has been demonstrated by injecting vital dyes inside the dermis and observing the clearance of the dye.

Because lymph vessels have minimal or no musculature in their walls, the circulation of lymph is sluggish and largely controlled by such extrinsic forces as pressure, skeletal muscle action, massaging, and heat. Any external pressure exerted, even from a fixed dressing, for example, interferes with its flow. Since skin plays a major role in immunologic responses of the body, its lymphatic drainage is as significant as its blood vascular system.

The intact surface of the skin is pitted by the orifices of sweat glands and hair folliclesthe so-called poresand is furrowed by intersecting lines that delineate characteristic patterns. All individuals have roughly similar markings on any one part of the body, but the details are unique. The lines are oriented in the general direction of elastic tension. Countless numbers of them, deep and shallow, together with the pores, give every region of the body a characteristic topography. Like the deeper furrows and ridges on the palms and soles, the skin lines are mostly established before birth. The fine details of each area of body surface are peculiar to each individual. Fingerprints are used as a means of personal identification because they have a high relief, more evident patternings, and can be easily obtained.

Some of the lines on the surface of the skin are acquired after birth as a result of use or damage. For example, furrows on the forehead are an accentuation of preexisting congenital lines that become strongly emphasized in old age. As the skin becomes less firm with aging, it also forms wrinkles. Certain occupations leave skin marks that, depending upon duration and severity, may be transient or permanent.

The palms of the hands and the soles of the feet are etched by distinct alternating ridges and grooves that together constitute dermatoglyphics. The ridges follow variable courses, but their arrangement in specific areas has a consistent structural plan. Though apparently continuous, the ridges have many interruptions and irregularities, branching and varying in length. Every small area of surface has ridge details not matched anywhere in the same individual or in any other individual, even in an identical twin. This infallible signature makes dermatoglyphics the best-known physical characteristic for personal identification.

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Skin Disorders: Pictures, Causes, Symptoms, and Treatment – Healthline

By daniellenierenberg

Skin disorders vary greatly in symptoms and severity. They can be temporary or permanent and may be painless or painful. Some skin conditions are minor, and others can be life threatening.

Some skin disorders have situational causes, while others may be genetic. While most skin disorders are minor, others can indicate a more serious issue.

Contact a doctor if you believe you may have one of these common skin problems.

There are many different types of skin disorders. Here are pictures of 25 different conditions, followed by a list of details for each.

Learn more about acne.

Learn more about cold sores and cold sores on dark skin.

Learn more about blisters.

Learn more about hives.

Learn more about actinic keratosis.

Learn more about rosacea.

Learn more about carbuncles.

This condition is considered a medical emergency. Urgent care may be required. Contact 911 or local emergency services.

Learn more about latex allergies.

Learn more about eczema.

Learn more about psoriasis.

Cellulitis is a medical emergency. A person should contact 911 or local emergency services if they have any symptoms of cellulitis.

Learn more about cellulitis.

Learn more about measles.

Learn more about basal cell carcinoma.

Learn more about squamous cell carcinoma.

Learn more about melanoma.

Learn more about lupus.

Learn more about contact dermatitis.

Learn more about vitiligo.

Learn more about warts.

Learn more about chickenpox.

Learn more about seborrheic eczema.

Learn more about keratosis pilaris.

Learn more about ringworm.

Learn more about melasma.

Learn more about impetigo.

Contact dermatitis is one of the most common occupational illnesses, often resulting from contact with chemicals or other irritating materials.

These substances can trigger a reaction that causes the skin to become itchy and inflamed. Affected areas might also appear red, purple, gray, or dark brown. Most cases of contact dermatitis arent severe, but they can be rather itchy.

Topical creams and avoiding the irritant are typical treatments.

Keratosis pilaris is a minor condition that causes small, rough bumps on the skin. These bumps usually form on the upper arms, thighs, or cheeks. Theyre typically red or white and dont hurt or itch.

Treatment isnt necessary, but medicated creams can improve skin appearance.

Some chronic skin conditions present from birth, while others appear suddenly later.

The cause of these disorders isnt always known. Many permanent skin disorders have effective treatments that enable extended periods of remission. However, theyre incurable, and symptoms can reappear at any time.

Examples of chronic skin conditions include:

Skin disorders are common in children. Children can experience many of the same skin conditions as adults. Infants and toddlers are also at risk of diaper-related skin problems.

Since children have more frequent exposure to other children and germs, they may also develop skin disorders that rarely occur in adults.

Many childhood skin problems disappear with age, but children can also inherit permanent skin disorders. In most cases, doctors can treat childhood skin disorders with topical creams, medicated lotions, or condition-specific drugs.

Common childhood skin disorders include:

Skin conditions have a wide range of symptoms. Symptoms on your skin that appear due to common problems arent always the result of a skin disorder. Such symptoms can include blisters from new shoes or chafing from tight pants.

However, skin problems with no obvious cause may indicate the presence of a skin disorder that requires treatment.

Skin irregularities that are typically symptoms of a skin disorder include:

Common known causes of skin disorders include:

Numerous health conditions and lifestyle factors can also lead to the development of certain skin disorders. Some skin conditions have no known cause.

Inflammatory bowel disease is a term for a group of intestinal disorders that cause prolonged inflammation of the digestive tract. These bowel-related disorders often cause skin problems.

The drugs used to treat these diseases can cause certain skin conditions, such as:

Many people with diabetes experience a skin problem due to their condition at some point.

Some of these skin disorders only affect people with diabetes. Others occur more frequently in people with diabetes because the disease increases the risk of infection and blood circulation problems.

Diabetes-related skin conditions include:

Lupus is a chronic inflammatory disease that can damage the skin, joints, or organs inside the body. Common skin problems that occur from lupus include:

Pregnancy causes significant changes in hormone levels that may lead to skin problems. Preexisting skin problems may change or get worse during pregnancy. Most skin conditions that arise during pregnancy go away after the baby is born. Others require medical attention during pregnancy.

Common skin conditions caused by pregnancy include:

Stress can cause hormonal imbalances, which may trigger or aggravate skin disorders. Stress-related skin problems include:

The sun can cause many different skin disorders. Some are common and harmless, while others are rare or life threatening. Knowing if the sun causes or worsens your skin disorder is important for treating it properly.

Sunlight exposure may cause or aggravate the following conditions:

Many skin disorders are treatable. Common treatment methods for skin conditions include:

Not all skin disorders respond to treatment, and some conditions go away without treatment.

People with permanent skin conditions often go through periods of severe symptoms. Sometimes people are able to force incurable conditions into remission. However, most skin conditions reappear due to certain triggers, such as stress or illness.

You can often treat skin disorders that are temporary and cosmetic with:

Certain skin disorders arent preventable, including genetic conditions and some skin problems due to other illnesses. However, its possible to prevent some skin disorders.

Follow these tips to prevent infectious skin disorders:

Noninfectious skin disorders, such as acne and atopic dermatitis, are sometimes preventable. Prevention techniques vary depending on the condition. Here are some tips for preventing some noninfectious skin disorders:

Learning about proper skin care and treatment for skin disorders can be very important for skin health. Some conditions require a doctors attention, while you can address others safely at home.

You should learn about your symptoms or condition and talk with a doctor to determine the best treatment methods.

According to the American Academy of Dermatology Association, acne is the most common skin condition in the United States. Other common skin disorders include atopic dermatitis, hair loss, and rosacea.

There are several serious skin conditions. In particular, melanoma is a type of skin cancer that can be especially dangerous, as it could spread to other parts of the body if not caught early. Cellulitis and latex allergy can also be very serious if left untreated.

A few examples of chronic skin conditions include rosacea, psoriasis, and vitiligo. While these conditions cant be cured, some may have treatments available to help manage symptoms.

Different types of conditions affect the skin. Some are chronic, while others are temporary. Some conditions may be painful or uncomfortable, but theyre not dangerous. Other conditions, such as skin cancer, can be life threatening.

The treatment for each depends on the specific cause. If you experience any new or unusual skin symptoms, its a good idea to have them evaluated by a doctor.

Read this article in Spanish.

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Skin Care and Aging | National Institute on Aging

By daniellenierenberg

Cynthias story

Cynthia had always been proud of her skin, especially her summer tan. But, as years went by, she saw her skin getting more fine lines and wrinkles. Cynthia began to worry about what other skin problems she might have. What were those brown spots on her hands and arms?

Your skin changes with age. It becomes thinner, loses fat, and no longer looks as plump and smooth as it once did. Your veins and bones can be seen more easily. Scratches, cuts, or bumps can take longer to heal. Years of suntanning or being out in the sunlight for a long time may lead to wrinkles, dryness, age spots, and even cancer. But there are things you can do to protect your skin and to make it feel and look better.

Many older people suffer from dry spots on their skin, often on their lower legs, elbows, and lower arms. Dry skin patches feel rough and scaly. There are many possible reasons for dry skin, such as:

Dry skin also can be caused by health problems, such as diabetes or kidney disease. Using too much soap, antiperspirant, or perfume and taking hot baths can make dry skin worse.

Some medicines can make skin itchy. Because older people have thinner skin, scratching can cause bleeding that may lead to infection. Talk to your doctor if your skin is very dry and itchy.

Here are some ways to help dry, itchy skin:

Older people may bruise more easily than younger people. It can take longer for these bruises to heal. Some medicines or illnesses may also cause bruising. Talk to your doctor if you see bruises and dont know how you got them, especially on parts of your body usually covered by clothing.

Over time, skin begins to wrinkle. Things in the environment, like ultraviolet (UV) light from the sun, can make the skin less elastic. Gravity can cause skin to sag and wrinkle. Certain habits, like smoking, also can wrinkle the skin.

A lot of claims are made about ways to make wrinkles go away. Most of them dont work. Some methods can be painful or even dangerous, and many must be done by a doctor. Talk with a doctor specially trained in skin problems, called a dermatologist, or your regular doctor if you are worried about wrinkles.

Age spots, once called liver spots, are flat, brown spots often caused by years in the sun. They are bigger than freckles and commonly show up on areas like the face, hands, arms, back, and feet. Using a broad-spectrum sunscreen that helps protect against two types of the suns rays (UVA and UVB) may prevent more age spots.

Skin tags are small, usually flesh-colored growths of skin that have a raised surface. They become common as people age, especially for women. They are most often found on the eyelids, neck, and body folds such as the armpit, chest, and groin.

Age spots and skin tags are harmless, although sometimes skin tags can become irritated. If your age spots or skin tags bother you, talk to your doctor about having them removed.

Skin cancer is a very common type of cancer in the United States. The main cause of skin cancer is the sun. Sunlamps and tanning booths can also cause skin cancer. Anyone, of any skin color, can get skin cancer. People with fair skin that freckles easily are at greatest risk. Skin cancer may be cured if it is found before it spreads to other parts of the body.

There are three types of skin cancers. Two types, basal cell carcinoma and squamous cell carcinoma, grow slowly and rarely spread to other parts of the body. These types of cancer are usually found on parts of the skin most often exposed to the sun, like the head, face, neck, hands, and arms. But they can happen anywhere on your body. The third and most dangerous type of skin cancer is melanoma. It is rarer than the other types, but it can spread to other organs and be deadly.

Check your skin once a month for things that may be signs of cancer. Skin cancer is rarely painful. Look for changes such as a new growth, a sore that doesnt heal, or a bleeding mole.

A = Asymmetry (one half of the growth looks different from the other half)

B = Borders that are irregular

C = Color changes or more than one color

D = Diameter greater than the size of a pencil eraser

E = Evolving; meaning the growth changes in size, shape, symptoms (itching, tenderness), surface (especially bleeding), or shades of color

See your doctor right away if you have any of these signs to make sure it is not skin cancer.

Some sun can be good for you, but to keep your skin healthy, be careful:

Your skin may change with age. But remember, there are things you can do to help. Check your skin often. If you find any changes that worry you, see your doctor.

Read about this topic in Spanish. Lea sobre este tema en espaol.

This content is provided by the NIH National Institute on Aging (NIA). NIA scientists and other experts review this content to ensure it is accurate and up to date.

Content reviewed: October 01, 2017

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Skin care: 5 tips for healthy skin – Mayo Clinic

By daniellenierenberg

Skin care: 5 tips for healthy skin

Good skin care including sun protection and gentle cleansing can keep your skin healthy and glowing.

Don't have time for intensive skin care? You can still pamper yourself by acing the basics. Good skin care and healthy lifestyle choices can help delay natural aging and prevent various skin problems. Get started with these five no-nonsense tips.

One of the most important ways to take care of your skin is to protect it from the sun. A lifetime of sun exposure can cause wrinkles, age spots and other skin problems as well as increase the risk of skin cancer.

For the most complete sun protection:

Smoking makes your skin look older and contributes to wrinkles. Smoking narrows the tiny blood vessels in the outermost layers of skin, which decreases blood flow and makes skin paler. This also depletes the skin of oxygen and nutrients that are important to skin health.

Smoking also damages collagen and elastin the fibers that give your skin strength and elasticity. In addition, the repetitive facial expressions you make when smoking such as pursing your lips when inhaling and squinting your eyes to keep out smoke can contribute to wrinkles.

In addition, smoking increases your risk of squamous cell skin cancer. If you smoke, the best way to protect your skin is to quit. Ask your doctor for tips or treatments to help you stop smoking.

Daily cleansing and shaving can take a toll on your skin. To keep it gentle:

A healthy diet can help you look and feel your best. Eat plenty of fruits, vegetables, whole grains and lean proteins. The association between diet and acne isn't clear but some research suggests that a diet rich in fish oil or fish oil supplements and low in unhealthy fats and processed or refined carbohydrates might promote younger looking skin. Drinking plenty of water helps keep your skin hydrated.

Uncontrolled stress can make your skin more sensitive and trigger acne breakouts and other skin problems. To encourage healthy skin and a healthy state of mind take steps to manage your stress. Get enough sleep, set reasonable limits, scale back your to-do list and make time to do the things you enjoy. The results might be more dramatic than you expect.

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Wrinkles – Symptoms and causes – Mayo Clinic

By daniellenierenberg

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Wrinkles, especially around the eyes, mouth and neck, are common with aging as the skin in these areas gets thinner, drier and less elastic.

Wrinkles, a natural part of aging, are most prominent on sun-exposed skin, such as the face, neck, hands and forearms.

Although genetics mainly determine skin structure and texture, sun exposure is a major cause of wrinkles, especially for people with light skin. Pollutants and smoking also contribute to wrinkling.

If your wrinkles bother you, you have more options than ever to help smooth them or make them less visible. Medications, skin-resurfacing techniques, fillers and surgery top the list of effective wrinkle treatments.

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With repeated sun exposure, wrinkles can become very pronounced and deep, especially on the back of the neck.

Wrinkles are the lines and creases that form in your skin. Some wrinkles can become deep crevices or furrows and may be especially noticeable around your eyes, mouth and neck.

If you're concerned about the appearance of your skin, see a dermatologist. He or she can assess your skin and help you create a personalized skin care plan. A dermatologist can also recommend medical wrinkle treatments.

Wrinkles are caused by a combination of factors some you can control, others you can't:

Age. As you get older, your skin naturally becomes less elastic and more fragile. Decreased production of natural oils dries your skin and makes it appear more wrinkled.

Fat in the deeper layers of your skin diminishes. This causes loose, saggy skin and more-pronounced lines and crevices.

Exposure to ultraviolet (UV) light. Ultraviolet radiation, which speeds the natural aging process, is the primary cause of early wrinkling. Exposure to UV light breaks down your skin's connective tissue collagen and elastin fibers, which lie in the deeper layer of skin (dermis).

Without the supportive connective tissue, your skin loses strength and flexibility. Skin then begins to sag and wrinkle prematurely.

Here are some tips for protecting your skin and minimizing the appearance of wrinkles:

Protect your skin from the sun. Limit the time you spend in the sun, especially midday, and always wear protective clothing, such as wide-brimmed hats, long-sleeved shirts and sunglasses. Also, use sunscreen year-round when outdoors.

Choose a skin-care product with a built-in sun protection factor (SPF) of at least 15. The American Academy of Dermatology recommends using a broad-spectrum sunscreen with an SPF of 30 or more. Apply sunscreen generously, and reapply every two hours or more often if you're swimming or perspiring.

Wrinkles care at Mayo Clinic

Jan. 21, 2023

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Dry skin – Symptoms and causes – Mayo Clinic

By daniellenierenberg

Vivien Williams: Drink plenty of water. Don't smoke and wash your face and body each day with a gentle hypoallergenic soap for healthy-looking skin says Mayo Clinic dermatologist, Dr. Dawn Davis. And, after bathing,

Dawn Davis, M.D., Dermatology, Mayo Clinic: Moisturize with a hypoallergenic, fragrance-free moisturizer when you're done to help the skin hydrate.

Vivien Williams: With so many products from which to choose, how do you pick the right moisturizer? Dr. Davis says hypoallergenic is the key.

Dr. Davis: So you want it to be fragrance-free. Unscented doesn't necessarily mean that it doesn't have fragrance. Oftentimes unscented just means more chemicals.

Vivien Williams: What ingredient should you look for?

Dr. Davis: The most inert natural hypoallergenic product that you can find in a moisturizer is petrolatum.

Vivien Williams: As in petroleum jelly. Dr. Davis has another important tip for healthy skin care that could potentially save your life.

Dr. Davis: Please remember to wear your sunscreen.

Vivien Williams: For the Mayo Clinic News Network, I'm Vivien Williams.

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Bone | Definition, Anatomy, & Composition | Britannica

By daniellenierenberg

Top Questions

What is bone made of?

The two principal components of bone are collagen and calcium phosphate, which distinguish it from other hard tissues such as chitin, enamel, and shell.

What are the major functions of bone tissue?

Bone tissue makes up the individual bones of the skeletons of vertebrates. The other roles of bone include structural support for the mechanical action of soft tissues, protection of soft organs and tissues, provision of a protective site for specialized tissues such as the blood-forming system (bone marrow), and a mineral reservoir.

Do bones contain calcium?

Bone contains 99 percent of the calcium in the body and can behave as an adequate buffer for maintaining a constant level of freely moving calcium in soft tissues, extracellular fluid, and blood.

Why is calcium important for bone health?

The mechanical strength of bone is proportional to its mineral content. The Food and Nutrition Board of the U.S. National Academy of Sciences has recommended 1,0001,300 mg of calcium daily for adults and 7001,300 mg for children.

How does vitamin D deficiency affect bones in humans?

A deficiency in vitamin D results in poor mineralization of the bones of the skeleton, causing rickets in children and osteomalacia in adults.

Summary

bone, rigid body tissue consisting of cells embedded in an abundant hard intercellular material. The two principal components of this material, collagen and calcium phosphate, distinguish bone from such other hard tissues as chitin, enamel, and shell. Bone tissue makes up the individual bones of the human skeletal system and the skeletons of other vertebrates.

The functions of bone include (1) structural support for the mechanical action of soft tissues, such as the contraction of muscles and the expansion of lungs, (2) protection of soft organs and tissues, as by the skull, (3) provision of a protective site for specialized tissues such as the blood-forming system (bone marrow), and (4) a mineral reservoir, whereby the endocrine system regulates the level of calcium and phosphate in the circulating body fluids.

Bone is found only in vertebrates, and, among modern vertebrates, it is found only in bony fish and higher classes. Although ancestors of the cyclostomes and elasmobranchs had armoured headcases, which served largely a protective function and appear to have been true bone, modern cyclostomes have only an endoskeleton, or inner skeleton, of noncalcified cartilage and elasmobranchs a skeleton of calcified cartilage. Although a rigid endoskeleton performs obvious body supportive functions for land-living vertebrates, it is doubtful that bone offered any such mechanical advantage to the teleost (bony fish) in which it first appeared, for in a supporting aquatic environment great structural rigidity is not essential for maintaining body configuration. The sharks and rays are superb examples of mechanical engineering efficiency, and their perseverance from the Devonian Period attests to the suitability of their nonbony endoskeleton.

In modern vertebrates, true bone is found only in animals capable of controlling the osmotic and ionic composition of their internal fluid environment. Marine invertebrates exhibit interstitial fluid compositions essentially the same as that of the surrounding seawater. Early signs of regulability are seen in cyclostomes and elasmobranchs, but only at or above the level of true bone fishes does the composition of the internal body fluids become constant. The mechanisms involved in this regulation are numerous and complex and include both the kidney and the gills. Fresh and marine waters provide abundant calcium but only traces of phosphate; because relatively high levels of phosphate are characteristic of the body fluids of higher vertebrates, it seems likely that a large, readily available internal phosphate reservoir would confer significant independence of external environment on bony vertebrates. With the emergence of terrestrial forms, the availability of calcium regulation became equally significant. Along with the kidney and the various component glands of the endocrine system, bone has contributed to development of internal fluid homeostasisthe maintenance of a constant chemical composition. This was a necessary step for the emergence of terrestrial vertebrates. Furthermore, out of the buoyancy of water, structural rigidity of bone afforded mechanical advantages that are the most obvious features of the modern vertebrate skeleton.

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What Is Bone? | NIH Osteoporosis and Related Bone Diseases National …

By daniellenierenberg

To understand osteoporosis, it is important to learn about bone. Made mostly of collagen, bone is living, growing tissue. Collagen is a protein that provides a soft framework, and calcium phosphate is a mineral that adds strength and hardens the framework. This combination of collagen and calcium makes bone strong and flexible enough to withstand stress. More than 99 percent of the body's calcium is contained in the bones and teeth. The remaining 1 percent is found in the blood.

Two types of bone are found in the bodycortical and trabecular. Cortical bone is dense and compact. It forms the outer layer of the bone. Trabecular bone makes up the inner layer of the bone and has a spongy, honeycomb-like structure.

Think of bone as a bank account where you deposit and withdraw bone tissue. During childhood and the teenage years, new bone is added to the skeleton faster than old bone is removed. As a result, bones become larger, heavier, and denser. For most people, bone formation continues at a faster pace than removal until bone mass peaks during the third decade of life.

After age 20, bone withdrawals can begin to exceed deposits. For many people, this bone loss can be prevented by continuing to get calcium, vitamin D, and exercise and by avoiding tobacco and excessive alcohol use. Osteoporosis develops when bone removal occurs too quickly, replacement occurs too slowly, or both. You are more likely to develop osteoporosis if you did not reach your maximum peak bone mass during your bone-building years.

Women are more likely than men to develop osteoporosis. This is because women generally have smaller, thinner bones than men have and because women can lose bone tissue rapidly in the first 4 to 8 years after menopause because of the sharp decline in production of the hormone estrogen. Produced by the ovaries, estrogen has been shown to have a protective effect on bone. Women usually go through menopause between age 45 and 55. After menopause, bone loss in women greatly exceeds that in men. However, by age 65, women and men tend to lose bone tissue at the same rate. Although men do not undergo the equivalent of menopause, production of the male hormone testosterone may decrease, and this can lead to increased bone loss and a greater risk of developing osteoporosis.

Osteoporosis is preventable for many people. Prevention is important because although there are treatments for osteoporosis, a cure has not yet been found. A comprehensive program that can help prevent osteoporosis includes:

The National Institutes of Health Osteoporosis and Related Bone Diseases ~National Resource Center acknowledges the assistance of theNational Osteoporosis Foundation in the preparation of this publication.

For updates and for any questions about any medications you are taking, please contact

U.S. Food and Drug AdministrationToll Free: 888-INFO-FDA (888-463-6332)Website: https://www.fda.gov

For additional information on specific medications, visit Drugs@FDA at https://www.accessdata.fda.gov/scripts/cder/daf. Drugs@FDA is a searchable catalog of FDA-approved drug products.

NIH Pub. No. 18-7876

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Bone Definition & Meaning – Merriam-Webster

By daniellenierenberg

often attributive

1

: one of the hard parts of the skeleton of a vertebrate

: any of various hard animal substances or structures (such as baleen or ivory) akin to or resembling bone

: the hard largely calcareous connective tissue of which the adult skeleton of most vertebrates is chiefly composed

2

3

bones plural

: the basic design or framework (as of a play or novel)

5

bones plural : thin bars of bone, ivory, or wood held in pairs between the fingers and used to produce musical rhythms

: a strip of material (such as whalebone or steel) used to stiffen a garment (such as a corset)

6

transitive verb

1

2

: to provide (a garment) with stays

3

: to rub (something, such as a boot or a baseball bat) with something hard (such as a piece of bone) in order to smooth the surface

4

US, vulgar slang : to have sexual intercourse with (someone)

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Anatomy of the Bone | Johns Hopkins Medicine

By daniellenierenberg

What is bone?

Bone is living tissue that makes up the body's skeleton. There are 3 types of bone tissue, including the following:

Compact tissue. The harder, outer tissue of bones.

Cancellous tissue. The sponge-like tissue inside bones.

Subchondral tissue. The smooth tissue at the ends of bones, which is covered with another type of tissue called cartilage. Cartilage is the specialized, gristly connective tissue that is present in adults. It is also the tissue from which most bones develop in children.

The tough, thin outer membrane covering the bones iscalled theperiosteum. Beneath the hard outer shell of the periosteum are tunnels and canals through which blood and lymphatic vessels run to carry nourishment for the bone. Muscles, ligaments, and tendons may attach to the periosteum.

Bones are classified by their shapeas long, short, flat, and irregular. Primarily, they are referred to as long or short.

There are 206 bones in the human skeleton, not including teeth and sesamoid bones (small bones found within cartilage):

80 axial bones. This includes the head, facial, hyoid, auditory, trunk, ribs, and sternum.

126 appendicular bones. This includes arms, shoulders, wrists, hands, legs, hips, ankles, and feet.

Bone provides shape and support for the body, as well as protection for some organs. Bone also serves as a storage site for minerals and provides the mediummarrowfor the development and storage of blood cells.

The different types of bone cells include the following:

Osteoblast. Found within the bone, its function is to form new bone tissue.

Osteoclast. A very large cell formed in bone marrow, its function is to absorb and remove unwanted tissue.

Osteocyte. Found within the bone, its function is to help maintain bone as living tissue.

Hematopoietic. Found in bone marrow, its function is to produce red blood cells,white blood cells, and platelets.

Fat cells are also found within the bone marrow.

Because of the complexities of a bone's function, from providing strength and support for the body, to serving as a site for development and storage of blood cells, there are many disorders and diseases that can affect bone.

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Bone Health: Is Eating Meat Healthy For Your Bones?

By daniellenierenberg

High protein intake from meat can lead to calcium loss and harm bone health

As to how consuming animal or plant protein impacts bone composition, many studies have been published. Numerous studies have shown that compared to plant-based protein, animal-based protein weakens bones. According to several research, persons who consume a lot of meat are more likely to develop osteoporosis (thin bone tissue) and fractures.

Resorption and formation of new bone are constantly balanced in healthy bones. Resorption is the breakdown of old bone to be reabsorbed (modeling). Most individuals are aware of the significance of calcium and vitamin D in the development and maintenance of strong bones. However, a theory that protein altered the body's natural chemistry in such a way that too much calcium was being excreted in urine emerged based on past research.

In one of her recent Instagram posts, nutritionist Anjali Mukerjee shares how meat protein can impact bone health. She writes, A high protein diet, especially from animal sources, can lead to calcium loss and harm bone health.

Meat has a high phosphorous-to-calcium ratio which increases calcium excretion and can cause bone demineralization.

Consuming animal protein, especially red meat, can make the blood acidic and lead to calcium being removed from bones.

She further writes, Protein is important for bone health, but too much animal protein, especially red meat, can actually harm your bones. So we need to make sure to include dairy, fish, chicken, and plant-based sources of protein in your diet, and don't forget to balance it with plenty of fruits, vegetables, and whole grains.

Look at her post:

Disclaimer: This content including advice provides generic information only. It is in no way a substitute for a qualified medical opinion. Always consult a specialist or your own doctor for more information. NDTV does not claim responsibility for this information.

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