By Reuters By Reuters July 8 at 8:47 AM

Stem cell tourism in which patients travel to developing countries for unproven and potentially risky therapies should be more tightly regulated, according to a group of international health experts.

With hundreds of medical centers around the world claiming to be able to repair tissue damaged by conditions such as multiple sclerosis and Parkinsons disease, tackling unscrupulous advertising of such procedures is crucial.

These therapies are advertised directly to patients with the promise of a cure, but there is often little or no evidence to show they will help or that they will not cause harm, the 15 experts wrote in the journal Science Translational Medicine.

Some types of stem cell transplant mainly using blood and skin stem cells have been approved by regulators after full clinical trials found they could treat certain types of cancer and grow skin grafts for burn patients.

But many other potential therapies are only in the earliest stages of development and have not been approved by regulators.

Stem cell therapies hold a lot of promise, but we need rigorous clinical trials and regulatory processes to determine whether a proposed treatment is safe, effective and better than existing treatments, said one of the 15, Sarah Chan of Britains University of Edinburgh.

The experts called for global action, led by the World Health Organization, to introduce controls on advertising and to agree on international standards for the manufacture and testing of cell- and tissue-based therapies.

The globalization of health markets and the specific tensions surrounding stem cell research and its applications have made this a difficult challenge, they wrote. However, the stakes are too high not to take a united stance.

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LIMA Employers in the greater West Central Ohio region will collect $33 million in rebates from the Ohio Bureau of Workers Compensation in checks that will be mailed beginning next week.

BWC Administrator/CEO Sarah Morrison, in Lima to present a ceremonial check to local business leaders, said employers are free to spend their rebates as they wish, but she hopes they will consider investing in workplace safety.

We work with employers all over Ohio to prevent injuries and illness in the workplace, and they will tell you that investing in safety is a wise business decision, said Morrison, speaking at a press conference at the Lima/Allen County Chamber of Commerce. Safe workplaces mean fewer injuries, fewer medical claims and a stable workforce, all of which leads to a healthy bottom line for a business.

Morrison was joined by chamber President/CEO Jed Metzger and Tony Daley of Limas Spallinger Millwright Services Inc. Metzger and Daley accepted the check on behalf of employers in the entire region, which includes Allen, Auglaize, Shelby, Hancock, Putnam, and Van Wert counties.

Ohio Gov. John Kasich proposed the rebate in March. Its the third such rebate in the last four years, made possible by an improving safety climate, prudent fiscal management and strong investment returns. The plan to distribute rebates to more than 200,000 Ohio employers during the month of July was approved by BWCs Board of Directors in April. Visitbwc.ohio.govfor more details and eligibility requirements.

The plan also includes a $44 million investment innew health and safety initiativesto promote a healthy workforce and a culture of safety in every Ohio workplace. This includes a new wellness program for small employers, funding for programs to help firefighters and those who work with children and adults with disabilities, and an education campaign to address common injuries at work and in the home.

A healthy economy depends on a strong and healthy workforce, Morrison continued. And when the economy is healthy, we all benefit.

Rebate checks will be mailed in phases starting July 10.

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Antabuse doctors - Antabuse interactions with perfume - Van Wert independent

Derek Richardson

July 3rd, 2017

The CRS-11 Dragon capsule re-enters Earths atmosphere. Photo Credit: Jack Fischer / NASA

SpaceXs CRS-11 Dragon capsule splashed down at 8:12 a.m. EDT (12:12 GMT) on July 3, 2017, in the Pacific Ocean just off the coast of Baja California after some 28 days attached to the International Space Station.

After being unberthed using the robotic Canadarm2, the craft was moved to a location some 33 feet (10 meters) below the Destiny laboratory module. It was officially released at 2:41 a.m. EDT (6:41 GMT) on July 3 by Expedition 52 astronauts Jack Fischer and Peggy Whitson of NASA.

The CRS-11 Dragon capsule is positioned for release beneath the ISS. Photo Credit: Jack Fischer / NASA

Dragons been an incredible spacecraft, Fischer said after release. I could even say it was slathered in awesome sauce. This baby has had almost no problems, which is an incredible feat considering its the first reuse of a Dragon vehicle.

The CRS-11 Dragon capsule pressure vessel was the same one used during the CRS-4 mission in 2014.

And the science weve done oh my, the science, Fischer said. Most of the 6,000 pounds [2,700 kilograms] of cargo carried was science, and almost all of the return cargo are precious samples for discoveries we cant wait to see.

Fischer explained that Dragon also brought up various external experiments too, including an external platform for science, a neutron star analyzer and an experimental solar array that was rolled out like a party horn on New Years Eve.

The science on this mission has been non-stop, and we think the scientists will be extremely happy with the volumes of data we gathered for them up here in space in our floating world-class laboratory we call home, Fischer said. For the whole SpaceX team, thank you for building such a great vehicle and for finding us some good weather today to allow us to bring home the science on time. Godspeed and fair winds, Dragon-11.

The spacecraft had originally been planned to splash down on July 2, but due to a forecast of unacceptable sea conditions at the recovery zone, mission managers decided on June 30 to postpone the capsules departure from the station.

Three separate departure burns were performed by the Dragon capsule once the robotic arm released the spacecraft. This gradually pushed the vehicle away from the outpost and outside the 656-foot (200-meter) Keep-Out Sphere (KOS).

Some five hours later, Dragon, using its Draco thrusters, performed a 10-minute de-orbit burn. Minutes after that, its trunk, which is not recoverable, was jettisoned.

Moments after being released by the ISS crew, the CRS-11 Dragon capsule begins its journey back to Earth. Photo Credit: Jack Fischer / NASA

A few minutes before splashing down, the capsule released drogue chutes to slow the capsule a bit and to keep a specific attitude for the three main parachutes to bedeployed. Once that occurred, along with a successful splashdown, it ensured a successful mission for the first re-flight of a commercial spacecraft to and from the ISS.

Now that Dragon is back on Earth and on a recovery ship, it will now be transported to the port of Los Angeles to offload time-sensitive cargo. The most notable include the Fruit Fly Lab-02 experiment, the Systemic Therapy of NELL-1 for osteoporosis study, and the Cardiac Stem Cells experiment.

The Fruit Fly Lab-02 experiment aims to understand the effects of prolonged microgravity exposure on the heart. According to NASA, because flies are small, have a well-known genetic makeup, and age rapidly, thatmakes them good models for heart function studies.

For the Systemic Therapy of NELL-1 for osteoporosis study, a group of rodents were used as models to test a drug that can rebuild bone and block additional bone density loss. It is hoped that this can help reduce bone density loss for astronauts on extended stays in space. Additionally, it can potentially help people with osteoporosis.

According to NASA, in-flight countermeasures, like exercise, can prevent bone density loss from getting worse, but nothing on Earth or in space can restore bone density.

Finally, the Cardiac Stem Cells experiment aims to analyze how microgravity affects stem cells and factors that govern stem cell activity. NASA says the study focuses on cardiac stem cell functions and has numerous biomedical and commercial applications.

The CRS-11 Dragon was launched June 3 from Kennedy Space Centers Launch Complex 39A in Florida. After a two-day rendezvous profile, the capsule was berthed to the Earth-facing port of the Harmony module on June 5.

The next Dragon mission will be CRS-12 on Aug. 10, 2017. It is unclear if this capsule will also be a pre-flown vessel.

Video courtesy of NASA

Tagged: CRS-11 Dragon Expedition 52 International Space Station Lead Stories NASA SpaceX

Derek Richardson has a degree in mass media, with an emphasis in contemporary journalism, from Washburn University in Topeka, Kansas. While at Washburn, he was the managing editor of the student run newspaper, the Washburn Review. He also has a blog about the International Space Station, called Orbital Velocity. He met with members of the SpaceFlight Insider team during the flight of a United Launch Alliance Atlas V 551 rocket with the MUOS-4 satellite. Richardson joined our team shortly thereafter. His passion for space ignited when he watched Space Shuttle Discovery launch into space Oct. 29, 1998. Today, this fervor has accelerated toward orbit and shows no signs of slowing down. After dabbling in math and engineering courses in college, he soon realized his true calling was communicating to others about space. Since joining SpaceFlight Insider in 2015, Richardson has worked to increase the quality of our content, eventually becoming our managing editor.

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Dragon splashes down in Pacific with time-critical experiments - SpaceFlight Insider

Jul 7, 2017 - (Newswire)

Remember the story of the golden apples that could grant immortality to the person who ate them? It seemed too good to be true; plants couldn't make you live forever. However, it seems that they can make youage less quickly, and Adore Cosmetics has discovered how to harness their power for more youthful skin.

Plant stem cells are becoming increasingly popular in cosmetic and skin care brands for their apparent anti-aging properties. But what is the hype really about? Are all of the companies claiming this new technology will benefit a persons skin or is this an elaborate scam? Spoiler alert: its not a scam!

Plant stem cell culture technology is a very complicated process that ensures the growth of plant cells in sterile environments. The lab-cultivated culture allows for substances present in plants to be grown where it would otherwise be very difficult to obtain naturally. It results in ingredients that are free from environmental pollutants, available all the time, and with an identical amount of nutrients in every batch.

To test the viability of plant stem cells as an anti-aging product, a Swiss Company called Mibelle Chemistry tested the anti-aging capabilities of a variety of Swiss Apples. The study took place over a 4-week period and measured the depth of crow's feet periodically (every 2 weeks). The moisturizing cream -- which contained the plant stem cells -- was applied twice daily. The results of the study saw a 15% total decrease in depth of the wrinkles after 4 weeks.

Adore Cosmetics, one of the leaders in regards to skincare technologies, is a brand whose entire line of products is formulated with plant stem cells from rare organic Swiss Apples to encourage the renewal of your skins own stem cells.

Adore Cosmeticsproducts protect the skins current stem cells, prevents damage than can occur due to UV stress and environmental factors, and promotes the vitality of skin stem cells. As a result, the skin of people who use Adore Cosmetics isrestored, renewed, and replenished as our organic ingredients encourage it to slow down -- and, according to this study, potentially reverse -- the aging process!

To try out our products, find discounts at http://adorecosmeticsoffers.com/

And to read our beauty blog, Adore Cosmetics Insights, head to https://adorecosmeticsinsights.com/

Follow Adore Cosmetics on Instagram | Twitter | Pinterest

About Adore Cosmetics:Adore Cosmeticsoffers innovations in organic skin care productspowered by plant stem cellsand other beauty-boosting ingredients. Adoreskincareproducts are designed to promote beauty, help reverse the signs of aging, and restore a youthful glow to the skinnaturallyby harnessing the power of nature.

Contact: ArielleFried Adore Cosmetics 305-627-9370 Arielle@AdoreCosmetics.com

Original Source: https://www.newswire.com/news/adore-cosmetics-is-using-apples-to-take-us-one-step-closer-to-19638166

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Adore Cosmetics is Using Apples to Take Us One Step Closer to Agelessness - WireUpdate

A U.S. biomedical researcher believes most babies will be made in the lab instead of the bedroom within the next two to three decades -- a bold prediction that could halt genetic predisposition to certain diseases and introduce a new plane of biological inequality.

Hank Greely, the director of Stanford Law Schools Center for Law and the Biosciences, told attendees at the Aspen Ideas Festival earlier this week that replacing sex as the primary means of baby-making will save women from undergoing fertility treatments, reduce health care costs, and give non-traditional families more avenues to have children.

Greely predicts most prospective parents will soon opt to choose from a range of embryos created by taking female skin samples and using stem cells to create eggs, which are then fertilized with sperm.

The range of embryos would be audited for genetically transmitted diseases such as Huntingtons, and perhaps even DNA indicators for breast cancer and Alzheimers. The process could also allow for the selection of cosmetic features, like hair and eye colour, and even complex traits such as intelligence.

Some of this can already take place through costly pre-implantation genetic diagnostics and in vitro fertilization. But Greely imagines, in the future, such selection will become commonplace as the technology becomes cheaper and perhaps even subsidized due to the offset in other medical costs.

University of Toronto bioethicist Kerry Bowman warns that widespread adoption of multiple embryo selection would be quite a deviation from the status-quo, and would mark a shift that makes longstanding fears about genetic predetermination a reality.

It could lead to inequality. Who could afford such a technique? he asked CTV News Channel on Thursday. When we have some people that are selected to the point of almost being enhanced, weve got more inequality added on top of that.

Beyond the issue of cost and the ethical taboo of so-called designer babies, Bowman points to the moral implications of creating additional embryos with the knowledge that some will be discarded.

What are you going to do with them? He (Greely) seems to be talking about a very large amount of embryos. That is one concern, Bowman said.

With that in mind, however, he expects many people will embrace the rise of scientific intervention in human reproduction for the mere possibility of diminishing the risk of disease.

If you could prevent a child being born into a life of suffering, most people would be very supportive of that, Bowman said. Historically, weve thrown the dice.

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Sex for procreation will be obsolete in 30 years, researcher says - CTV News

TheHorse.com

Take-Homes From the 2017 Equine Ophthalmology Symposium TheHorse.com In her second presentation Schnabel described current progress on ophthalmologic applications of stem cell therapy in horses. She shared recent results of in-vitro (in the lab) studies on bone marrow mesenchymal stem cells (BM-MSC), including their use ...

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Take-Homes From the 2017 Equine Ophthalmology Symposium - TheHorse.com

Asbarez The Armenian Bone Marrow Donor Registry (ABMDR) announced that it has facilitated its 30th bone marrow stem cell transplant, thanks to stem cells harvested from a young ABMDR matched donor. The stem cells of the donor, Sergey, who is a 23 year-old army officer serving on the frontline in Artsakh, were utilized to save the life of a cancer patient in Iran.

On July 3, 2017, Sergey became the 30th ABMDR donor to experience the joy of saving the life of someone he had never met, said ABMDR President Dr. Frieda Jordan.

In 2012, Sergey had joined the ranks of ABMDRs donor registry during a recruitment drive at the Vazken Sagsyan Military Institute, in Yerevan. Five years later, he was found to be a perfect match for a patient in Iran who was suffering from leukemia and whose only hope for survival was to receive a bone marrow stem cell transplant from a compatible donor. Sergey turned out to be a perfect match for the patient. He was given a day off to leave the frontline to come to ABMDRs Stem Cell Harvesting Center in Yerevan to donate his stem cells and save a patients life.

Accompanied by his young wife and six-month old son, Sergey was greeted by ABMDR staff at the Stem Cell Harvesting Center. The painless, non-invasive harvesting procedure, performed by Dr. Andranik Mshetsyan, lasted approximately four hours. Also present at the procedure were ABMDR Executive Director Dr. Sevak Avagyan and Medical Director Dr. Mihran Nazaretyan.

At the conclusion of the harvesting, as staff members performed quality-control analyses of the harvested cells and packed them for the special courier who was waiting to transport the precious gift of life to the patient in Iran, Sergey, a hero in the eyes of all, on the frontlines as well as far away from them, joined his young family while someone in Iran was about to get a second chance at life.

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Artsakh soldier saves life of cancer patient in Iran - Public Radio of Armenia

SpaceX's Dragon cargo craft splashed down in the Pacific Ocean at 8:12 a.m. EDT, west of Baja California and the recovery process is underway, marking the end of the company's eleventh contracted cargo resupply mission to the International Space Station for NASA.

Expedition 52 astronauts Jack Fischer and Peggy Whitson of NASA released the SpaceX Dragon cargo spacecraft from the International Space Station's robotic arm right on schedule, at 2:41 a.m.

A variety of technological and biological studies are returning in Dragon. The Fruit Fly Lab-02 experiment seeks to better understand the effects of prolonged exposure to microgravity on the heart.

Flies are small, with a well-known genetic make-up, and age rapidly, making them good models for heart function studies. This experiment could significantly advance understanding of how spaceflight affects the cardiovascular system and could help develop countermeasures to help astronauts.

Samples from the Systemic Therapy of NELL-1 for osteoporosis will return as part of an investigation using rodents as models to test a new drug that can both rebuild bone and block further bone loss, improving crew health.

When people and animals spend extended periods of time in space, they experience bone density loss, or osteoporosis. In-flight countermeasures, such as exercise, prevent it from getting worse, but there isn't a therapy on Earth or in space that can restore bone density.

The results from this ISS National Laboratory-sponsored investigation is built on previous research also supported by the National Institutes for Health and could lead to new drugs for treating bone density loss in millions of people on Earth.

The Cardiac Stem Cells experiment investigated how microgravity affects stem cells and the factors that govern stem cell activity. The study focuses on understanding cardiac stem cell function, which has numerous biomedical and commercial applications. Scientists will also look to apply new knowledge to the design of new stem cell therapies to treat heart disease on Earth.

The Dragon spacecraft launched June 3 on a SpaceX Falcon 9 rocket from historic Launch Complex 39A at NASA's Kennedy Space Center in Florida, and arrived at the station June 5.

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Dragon Splashes Down to Complete Resupply Mission - Space Daily

Heres an interesting project: somebody has been growing a human hand in a lab and displaying it for the world to see.

We live in a time where the meaning of impossible needs to be updated.

As we make new discoveries, new possibilities open up to us. And if you want a good example of that, just look at how advanced prosthetics have become in the last decade. Soon, you might be able to grow a humanhand like a Chia pet.

Or take a look at Dr. Sergio Canavero, who plans to perform a full-on head transplant later this year.

But that example may be a little extreme.

See, theres something miraculous about giving something vital like a limb or an organ to someone to needs it. In the past, it couldnt be done, but with the future in sight, were slowly changing our minds on that.

So, the future can be full of hope. And when one of us loses a hand, possibly due to someone we have only just learned is our father, we wont have to worry too hard.

Ok, heres a better example of the kind of future Im talking about.

Artist Amy Karle has an interesting new project that combines 3D printing with stem cell research. The idea is to grow a functional human hand, and if it works she wants to make the design free and open source.

And trust me, that will be one weird-yet-cool day for the people who frequent Instructables.com.

Karle may be an artist, but shes no amateur. She works with nonprofit groups that design 3D printed prosthetic arms, and she has help from a team of scientists.

The project is called Regenerative Reliquary, and it is being displayed in San Franciscos Pier 9 space while it grows. Or, to be more accurate, while part of it grows.

Karle has designed a 3D printed trellis in CAD which was printed using a cellular growth medium called pegda. Over several weeks, the pegda trellis was grown in a bioreactor on display. The next step will be to grow a cell line on the trellis, something Karle is culturing stem cells for now.

The team is using stem cells extracted from bone marrow, and with any luck, the idea will bear fruit and be released to the public.

I like the sound of an open source prosthetic design, especially considering how much more of an option 3D printing is these days. Lose a limb, and you may one day be able to make a replacement within the comfort of your own garage.

For now, though, were still waiting to see if Karles project will work. According to the artist, Well see if the cells have a mind of their own. I like to step back and let the artwork take over.

Now you know how Karle plans to grow a human hand. Lets rewind a bit, back to where I mentioned Dr. Canavero and his upcoming head transplant.

As crazy as it sounds, if Canaveros plan works science will have taken a big step toward manipulating the central nervous system. And thats really, really important. If scientists can connect a head to a spine, and they can grow a limb in a tank, it follows that they may one day be able to attach that limb as a replacement.

And that doesnt just apply to limbs, either. Scientists have been looking into growing replacement organs for years, just look at this article from way back in 2014.

We may be on the verge of the ability to reproduce and replace parts of the human body. And at this rate, who knows what kind of effect this can have on the survivability rate of human beings in the future.

Im sure well never resurrect the dead or anything, but I think the fictional Dr. Frankenstein would be proud.

Creating replacement body parts is something that has been a mainstay of science fiction, and it isnt crazy any longer to think that it may become a reality. So, like I said earlier, we may need to push the goal posts back on the word impossible.

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How to Grow a Human Hand - Edgy Labs (blog)

Photo of Patrick Soon-Shiong courtesy NHS Confederation

Billionaire physician Patrick Soon-Shiong's company NantWorks has acquired a majority stake in Integrity Healthcare, the company that manages nonprofit Verity Health System. Terms of the deal were disclosed, but the transaction puts Soon-Shiong's company in place as the new operator of Verity's six California hospitals.

Verity Health employs more than 6,000 staff statewide. Their hospitals include 1,650 inpatient beds, six active emergency rooms, a trauma center and medical specialties including tertiary and quaternary care.

The system's Southern California hospitals include St. Francis Medical Center in Lynwood and St. Vincent Medical Center in Los Angeles. Their Northern California facilities are O'Connor Hospital in San Jose, St. Louise Regional Hospital in Gilroy, Seton Medical Center in Daly City and Seton Coastside in Moss Beach, Verity said in a statement.

New York hedge fund BlueMountain Capital Management formed Integrity Healthcare and is their former majority owner. They, along with NantWorks have committed to continue investing in Verity's revitalization efforts. BlueMountain is making additional funds available for that effort, and will maintain a minority interest in Integrity, Verity said.

Soon-Shiong will join Verity's Board of Investors.

The collaboration between Integrity and NantWorks is expected to yield will include major technological improvements for the hospitals such as diagnostic and imaging services and next generation stem cell therapy. Expanded oncology, cardiac, orthopedic, neurology, urology, transplant and pediatric services are also forecasted, Verity said.

However, the billionaire doctor's activities, including his philanthropic efforts, have been under a cloud of suspicion.

Soon-Shiong and two other pharma executives are being sued by attorneys Boyden Gray and Adam Waldman of Washington, D.C., for allegedly attempting to acquire Altor Bioscience through a sweetheart deal. Altor is a 15-year-old immunotherapy company, with 12 ongoing human clinical trials.

The lawsuit, filed June 21, asserts the deal in place benefits Soon-Shiong, Hing C. Wong and Fred Middleton all board members of Altor Bioscience. The deal comes at the expense of the minority shareholders, which breaches their fiduciary duty.

The connections between his philanthropic efforts and his for-profit businesses have also been under scrutiny after STAT News and Politico investigations.

Both news outlets pointed to possible improprieties stemming from a $12 million dollar donation to the University of Utah made by Soon-Shiong's research foundation, the Chan Soon-Shiong NantHealth Foundation.

Politico's investigation foundthat the foundation contributed $3 million out of the $12 million donated by Soon-Shiong-controlled businesses to a university program to that sought to map the genomes of 1,000 state residents.

"University officials say they let Soon-Shiong's entities write the grant specifications. The specifications gave a major advantage to his for-profit firms, which got the $10 million gene-mapping contract," Politico said.

The investigation also showed that a large portion of the Foundation's expenditures from 2010 to 2015 went to Soon-Shiong-affiliated nonprofits and for-profits, as well as companies that do business with his for-profit entities.

Also, the investigation said six employees of Soon-Shiong's for-profit businesses were paid with Foundation money, which raises questions about the flow of money between the entities.

Soon-Shiong denied any wrongdoing to Politico and STAT.

U.S. House Speaker Paul Ryan appointed the biotech mogul to the Health IT Advisory Committee. The 25-member committee, established through the 21st Century Cures Act, will advise the president and his administration on health IT policy.

Bill Siwicki contributed to this report.

Twitter: @BethJSanborn

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NantWorks acquires majority stake in Integrity Healthcare, will take over 6 Los Angeles hospitals - Healthcare Finance News

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12:55 am | There have been 46 commission races for seats in the five town districts since 2000. Of those, 72 percent, or 33 of them, having only a single...

12:51 am | Town Manager Dave Bullock found the next Public Works Director for Longboat Key close to home....

12:02 am | Rotary Club honors those who protect and serve our island as residents and families show support....

11:51 pm | More stringent ordinance enacted due to LBK having highest number of disorientations in area....

11:48 pm | The Unstoppable Wasp is about females in science working together for a common cause....

11:31 pm | There is no better place Ive run across where residents are as smart, rationally informed and care so much about where they live....

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11:25 pm | Mote Marine Laboratory documented the first three local sea turtle nests of 2017 two on Sunday, April 30, and one on Monday, May 1 in Venice,...

01:58 pm | The stakes could not be higher. The future look of the island, the evolution of property values and the protection of development rights all intersect. ...

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Proventil hfa ventolin hfa - Proventil inhaler dosage for adults - Longboat Key News

LONDON Stem-cell tourism involving patients who travel to developing countries for treatment with unproven and potentially risky therapies should be more tightly regulated, international health experts said on Wednesday.

With hundreds of medical centers around the world claiming to be able to repair damaged tissue in conditions such as multiple sclerosis and Parkinson's disease, tackling unscrupulous advertising of such procedures is crucial.

These therapies are advertised directly to patients with the promise of a cure, but there is often little or no evidence to show they will help, or that they will not cause harm, the 15 experts wrote in the journal Science Translational Medicine.

Some types of stem cell transplant mainly using blood and skin stem cells have been approved by regulators after full clinical trials found they could treat certain types of cancer and grow skin grafts for burns patients.

But many other potential therapies are only in the earliest stages of development and have not been approved by international regulators.

"Stem cell therapies hold a lot of promise, but we need rigorous clinical trials and regulatory processes to determine whether a proposed treatment is safe, effective and better than existing treatments," said one of the 15, Sarah Chan of Britain's University of Edinburgh.

The experts called for global action, led by the World Health Organization, to introduce controls on advertising and agree international standards for the manufacture and testing of cell and tissue-based therapies.

"The globalization of health markets and the specific tensions surrounding stem cell research and its applications

have made this a difficult challenge," they wrote. "However, the stakes are too high not to take a united stance."

(Reporting by Kate Kelland, editing by John Stonestreet)

ZURICH Novartis said that the Committee for Medicinal Products for Human Use (CHMP) has approved a label update for Cosentyx (secukinumab), the first interleukin-17A (IL-17A) approved to treat psoriasis.

(Reuters Health) - After weight-loss surgery, people who get cosmetic procedures to remove excess tissue may have a better quality of life than those who don't get this additional work done, a recent study suggests.

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'Stem-cell tourism' needs tighter controls, say medical experts ... - Reuters

Sure, the main purpose of sex isprocreation, but according to one researcher, in as little as 30 years, we may have more efficient and cheaper ways of making babiesthangood ole fashioned intercourse. According to Hank Greely, the director of StanfordLaw Schools Center for Law and Biosciences, human reproductionmay become automated faster than you realize.

Greely believes that within three decades, people will no longer have sex as a way to reproduce, and instead relyongenetically edited embryos grown from skin-derived stem cells, not the combination of an egg or sperm, The Independent reported. According to Greely, this processensures that the embryo is free from any devastating genetic diseases, and wouldalso be cheaper in the long run because of the money it would save in healthcare over the years. Whats more, Greely predicts that couples would be able to choose other genetic traits in their children, such as physical features and intelligence.

Read: What Is A Three Parent IVF Technique? Worlds First Baby Born Using DNA From Three Parents, But How?

I dont think were going to be able to say this embryo will get a 1550 on its two-part SAT, Greely said this week at Aspen Ideas Festival, Quartz reported, But, this embryo has a 60% chance of being in the top half, this embryo has a 13% chance of being in the top 10%I think thats really possible.

The idea may soundfar-out, but according to Quartz, it already happens on a much smaller and limited scale as a way to prevent certain diseases. Although extremely expensive at the moment, advances in stem cell technology willhelp to drive down the cost. In addition, the amount that the government would save on not having to take care of sick babies would also make this more cost-efficient.

Making babies from skin cellsrather than a traditional egg fertilized with spermmaysound like its straight out of Hollywood, butthetechnology is quickly advancing. The skin cells, one from the mother and the other from the father, are coaxed into becoming an egg or sperm cell, The New York Times reported. This also means that one day same-sex couples may be able to have biologically related children. So far, vitro gametogenesis (IVG), or making sex cells from stem cells, has only worked on mice.

Theres also the worry that being able to genetically manipulate your offspring may lead to a eugenicssituation where less favorable traits get written out of the human genome forever. However, Greely also believes this is not the case.

This is not designer babies or super babies, said Greely, Quartz reported. This is selecting embryos. You take two people, all you can get out of a baby is what those two people have.

Just because well no longer need sex for procreation doesnt mean the activity is going out of fashion anytime soon. It's agreat way to createfuture generations, and sexis also good for your physical and mental health, as well as keeping couples together.

See Also:

Designer Babies: The Truth Behind Preimplantation Genetic Diagnosis

Scientists Edit Human Embryo Genes For First Time Ever: A Step Toward Disease-Free Future?

Link:
Sex For Reproduction May Be Obsolete Within 30 Years Thanks To New Technology, Professor Predicts - Medical Daily

Stem cells have long been used to treat blood cancers and some immune diseases. But some doctors are offering stem cell treatments for diseases still under clinical trial. Photograph: Mauricio Lima/AFP/Getty Images

Medical and legal experts from around the world have united to call for more stringent regulation of stem cell therapies to prevent people pursuing unproven and potentially deadly treatments overseas.

In a perspective piece for the US journal Science Translational Medicine, 15 experts from countries including the UK, the US, Canada, Belgium, Italy and Japan wrote that national efforts alone would not be enough to counter an industry offering unproven treatments to vulnerable patients.

Stem cell-based interventions are classified under diverse and potentially incompatible national regulatory frameworks, the authors wrote.

Approaches for international regulation not only need to develop consistent rules over the commercialisation of medical practices and products but also need to give them teeth by developing cross-border partnerships for compliance.

Stem cells found in bone marrow and umbilical cord blood have long been used to successfully treat blood cancers including leukaemia and some immune diseases. But those are among the few proven treatments. Legitimate and ethics-approved clinical trials by academic centres are also occurring, exploring the potential of stem cells to treat a wider range of diseases.

But some doctors are directly offering to the general public stem cell treatments for diseases still under clinical trial or for which no evidence exists and for which the safety and efficacy is as yet unproven.

Deaths as a result of stem cell treatments have already occurred. In 2013 Sheila Drysdale died in a New South Wales nursing home after undergoing an unproven liposuction stem-cell therapy at a western Sydney clinic. Following Drysldales death, her doctor, Ralph Bright, gave a statement to police in which he claimed that stem-cell treatment could improve comorbidities and that stem cells could move from joints to other parts of the body to improve disease in distant sites including lungs and brain, vision, mentation and pain.

In his report into Drysdales death, the coroner Hugh Dillon wrote that he could not say what motivated Dr Bright to perform this unproven, dubious procedure on Sheila Drysdale.

But regardless of his motivation, Dr Brights performance as a medical practitioner was, for the reasons outlined above, poor and resulted in Sheila Drysdales death.

The Medical Council of NSW investigated Bright and placed a number of restrictions on his right to practice. Bright is still authorised to practise stem cell therapy for patients with osteoarthritis or who are taking part in research studies approved by an ethics committee. He is also still allowed to treat patients returning for remaining injections of stored cells.

In 2013 a Queensland woman, Kellie van Meurs, died when she travelled to Russia to undergo stem-cell treatment for a rare neurological disorder. She died of a heart attack as a result.

Australias drug regulator, the Therapeutic Goods Administration, last year sought feedback on the regulation of autologous stem-cell therapies but is yet to publish those submissions. The TGA now considers autologous treatments, which involve treating someone with their own tissue or cells, to be a therapeutic good and, therefore, does not regulate them. Stem cells used for medical practice and therapeutic purposes are covered by different regulatory frameworks.

Associate Professor Megan Munsie, a University of Melbourne stem cell scientist and a co-author of the paper, said: The idea that stem cells are magical holds court in the community, along with this idea the advances in treatment are being held up by red tape.

Unethical health practitioners exploited this, she said, along with the vulnerability of patients with difficult-to-treat or incurable conditions.

There is a precedent for international regulation of this industry because regulations already exist around drugs the way they are manufactured, she said.

This could be extended to the regulation to the stem cell and tissue-based therapies. This international stance would then force or encourage stronger local regulations.

There have been successful efforts by scientists to push back against unscrupulous doctors. In Italy scientists and regulators highlighted the unproven yet government-subsidised treatments being offered by the entrepreneur Davide Vannoni and fought to stop him. He was convicted of criminal charges but the sentence was later suspended.

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Stem cell therapies: medical experts call for strict international rules - The Guardian

Sergey with his wife and son

ABMDR salutes young officer and celebrates its 30th life saved through a transplant

LOS ANGELESThe Armenian Bone Marrow Donor Registry (ABMDR) announced that it has facilitated its 30th bone marrow stem cell transplant, thanks to stem cells harvested from a young ABMDR matched donor. The stem cells of the donor, Sergey, who is a 23 year-old army officer serving on the frontline in Artsakh, were utilized to save the life of a cancer patient in Iran.

On July 3, 2017, Sergey became the 30th ABMDR donor to experience the joy of saving the life of someone he had never met, said ABMDR President Dr. Frieda Jordan.

Dr. Sevak Avagyan, Sergey, Dr. Andranik Mshetsyan

In 2012, Sergey had joined the ranks of ABMDRs donor registry during a recruitment drive at the Vazken Sagsyan Military Institute, in Yerevan. Five years later, he was found to be a perfect match for a patient in Iran who was suffering from leukemia and whose only hope for survival was to receive a bone marrow stem cell transplant from a compatible donor. Sergey turned out to be a perfect match for the patient. He was given a day off to leave the frontline to come to ABMDRs Stem Cell Harvesting Center in Yerevan to donate his stem cells and save a patients life.

Accompanied by his young wife and six-month old son, Sergey was greeted by ABMDR staff at the Stem Cell Harvesting Center. The painless, non-invasive harvesting procedure, performed by Dr. Andranik Mshetsyan, lasted approximately four hours. Also present at the procedure were ABMDR Executive Director Dr. Sevak Avagyan and Medical Director Dr. Mihran Nazaretyan.

Sergey, Dr. Mihran Nazaretyan, and Lab Staff Member

At the conclusion of the harvesting, as staff members performed quality-control analyses of the harvested cells and packed them for the special courier who was waiting to transport the precious gift of life to the patient in Iran, Sergey, a hero in the eyes of all, on the frontlines as well as far away from them, joined his young family while someone in Iran was about to get a second chance at life.

Established in 1999, ABMDR, a nonprofit organization, helps Armenians and non-Armenians worldwide survive life-threatening blood-related illnesses by recruiting and matching donors to those requiring bone marrow stem cell transplants. To date, the registry has recruited over 29,000 donors in 42 countries across four continents, identified over 4,190 patients, and facilitated 30 bone marrow transplants. For more information, call (323) 663-3609 or visit abmdr.am.

Original post:
Artsakh Soldier Saves Life Of Cancer Patient In Iran - Asbarez Armenian News

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See more here:
Stem cell therapies breaking barriers - Guardian (blog)

Times Now

'Custom-made' babies to be in demand in 30 years, says expert Times Now The process will involve taking a female skin sample to create stem cells, which is then used to create eggs. These eggs are then fertilised with sperm cells, resulting in a selection of embryos. While Greely does acknowledge that ethical issues could ... People will 'stop having sex to procreate within 30 years', says scientistMetro Sex Not Necessary for Reproduction: Stanford Professor's Prediction Suggests a Bizarre FutureIndia.com PLAYING GOD: 'End to sex' in 30 years as parents will DESIGN their babies in the labExpress.co.uk Christian Post -Deccan Chronicle all 11 news articles »

Continue reading here:
'Custom-made' babies to be in demand in 30 years, says expert - Times Now

This report describes and evaluates cell therapy technologies and methods, which have already started to play an important role in the practice of medicine. Hematopoietic stem cell transplantation is replacing the old fashioned bone marrow transplants. Role of cells in drug discovery is also described. Cell therapy is bound to become a part of medical practice.

Stem cells are discussed in detail in one chapter. Some light is thrown on the current controversy of embryonic sources of stem cells and comparison with adult sources. Other sources of stem cells such as the placenta, cord blood and fat removed by liposuction are also discussed. Stem cells can also be genetically modified prior to transplantation.

Cell therapy technologies overlap with those of gene therapy, cancer vaccines, drug delivery, tissue engineering and regenerative medicine. Pharmaceutical applications of stem cells including those in drug discovery are also described. Various types of cells used, methods of preparation and culture, encapsulation and genetic engineering of cells are discussed. Sources of cells, both human and animal (xenotransplantation) are discussed. Methods of delivery of cell therapy range from injections to surgical implantation using special devices.

Cell therapy has applications in a large number of disorders. The most important are diseases of the nervous system and cancer which are the topics for separate chapters. Other applications include cardiac disorders (myocardial infarction and heart failure), diabetes mellitus, diseases of bones and joints, genetic disorders, and wounds of the skin and soft tissues.

Regulatory and ethical issues involving cell therapy are important and are discussed. Current political debate on the use of stem cells from embryonic sources (hESCs) is also presented. Safety is an essential consideration of any new therapy and regulations for cell therapy are those for biological preparations.

The cell-based markets was analyzed for 2016, and projected to 2026. The markets are analyzed according to therapeutic categories, technologies and geographical areas. The largest expansion will be in diseases of the central nervous system, cancer and cardiovascular disorders. Skin and soft tissue repair as well as diabetes mellitus will be other major markets.

The number of companies involved in cell therapy has increased remarkably during the past few years. More than 500 companies have been identified to be involved in cell therapy and 306 of these are profiled in part II of the report along with tabulation of 291 alliances. Of these companies, 170 are involved in stem cells. Profiles of 72 academic institutions in the US involved in cell therapy are also included in part II along with their commercial collaborations. The text is supplemented with 64 Tables and 22 Figures. The bibliography contains 1,200 selected references, which are cited in the text.

Key Topics Covered:

Part I: Technologies, Ethics & Regulations

Executive Summary

1. Introduction to Cell Therapy

2. Cell Therapy Technologies

3. Stem Cells

4. Clinical Applications of Cell Therapy

5. Cell Therapy for Cardiovascular Disorders

6. Cell Therapy for Cancer

7. Cell Therapy for Neurological Disorders

8. Ethical, Legal and Political Aspects of Cell therapy

9. Safety and Regulatory Aspects of Cell Therapy

Part II: Markets, Companies & Academic Institutions

10. Markets and Future Prospects for Cell Therapy

11. Companies Involved in Cell Therapy

12. Academic Institutions

13. References

For more information about this report visit https://www.researchandmarkets.com/research/hpj9sh/cell_therapy

Source: Jain PharmaBiotech

Media Contact:

Laura Wood, Senior Manager press@researchandmarkets.com

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To view the original version on PR Newswire, visit:http://www.prnewswire.com/news-releases/global-cell-therapy-report-2017---technologies-markets-and-companies-2016-2026-with-profiles-of-key-companiesinstitutions-300483356.html

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Global Cell Therapy Report 2017 - Technologies, Markets and Companies 2016-2026 with Profiles of Key Companies ... - PR Newswire (press release)

It will provide Regenexx, a regenerative stem cells procedure to treat orthopedic and sports injuries.

Regenexx, a national network of musculoskeletal doctors specializing in the nations most advanced regenerative protocols for treating orthopedic conditions and sports injuries has entered in Mumbai. This is its second branch in Asia. It would offer two stem cell procedures using imaging and interventional orthopaedic techniques to non-surgically repair and regenerate. The first one is a same-day procedure where stem cells are harvested, isolated and re-implanted on the same day. The second one is blood-derived plasma-rich platelet procedure. They would help athletes and non-athletes overcome early, mild, moderate ortho problems in a way that is devoid of surgery.

Regenexx is the most advanced stem cell and platelet procedures for treating orthopedic injuries, arthritis and other degenerative conditions. These procedures offer non-surgical alternatives to commonly occurring musculoskeletal conditions. PatentedRegenexx procedures use precise injections of your own stem cells or blood platelets to help your body's ability to heal damaged muscles, tendons, ligaments, cartilage, spinal disc and bone.Regenexx Stem Cell Therapy and Platelet Procedures, avoid the need for invasive surgery, in turn eliminating any complications that are typically seen with surgeries.

On this occasion Dr.Venkatesh Movva, MD, Regenexx India says,The only option till now was total knee replacement. Now with this technology we can heal and regenerate the lost tissues like cartilage, meniscus and ligaments to reverse the arthritis and in turn avoid any major surgery. Patients return to their loved activities in no time. We could also treat conditions like lower back pain, hip arthritis, bulging discs, ankle and shoulder rotator cuff tears with stem cells orthopedics procedure. Majority of these are lifestyle related conditions,

Regenexx procedures are image guided needle based procedures, so the downtime for recovery is minimal or none. These are truly ambulatory procedures without the need for hospitalization. The procedure process involves harvesting bone marrow stem cells, using our sophisticated lab process to separate cells and precise image guided injections into the target joints in an outpatient setting.

Dr. Apurv Mahalle, MGIMS, says, Regenexx procedures are out-patient procedures and that patients can walk out of the treatment the same day. Physiotherapy team at Regenexx will help patients make the necessary changes to their physical movements so that the procedures are effective.

There is no alternative for arthritis patients but to wait until the joint is bad enough for a replacement and then go through a surgery. Regenexx procedures are going to help these patients get back to the normal routine without the necessity of a replacement surgery.

Original post:
RegenOrthoSport facility launched in Mumbai - BSI bureau (press release)

MIRI: The second child cancer survivor I met, Winnie Foo Hui Yii, is an encouraging story and a living proof to the community how blood stem cell transplantation could help cancer patients.

Foo, born and raised in Kuching, was 17 years old when she was diagnosed with Acute Myeloid Leukaemia (AML).

The news was definitely not something Foo and her family would have expected as she was then studying A-Level.

I looked very pale, felt drowsy, nauseous and always felt tired. It persevered for three weeks before my parents suggested a check-up with our family doctor, she said, sharing her experience with The Borneo Post during a visit to Miri recently.

A blood test, she said, showed she had AML and before she could prepare herself for anything that followed, she was already warded in Sarawak General Hospitals haematology ward and in queue for chemotherapy in two weeks time.

Thereafter, she was transferred to Hospital Ampang, one of the 11 haemopoietic transplant centres performing haemopoietic stem cell transplants in Malaysia.

The doctor told me that though my condition was at the edge of turning cancerous, there was still hope for treatment and best, a transplant. I was in a state of shock. So were my parents. They too werent prepared for anything like this.

Honestly, at first my mind kept recalling a book My Sisters Keeper that Id just finished reading right before I was diagnosed. The novel tells the story of a main character, Anna, and her sister who was suffering from leukaemia.

After my diagnosis, I really felt the dying sisters feeling and facing death isnt easy, especially for parents.

While she was on cycles of chemotherapy, her family members were tested for possibility as matching bone marrow donor.

Unfortunately, there was no match and her parents decided to seek another option.

My doctor suggested stem cell transplant, a transplant of blood-forming stem cells to restore the bone marrow. We were given option whether to search in China or Taiwan. We saw hope, however, not without expecting huge expenses, Foo said.

At the time, Taiwan seemed to be the best hope for Foo to find a matching donor, who her doctor had targeted at least 60 per cent of compatibility. A total of seven matching donors were found over the span of three months since search begun, which was splendid news for them.

Being a middle-income family, the expenses for the transplant that cost tens of thousands of ringgit were too much for my parents to bear.

It was said that if the donor happened to be amongst the patients family members, part of the cost would be covered by the government. In Foos case, she had no other choice but to seek a donor internationally.

That was when Sarawak Childrens Cancer Society stepped in to assist Foo and her family, financially and on moral support.

Before the transplant, Foo underwent rounds of chemotherapy that used higher doses of medication and radiation therapy to kill the cancer cells. The final round of chemo right before the transplant was intended to get rid of the bodys immune system, getting the body ready.

The chemotherapy resulted in Foos hair dropping severely to baldness. Initially, she felt the physical changes were interesting, however, not long after, she missed her hair terribly, but tried to put up a brave face.

After the transplant, Foo experienced post-transplant rejection, which according to her doctor is a condition known as immuno-suppression. She was put under doctors observation and prescribed medication such as steroid to stabilise her condition.

My doctor told me that after transplant, my bodys immune system was not quite ready yet. Eventually, it turned out okay for me, she said.

Now, at the age of 21 and on the road to recovery, Foo has restarted her A-Level and is now in her second year.

Looking back at these three years, it taught me a lot about life and to be appreciative. My first day back to school wasnt easy for me because I was the oldest amongst my course-mates. Handling stares is the hardest part but I managed to overcome it.

My parents went through a lot during that period. Apart from enduring the emotional roller-coaster, they made sure that I was well taken care of and not emotionally affected by my own condition. For that, I am so thankful to them.

I guess I managed my emotion well in front of them too, though I would sometimes feel so helpless and weak and at times feeling angry on why things like this happen to me.

But many a times, I told myself that I can do it, because I am still young and have the energy and time to battle against the sickness in me, Foo said.

When she isnt busy with her studies, Foo would spare her time to volunteer with SCCS.

These children with cancer, though some of them may have been in the ward for a long time, they look cheerful.

Being a volunteer, spending time with them, has taught me to be more empathetic, to be content with simple things and that there are many things in life that are more precious. Life is too short to burden yourself with negative thoughts.

This year, Foo has planned to have her head shaved in the coming Kuching leg of Go Bald campaign that will be held on July 9 at CityOne Megamall.

Stem Cell Donor Awareness campaign

President of SCCS, Jocelyn Hee, said the awareness on stem cell donation in the country, particularly Sarawak, is still at a very low level.

This is a new effort taken by SCCS to give hope and save lives of these cancer-stricken children as well as their family, Hee told The Borneo Post.

According to statistics by Malaysian Stem Cell Registry (MSCR), there are 28,500 registered volunteers and only 372 of them are of Sarawak ethnicity.

It is important to know that the diversity of race and intermarriage among Malaysians is one of the contributing factors to the low probability of finding a matching donor for a patient.

Hence, she said, an awareness campaign on stem cell is the initial step theyve taken to call on more donors.

Sarawakians are highly encouraged to pledge as blood stem cell donors, to increase the percentage in finding a compatible donor for patients from Sarawak.

Stem Cell Donor Awareness Drive and Talk will be held at CityOne Megamalls main stage on July 8 from 1.45pm to 2.30pm.

The talk will be sharing information on how stem cell donor-ship helps cancer patients, how one can be eligible to be a donor and the process to become one.

We hope that more people could come and support the good cause, and to spread the word to every member of the society, Hee said.

Link:
Cancer survivor shares how she was saved by stem cell transplant - The Borneo Post