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FAQ Part 2: MEsenchymal Stem cell therapy for CAnadian MS patients (MESCAMS) – Video

By NEVAGiles23


FAQ Part 2: MEsenchymal Stem cell therapy for CAnadian MS patients (MESCAMS)
The Multiple Sclerosis Society of Canada and the Multiple Sclerosis Scientific Research Foundation have announced a $4.2 million grant in support of the MEsenchymal Stem cell therapy for CAnadian.

By: MSSocietyCanada

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FAQ Part 2: MEsenchymal Stem cell therapy for CAnadian MS patients (MESCAMS) - Video

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Knee arthritis; 2 years after stem cell therapy by Harry Adelson, N.D. – Video

By daniellenierenberg


Knee arthritis; 2 years after stem cell therapy by Harry Adelson, N.D.
Patricia describes her outcome two years after bone marrow and adipose stem cell therapy for her arthritic knee by Harry Adelson, N.D. http://www.docereclinics.com.

By: Harry Adelson, N.D.

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Hospital pioneers Magneto-style stem cell surgery

By raymumme

HIROSHIMA In a world first, a team at Hiroshima University Hospital on Friday conducted regenerative knee surgery using a technique that employs magnets to concentrate iron-laced stem cells around damaged cartilage, it said.

The endoscopic surgery is less arduous for the patient, said the team led by Mitsuo Ochi, a professor at the hospital. Conventional treatment requires two operations to repair cartilage.

It will take at least a year to determine the effectiveness of the regenerative technique, though previous tests on animals have proven successful, it said.

The team plans to conduct further operations to reaffirm the regenerative surgerys safety in clinical research.

In the operation, the team extracted mesenchymal stem cells from bone marrow of an 18-year-old female high school student and cultivated them with a dash of iron powder to create magnetic stem cells that can develop into various tissues.

The team injected the iron-laced stem cells into the patients right knee joint and used the magnet to concentrate them in areas where cartilage was lost. The stem cells are expected to develop into cartilage.

Cartilage absorbs shock and reduces friction between bones so everything moves smoothly, but its regenerative abilities are limited.

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Laying a foundation for treating ALS, spinal cord injury

By NEVAGiles23

Feb. 2, 2015

Su-Chun Zhang (center), a UW professor of neuroscience, talks with staff in his lab as they prepare stem cell cultures in March 2013.Zhangs new research may lay the foundation for treating neurodegenerative diseases like ALS.

Photo: Jeff Miller

This story starts in 1955, upon the death of Albert Einstein, when the pathologist charged with performing the famous scientists autopsy stole his brain.

Fast forward to the 1980s when a University of California, Berkeley scientist was studying parts of the stolen goods involved in complex thinking and discovered that the father of relativity had more of certain types of cells, called astrocytes, than other human brains studied.

Today, another 30 years later, scientists still dont have a solid grasp on everything these cells do in the human nervous system, largely because theyre difficult to study. But Su-Chun Zhang, a professor of neuroscience and neurology at the University of Wisconsin-Madison Waisman Center, and his research team have published a unique model for learning more about the role of human astrocytes in the Journal of Clinical Investigation today.

Su-Chun Zhang

The findings may lay a foundation for the treatment of a number of neurodegenerative diseases, including ALS (amyotrophic lateral sclerosis) and debilitating spinal cord injuries.

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Cardiac Stem Cell Therapy May Heal Heart Damage Caused by …

By NEVAGiles23

Late-Breaking Basic Science Research Presented at American Heart Association Scientific Sessions Shows Stem Cell Treatment Restores Heart Function Damaged by Muscular Disease

Contact: Sally Stewart Email: sally.stewart@cshs.org

Los Angeles - Nov. 17, 2014 Researchers at the Cedars-Sinai Heart Institute have found that injections of cardiac stem cells might help reverse heart damage caused by Duchenne muscular dystrophy, potentially resulting in a longer life expectancy for patients with the chronic muscle-wasting disease.

The study results were presented today at a Breaking Basic Science presentation during the American Heart Association Scientific Sessions in Chicago. After laboratory mice with Duchenne muscular dystrophy were infused with cardiac stem cells, the mice showed steady, marked improvement in heart function and increased exercise capacity.

Duchenne muscular dystrophy, which affects 1 in 3,600 boys, is a neuromuscular disease caused by a shortage of a protein called dystrophin, leading to progressive muscle weakness. Most Duchenne patients lose their ability to walk by age 12. Average life expectancy is about 25. The cause of death often is heart failure because the dystrophin deficiency leads to cardiomyopathy, a weakness of the heart muscle that makes the heart less able to pump blood and maintain a regular rhythm.

"Most research into treatments for Duchenne muscular dystrophy patients has focused on the skeletal muscle aspects of the disease, but more often than not, the cause of death has been the heart failure that affects Duchenne patients," said Eduardo Marbn, MD, PhD, director of the Cedars-Sinai Heart Institute and study leader. "Currently, there is no treatment to address the loss of functional heart muscle in these patients."

During the past five years, the Cedars-Sinai Heart Institute has become a world leader in studying the use of stem cells to regenerate heart muscle in patients who have had heart attacks. In 2009, Marbn and his team completed the world's first procedure in which a patient's own heart tissue was used to grow specialized heart stem cells. The specialized cells were then injected back into the patient's heart in an effort to repair and regrow healthy muscle in a heart that had been injured by a heart attack. Results, published in The Lancet in 2012, showed that one year after receiving the experimental stem cell treatment, heart attack patients demonstrated a significant reduction in the size of the scar left on the heart muscle.

Earlier this year, Heart Institute researchers began a new study, called ALLSTAR, in which heart attack patients are being infused with allogeneic stem cells, which are derived from donor-quality hearts. Recently, the Heart Institute opened the nations first Regenerative Medicine Clinic, designed to match heart and vascular disease patients with appropriate stem cell clinical trials being conducted at Cedars-Sinai and other institutions.

"We are committed to thoroughly investigating whether stem cells could repair heart damage caused by Duchenne muscular dystrophy," Marbn said.

In the study, 78 lab mice were injected with cardiac stem cells. Over the next three months, the lab mice demonstrated improved pumping ability and exercise capacity in addition to a reduction in heart inflammation. The researchers also discovered that the stem cells work indirectly, by secreting tiny fat droplets called exosomes. The exosomes, when purified and administered alone, reproduce the key benefits of the cardiac stem cells.

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Human stem cells repair damage caused by radiation therapy for brain cancer in rats

By daniellenierenberg

For patients with brain cancer, radiation is a powerful and potentially life-saving treatment, but it can also cause considerable and even permanent injury to the brain. Now, through preclinical experiments conducted in rats, Memorial Sloan Kettering Cancer Center researchers have developed a method to turn human stem cells into cells that are instructed to repair damage in the brain. Rats treated with the human cells regained cognitive and motor functions that were lost after brain irradiation. The findings are reported in the February 5 issue of the journal Cell Stem Cell.

During radiation therapy for brain cancer, progenitor cells that later mature to produce the protective myelin coating around neurons are lost or significantly depleted, and there is no treatment available to restore them. These myelinating cells--called oligodendrocytes--are critical for shielding and repairing the brain's neurons throughout life.

A team led by neurosurgeon Viviane Tabar, MD, and research associate Jinghua Piao, PhD, of the Memorial Sloan Kettering Cancer Center in New York City, wondered whether stem cells could be coaxed to replace these lost oligodendrocyte progenitor cells. They found that this could be achieved by growing stem cells--either human embryonic stem cells or induced pluripotent stem cells derived from skin biopsies--in the presence of certain growth factors and other molecules.

Next, the investigators used the lab-grown oligodentrocyte progenitor cells to treat rats that had been exposed to brain irradiation. When the cells were injected into certain regions of the brain, brain repair was evident, and rats regained the cognitive and motor skills that they had lost due to radiation exposure. The treatment also appeared to be safe: none of the animals developed tumors or inappropriate cell types in the brain.

"Being able to repair radiation damage could imply two important things: improving the quality of life of survivors and potentially expanding the therapeutic window of radiation," said Dr. Tabar. "This will have to be proven further, but if we can repair the brain effectively, we could be bolder with our radiation dosing, within limits." This could be especially important in children, for whom physicians deliberately deliver lower radiation doses.

Story Source:

The above story is based on materials provided by Cell Press. Note: Materials may be edited for content and length.

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Advanced stem cell treatments instead of surgery – Denver Regenerative Medicine – Video

By LizaAVILA


Advanced stem cell treatments instead of surgery - Denver Regenerative Medicine
If you #39;re tired of treating a chronic injury with prescription drugs, and you #39;ve been told surgery is your next option, there may be a different treatment for you. Dr. Joel Cherdack of...

By: Denver Regenerative Medicine

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Neck and Shoulder arthritis two years after stem cell therapy by Harry Adelson, N.D. – Video

By JoanneRUSSELL25


Neck and Shoulder arthritis two years after stem cell therapy by Harry Adelson, N.D.
Steve describes his outcome two years after stem cell therapy for his arthritic neck and shoulder by Dr Harry Adelson http://www.docereclinics.com.

By: Harry Adelson, N.D.

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Okyanos Cell Therapy Success Brings Hope for a Normal Life

By Dr. Matthew Watson

Freeport, Grand Bahama (PRWEB) February 04, 2015

In just a few short months since Okyanos opened its doors, remarkable results are becoming a daily reality. In light of these mounting successes, Okyanos, the leader in cell therapy, has augmented its adult stem cell therapy for severe heart disease and expanded their offerings to include treatments for patients with other chronic unmet needs. Now, patients like Patsy and Dylan are experiencing the tangible benefits that Okyanos cell therapy provides.

Patsy, 72 years old, lived a normal life until 2012 when a diagnosis of congestive heart failure (CHF) put a halt to her active lifestyle. Patsys health quickly deteriorated. Despite open heart surgery, a pacemaker and medications, all were insufficient to arrest her physical decline. Faced with a heart transplant as her next option and fearful of the idea, Patsy began searching for another alternative.

I was looking at going to Mexico, and my cardiologist was talking to me about being a part of a clinical trial where they inject two different kinds of drugs into the heart, but I was hesitant about that idea and worried I would get the placebo. A friend knew I had a heart problem, and she recommended Okyanos.

Patsys arrival at Okyanos quickly allayed any apprehension as she said, I couldnt ask to be treated any better than if they were my own sisters or brothers. It was truly amazing. You just dont get that kind of care in regular hospitals.

After just a few short months since her mid-October (2014) treatment with Okyanos cell therapy, Patsy is noticing improvements. Im doing better. I can already tell the difference. Im getting up the stairs more easily. Im doing the laundry again. I have more energy, and when you have more energy and you feel better, your point of view on life is betterit really makes a big difference.

Dylan is another success. At 16, Dylan had dreamt of a career playing tennis but began experiencing extreme pain with his hips locking up, causing him to fall to the ground. He was diagnosed with a rare condition that causes abnormal growth of tissue lining the joints that can later break off and damage cartilage. After 2 surgeries to clean out his hips, constant pain and an inability to walk without a limp, run or bend over, the condition worsened. After speaking with doctors, it was clear that continuation of regular surgeries would further deteriorate Dylans hips. Determined to see her son walk normally, Dylans mother discovered Okyanos and both decided to move forward with cell therapy.

Dylan underwent cell therapy wherein stem cells were separated from his own fat tissue for direct injections into the hip as well as delivery by IV to address underlying causes of ischemia, inflammation and abnormal immune response. Ten days later, Dylan was pain-free and able to walk normally, run and bend over.

Im pinching myself. Its amazing. No, its miraculous! says Elena about her sons recovery. If Dylan had not had the cell therapy, we would have kept doing other treatments and crossed our fingers. At 20 years old, his future would have been hip replacement surgery and a lifetime of problems walking, painful movement and an inability to bend down.

Stem cell therapy is a relatively simple and minimally-invasive same-day procedurea stark contrast from open heart surgery or hip surgeryyet offers patients the hope of a more normal life. Patients like Patsy concur, Its going to give people hope. And give them a life. You get to a point with a body where you push and push and run out of energy. Thats not really life to me. I think stem cell therapy can give back life.

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Florida Panther Receives Cutting Edge Stem Cell Procedure from MediVet Biologics

By JoanneRUSSELL25

Nicholasville, KY (PRWEB) February 04, 2015

Rescued when he was only 4 weeks old, Nakiia, a 15-year-old Panther, has been living in severe pain after a jumping incident. Jan Hall, Nakiias owner has dedicated her life to rescuing animals. Nakiia, the namesake of her rescue foundation The Nakiia Foundation is the love of her life. Witnessing this fabulous animal in such pain was too much for Jan to bear. The Doctors treating Nakiia decided to undertake a revolutionary medical procedure, which centers on regenerative medicine.

Newman Veterinary Center in DeLand Florida performed MediVets Adipose (fat)-derived stem cell therapy. The male Florida panther underwent this procedure, more commonly performed on domestic animal such as dogs, cats and horses. The procedure is an effort to ease the pain from severe arthritis in his joints. This was a last stage effort for the panther that can no longer continue to live in such pain.

Though stem cell treatments have been performed in exotic animals before, it is still a rare and exciting undertaking. Utilizing MediVet Biologics procedure, Dr. Ted Oliver was able to ensure the process will produce the best possible results. MediVets procedure is completed in one day and in-clinic.

Stem Cell treatments in the past have often been controversial when embryonic cells where involved, with adipose or fat tissue Nakiias own adult stem cells could be easily concentrated and activated with minimal risk. Until recently Veterinarians only had the option of utilizing outside labs for processing of autologous cells, with the one step surgical treatment available from MediVet Biologics, Veterinarians all around the country can eliminate the costs and variability in shipping by utilizing an onsite simple procedure.

During the procedure, Dr. Oliver removed about four tablespoons of belly fat from the panther. The fat was then processed in-clinic by a trained technician. The cells are incubated, isolated and activated by a patented process. Dr. Oliver carefully re-administered the cells directly back into Nakiia. Nakiias excess cells will be stored for future use eliminating the need to surgically re-harvest additional tissue.

MediVets primary mission and goal is to help all animals live a pain free life. In regenerative medicine and biologic intervention age is not a disease rather a challenge that presents us many opportunities to develop cutting edge treatments to combat issues related to the aging process. Our partnerships with progressive Veterinarians such as Newman Veterinary Centers allow us to extend affordable cutting edge treatments to animals who otherwise potentially have limited treatments available. We look forward to following Nakiias progress." - Jeremy Delk, CEO of MediVet Biologics.

Newman Veterinary Center was honored to be a part of Nakiias stem cell procedure. The excitement that this 146-lb. cat brought to our clinic was unparalleled. We have very high hopes that Nakiia will be feeling much better very soon. - Erica Kent Director of Operations at Newman Veterinary Centers.

Nakiias story will air on Wednesday, February 4th on CBS WKMG (local 6) with Mike Holfeld, Investigative Reporter.

About MediVet Biologics MediVet Biologics is the Worlds leading provider of Veterinary regenerative medicine. The central Kentucky based company was founded in 2009 and quickly gained favor in the Veterinary industry with the advent of in-clinic adipose derived stem cell and platelet rich plasma treatments. Since gaining wide appeal in the small and large veterinary market MediVet Biologics has developed a strong biologic pipeline that includes, among other cutting edge treatment options, patient specific immunotherapy services.

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A few cells could prevent bone marrow transplant infections

By raymumme

Bone marrow transplantation is a life-saving therapy for patients with blood cancers like leukemia or lymphoma. However, the depletion of the patient's immune system prior to transplantation can put patients at risk of for an infection by a virus called cytomegalovirus (CMV) that can be life threatening in these immune-compromised individuals. Now, researchers have found that a very small subset of anti-viral immune cells, transplanted along with a donor's blood stem cells, could be enough to fight and even prevent the disease caused by CMV, in research conducted in mice and published Jan 16th in the Journal of Immunology.

Anywhere between 50-80 percent of adults in the United States are infected with CMV, although the virus is kept under control by a healthy immune system. In patients with weakened immune systems, however, CMV can become reactivated and can cause life-threatening pneumonia, among other symptoms. Current treatment includes antiviral medication, but these are not always well tolerated by patients and they also harm the very cells that bone marrow transplantation aims to replenish.

"We know that re-establishment of anti-viral immunity in these patients is critical to fully control cytomegalovirus in bone marrow transplant recipients," says senior author Christopher Snyder, Ph.D., an Assistant Professor of Microbiology and Immunology at Thomas Jefferson University. "Our study suggests that, in addition to infusing stem cells that restore the bone marrow, life-long anti-CMV immunity may be rapidly restored by also infusing a subset of anti-viral immune cells that have stem cell-like properties."

Currently, investigators around the world are experimenting with restoring the immune cells responsible for keeping CMV in check by transplanting those specific anti-viral cells from healthy donors -- a type of immunotherapy. "The problem," says Dr. Snyder, "is that current methods for selecting anti-viral immune cells may inadvertently limit the ability of those cells to restore life-long immunity."

To date, researchers have focused on developing anti-CMV immunotherapy around the "fighter" cells -- called CD8 T effector cells -- that attack and kill virally-infected host cells. These cells are selected and expanded in the lab to increase their numbers, but this process may limit their life-span and ability to divide.

Dr. Snyder and colleagues found that CMV-specific fighter T cells divided poorly in response to CMV infection or reactivation in mouse models. They hypothesized that a different type of CD8 T cells -- one that acts more like a stem cell -- could help control the infection long term. His group showed that a small number of stem-cell like CD8 T cells -called "memory" cells -were enough to produce and repeatedly replenish all of the T-effector cells needed to fight the disease. The infused memory cells became major contributors to the recipient anti-viral immune response, persisting for at least 3 months of time and producing the "fighter" cells at a steady stream.

In order to survey whether these cells have counterparts in humans, the researchers compared the genomic fingerprint -- the profile of genes that were turned up or down -- of mouse and human memory T cells that were specific for CMV and found that the two had similar profiles. "This suggested that human and mouse CMV-specific memory T cells are very similar populations. Therefore infusing similar cells into humans could improve on immunotherapeutic methods for controlling CMV infection," said first author Michael Quinn MD/PhD student in the Department of Microbiology and Immunology at Thomas Jefferson University. "This may be a valuable approach to keep the disease from emerging in people."

"Our data argue for developing new clinical trials focused specifically on using these T memory cells, in order to determine if it would indeed be better than current therapeutic options," said Dr. Snyder.

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The above story is based on materials provided by Thomas Jefferson University. Note: Materials may be edited for content and length.

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The Miami Stem Cell Treatment Center Announces Adult Stem Cell Public Seminars in The Villages, Florida

By raymumme

The Villages, Florida (PRWEB) February 03, 2015

In honor of our new location in The Villages, the Miami Stem Cell Treatment Center announces a series of free public seminars on the use of adult autologous stem cells for various degenerative and inflammatory conditions. They will be provided by Dr. Thomas A. Gionis, Surgeon-in-Chief and Dr. Nia Smyrniotis, Medical Director and Surgeon.

The seminars will be held on Tuesday, February 17, 2015, at 10:00am at the La Hacienda Regional Recreation Center, 1200 Avenida Central, The Villages, FL 32159, and at 1:00pm and 3:00pm on February 17th and 1:00pm, 3:00pm and 5:00pm on March 3rd at the Holiday Inn Express and Suites, The Villages, 1205 Avenida Central, The Villages, FL 32159. There will also be a Social Hour with the Doctors at 7:00pm on February 17th and March 3rd at the City Fire American Oven & Lounge at Brownwood (Paddock Square), 2716 Brownwood Blvd., The Villages, FL 32163. Please RSVP for ALL events is mandatory at (561) 331-2999.

Dr. Gionis has been graciously invited to speak to the local MS support group at the 10:00am seminar on February 17 which will be held at the La Hacienda Regional Recreation Center.

The Miami Stem Cell Treatment Center (Miami; Boca Raton; Orlando; The Villages), along with sister affiliates, the Irvine Stem Cell Treatment Center (Irvine; Westlake Villages, California) and the Manhattan Regenerative Medicine Medical Group (Manhattan, New York), abide by approved investigational protocols using adult adipose derived stem cells (ADSCs) which can be deployed to improve patients quality of life for a number of chronic, degenerative and inflammatory conditions and diseases. ADSCs are taken from the patients own adipose (fat) tissue (found within a cellular mixture called stromal vascular fraction (SVF)). ADSCs are exceptionally abundant in adipose tissue. The adipose tissue is obtained from the patient during a 15 minute mini-liposuction performed under local anesthesia in the doctors office. SVF is a protein-rich solution containing mononuclear cell lines (predominantly adult autologous mesenchymal stem cells), macrophage cells, endothelial cells, red blood cells, and important Growth Factors that facilitate the stem cell process and promote their activity.

ADSCs are the bodys natural healing cells - they are recruited by chemical signals emitted by damaged tissues to repair and regenerate the bodys injured cells. The Miami Stem Cell Treatment Center only uses Adult Autologous Stem Cells from a persons own fat No embryonic stem cells are used; and No bone marrow stem cells are used. Current areas of study include: Emphysema, COPD, Asthma, Heart Failure, Heart Attack, Parkinsons Disease, Stroke, Traumatic Brain Injury, Lou Gehrigs Disease, Multiple Sclerosis, Lupus, Rheumatoid Arthritis, Crohns Disease, Muscular Dystrophy, Inflammatory Myopathies, and degenerative orthopedic joint conditions (Knee, Shoulder, Hip, Spine). For more information, or if someone thinks they may be a candidate for one of the adult stem cell protocols offered by the Miami Stem Cell Treatment Center, they may contact Dr. Gionis or Dr. Smyrniotis directly at (561) 331-2999, or see a complete list of the Centers study areas at: http://www.MiamiStemCellsUSA.com.

About the Miami Stem Cell Treatment Center: The Miami Stem Cell Treatment Center, along with sister affiliates, the Irvine Stem Cell Treatment Center and the Manhattan Regenerative Medicine Medical Group, is an affiliate of the California Stem Cell Treatment Center / Cell Surgical Network (CSN); we are located in Boca Raton, Orlando, Miami and our new office in The Villages, Florida. We provide care for people suffering from diseases that may be alleviated by access to adult stem cell based regenerative treatment. We utilize a fat transfer surgical technology to isolate and implant the patients own stem cells from a small quantity of fat harvested by a mini-liposuction on the same day. The investigational protocols utilized by the Miami Stem Cell Treatment Center have been reviewed and approved by an IRB (Institutional Review Board) which is registered with the U.S. Department of Health, Office of Human Research Protection (OHRP); and our studies are registered with Clinicaltrials.gov, a service of the U.S. National Institutes of Health (NIH). For more information, visit our websites: http://www.MiamiStemCellsUSA.com, http://www.IrvineStemCellsUSA.com , or http://www.NYStemCellsUSA.com.

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US Orthopedic Biomaterials Market Examined by iData Research in In-demand Report Now Available at MarketPublishers.com

By Dr. Matthew Watson

London, UK (PRWEB) February 03, 2015

Over the next few years, the stem cells market is poised to continue to be the most rapidly growing segment, which includes the segments for concentrated bone marrow and stem cell bone grafts. Stem cells provide greater osteogenesis and osteoinductive properties than other bone grafts, and thus enhance bone repair. To date, their usage is only considered for the treatment of spine cord injuries, but the market is likely to witness further expansion in case other indications are approved, such as with the foot where a number of patients may experience poor vascularisation.

The orthopedic biomaterials market in the USA is forecast to gain traction through 2021. The ageing population is a key factor driving the market. In tandem with the surging ageing population, the incidence rates of osteoarthritis and other types of degenerative disorders are also expected to grow, thus driving the demand for orthopedic biomaterials. Additionally, a huge portion of the overall biomaterial products market is engaged in treating soft tissue injuries, and most of them are sport-related. However, high costs of the development of some products could hinder the sectors growth. Furthermore, the timeliness of a products final approval is often hard to foretell.

Medtronic dominated the orthopedic biomaterials market as of 2014, due to the lions share of the bone graft substitute sector. The company announced in June 2014 its intention to buy Covidien for USD 42.9 billion.

In-demand study U.S. Orthopedic Biomaterials Market worked out by iData Research has been recently published at MarketPublishers.com.

Report Details:

Title: U.S. Orthopedic Biomaterials Market Published: January, 2015 Pages: 288 Price: US$ 6,995.00 http://marketpublishers.com/report/medical_devices/orthopedic/us-orthopedic-biomaterials-market.html

The research report contains an all-encompassing analysis and forecast of the orthopedic biomaterials market across the USA up to 2021. It provides detailed market analyses of leading market segments, including bone graft substitutes, hyaluronic acid viscosupplementation, orthopedic stem cells, growth factors, cartilage repair, cell therapy, and machined bone allografts; the categories are further subdivided into subcategories by various parameters. The study identifies the game-changing opportunities and potential hazards in the market, traces the key trends and technologies expected to impact the overall market and each of its individual segments in the years to come, as well as sheds light on the market drivers and restraints. Essential information on the number of procedures is provided. Furthermore, the research study canvasses the competitive landscape as well as discusses the top 22 companies along with their success strategies, M&As, etc.

Report Scope:

More in-demand reports by the publisher can be found at iData Research page.

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US Orthopedic Biomaterials Market Examined by iData Research in In-demand Report Now Available at MarketPublishers.com

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Gordie Howe recovering from stroke after stem-cell transplant

By NEVAGiles23

Gordie Howe is making a remarkable recovery from a stroke that nearly led to him being placed in hospice care last fall.

The hockey great has gained 20 pounds and is doing fantastic after undergoing stem-cell treatment in Mexico in early December, one of his sons told NHL Live. Howe continues to recover at the Lubbock, Texas, home of his daughter.

Hes doing very, very well, said Dr. Murray Howe, director of sports medicine imaging of Toledo Hospital. He has good days and bad days like anybody whos 86, but overall hes heading in the right direction really every day, a little bit better. He had his stem cell treatment Dec. 8 and really since that time hes just been doing fantastic.

He loves to be busy. If you want to torture him just make him sit down and watch television. He is just about doing stuff. Hes in great spirits. He has an excellent quality of life. Hes doing all the things that he wants to do now other than fishing, only because we havent taken him fishing since his treatment, but hes looking forward to doing that.

Howe was unable to stand, walk or feed himself after suffering the stroke in late October. He was losing weight because he wasnt able to sustain himself in terms of eating, his son said. He essentially got to the point where he was bedridden and it was just no quality of life there.

Although it was feared that he had suffered another stroke in early December, he was suffering from dehydration, but his family was told to consider hospice care. At around the same time, a San Diego biopharmaceutical company reached out to offer treatment at no charge. According to Howes son, the results were instant. From NHL.coms Jon Lane:

Gordie Howe had the treatment Dec. 8 in Tijuana at a Mexican stem cell company called Novastem thats licensed the use of Stemedicas cells for clinical trials approved by the Mexican government. Neural stem cells were injected into the spinal canal on Day 1 and mesenchymal stem cells by intravenous infusion on Day 2, according to a release sent by the Howe family in mid-December.

They said that we might see some changes in my father within 24 hours and I just didnt believe it, Dr. Howe said.

Eight hours later, Gordie Howe began talking. He then demanded to walk to the bathroom.

I said Ill get the urinal because you cant walk and he says, Well the [heck] I cant walk, Dr. Howe said. We actually sat up and put his feet down on the side of bed and I was absolutely stunned. Id never seen anything like it in 28 years of doing medicine.

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Gordie Howe recovering from stroke after stem-cell transplant

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Topeka Zoo Black Bear Undergoes Stem Cell Therapy

By JoanneRUSSELL25

Peek the American black bear (Courtesy: Topeka Zoo)

Peek the bear is shown undergoing a CT scan at St. Francis Health Center in this photo from the Topeka Zoo.

St. Francis Health Center staff watch as a CT scan is performed on Peek the black bear. (Courtesy: Topeka Zoo)

TOPEKA, Kan. (WIBW) - An American black bear at the Topeka Zoo may be the first bear ever to undergo stem cell treatment for a spinal problem.

Zoo Director Brendan Wiley says Peek, who is 20-years old, started losing control of her hind legs two weeks ago. The condition worsened and zoo staff says pain medication was not having any impact on the situation.

One of the unique things about this scenario is that Peek hasnt acted like anything is hurting her. It is like the front half of her body can no longer communicate with the back half, said Animal Care Supervisor Shanna Simpson.

The zoo worked with St. Francis Health Center to perform a CT scan. Peek was tranquilized and transported to St. Francis' imaging facilities.

"Our first priority is human patient safety and access," says Brent Wilkins, director of Imaging Services at St. Francis Health. "We work with the Topeka Zoo to accommodate animals that need CT scans in off hours when one of our CT scanners is available. We made sure the bear was separated from any other patients and performed a high-level decontamination and cleaning of the area, called a terminal cleaning, after the bears visit."

The scan revealed an area of Peek's spine with spinal stenosis, a narrowing of her spinal column, causing pressure on the spinal cord.

In anticipation of future treatment, Dr. Larry Snyder and Dr. Travis Gratton, veterinarians from Topeka's University Small Animal Hospital were contacted. Before Peek was transported for the CT scan, the two harvested fat cells, which they converted to stem cells to inject back into her. The theory behind the treatment is that the stem cells can stimulate damaged area to repair and heal itself.

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Topeka Zoo Black Bear Undergoes Stem Cell Therapy

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Topeka Zoo's bear gets CT scan, stem cell therapy

By daniellenierenberg

Peek, a 20-year-old American Black Bear living at the Topeka Zoo, is undergoing treatment, including a CT scan, for a back condition, zoo director Brendan Wiley said Monday.

Peek came out of her den two weeks ago and her keeper noticed the bears hind legs were wobbly. Peek was given pain medication. However, the condition quickly worsened, Wiley said in a news release.

Within the next seven days, Peek continued to lose control of her rear legs.

One of the unique things about this scenario is that Peek hasnt acted like anything is hurting her, said Shanna Simpson, animal care supervisor. It is like the front half of her body can no longer communicate with the back half.

Peeks illness required the use of a CT scan, which used equipment the zoo doesnt have, Wiley said.

Zoo veterinarian Shirley Llizo brought in Larry Snyder and Travis Gratton, of University Bird and Small Animal Hospital, to help harvest fat cells from Peek. This would allow the fat cells to be converted to stem cells to be injected.

Peek was tranquilized Jan. 22 and transported to the zoos hospital so the fat cells could be harvested. After the harvest, Peek was transported to St. Francis Health Center, where she was met by Brent Wilkins, director of imaging services, and his staff.

After confirming Peek would fit in the 72-centimeter CT scanner, Wilkins was able to do the scan, and radiologist James Owen found an area of Peeks spine was experiencing spinal stenosis. This is a narrowing of the spinal column that causes pressure on the spinal cord, according to zoo officials.

Our first priority is human patient safety and access, Wilkins said. We work with the Topeka Zoo to accommodate animals that need CT scans in off hours when one of our CT scanners is available. We made sure the bear was separated from any other patients and performed a high-level decontamination and cleaning of the area, called a terminal cleaning, after the bears visit. Were very happy to help our friends at the zoo in keeping the animals healthy.

After the CT scan, Peek went back to the zoo, where she received the stem cell therapy. Stem cell therapy treatment in bears is new technology, Wiley said.

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UCSD scientists awarded $2.7M grants for stem cell research

By daniellenierenberg

LA JOLLA (CNS) - Two scientists with UC San Diego were awarded a combined $2.7 million in grants from the California Institute for Regenerative Medicine to pursue their studies on stem cell therapies, the school announced Monday.

Shyni Varghese, an associate professor in the Department of Bioengineering and director of the Bio-Inspired Materials and Stem Cell Engineering Laboratory, received a $1.4 CIRM grant to improve the function of transplanted stem cells.

Shaochen Chen, a professor in the Department of Nanoengineering in the Jacobs School of Engineering and a member of UCSD's Institute of Engineering in Medicine, received $1.3 million to develop three-diminensional bioprinting techniques that use heart muscle cells derived from human embryonic stem cells to create new cardiac tissue.

The awards were part of almost $30 million in grants announced at CIRM's monthly meeting in San Francisco, according to UCSD.

"Sometimes even the most promising therapy can be derailed by a tiny problem," said Jonathan Thomas, chairman of the CIRM Board of Directors. "These awards are designed to help find ways to overcome those problems, to bridge the gaps in our knowledge and ensure that the best research is able to keep progressing and move out of the lab and into clinical trials in patients."

Varghese's lab focuses on the interactions of cells with their surrounding micro-environment, and how the conditions necessary to promote normal, healthy survival and growth occur, according to UCSD.

Chen's studies focus on using stem cells to create new heart tissue that would help patients when transplants aren't immediately available.

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Heard on the Street: Hormel Institute staffer gets $100,000 for cancer research

By raymumme

The Hormel Institute has announced Rebecca Morris, leader of the Stem Cells and Cancer research section, has received a one-year, $100,000 grant from the Minnesota Chemoprevention Consortium to study bone marrow-derived cells as potential new targets for preventing skin cancer.

The consortium includes the University of Minnesota's Hormel Institute, Mayo Clinic, the U of M's Masonic Cancer Center and Hormel Foods Consortium. The consortium goes by the moniker "MC^2."

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Heard on the Street: Hormel Institute staffer gets $100,000 for cancer research

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UCLA Researchers Receive Prestigious CIRM Tools and Technologies Award

By JoanneRUSSELL25

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Newswise Two scientists from the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have received a California Institute of Regenerative Medicine (CIRM) Tools and Technology Award that will forward revolutionary stem cell medicine. The UCLA researchers were among only 20 scientists nationwide to receive the Tools and Technologies Award, the most of any institution represented.

Recipients receiving awards for their respective projects included Dr. James Dunn, professor of bioengineering and surgery, for his research investigating skin-derived precursor stem cells for the treatment of enteric neuromuscular dysfunction, and Dr. Hanna Mikkola, associate professor of molecular, cell and developmental biology, for her work creating a suite of engineered human pluripotent stem cell lines to facilitate the generation of patient specific hematopoietic stem cells.

UCLA Broad Stem Cell Research Center Director Owen Witte said, We are very grateful for CIRMs support of these potentially groundbreaking projects intended to overcome significant bottlenecks in driving stem cell therapies to the clinic.

The CIRM Tools and Technologies initiative is designed specifically to support research that can address regenerative medicines unique translational challenges. The award seeks to facilitate the creation, design and testing of broadly applicable novel tools and technologies for addressing translational bottlenecks to stem cell therapies.

Dr. James Dunn: Unlocking the Secrets of Neuromuscular Dysfunction

Dr. Dunns cutting-edge work focuses on assessing the therapeutic potential of skin-derived stem cells to treat neuromuscular gastrointestinal diseases. CIRM reviewers noted that, if successfully completed, the project would likely have a major impact upon the field. His lab will develop a model of intestinal neuromuscular dysfunction that is amenable to stem cell transplantation.

Dunns novel approach to treat these patients will use stem cells reprogrammed from the patients own skin (induced pluripotent stem cells) to generate the neural system to correct the intestinal dysfunction. Dunn and his team hope the research will result in a clinical trial using patient specific induced pluripotent stem cells and provide a critical step toward an improved therapeutic approach and to treat intestinal neuromuscular dysfunction.

Dr. Dunns research was additionally supported by the National Institutes and Sun West Company.

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Two UC San Diego Scientists Receive Stem Cell Technology Grants

By LizaAVILA

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Newswise The governing board of the California Institute for Regenerative Medicine (CIRM) has awarded two University of California, San Diego researchers almost $3 million in combined funding to pursue new technologies intended to accelerate advances moving stem cell therapies out of the lab and into the clinic.

The funding was part of almost $30 million in new Tools and Technologies awards announced at CIRMs monthly meeting in San Francisco.

Sometimes even the most promising therapy can be derailed by a tiny problem, said Jonathan Thomas, JD, PhD, chair of the CIRM Board. These awards are designed to help find ways to overcome those problems, to bridge the gaps in our knowledge and ensure that the best research is able to keep progressing and move out of the lab and into clinical trials in patients.

Shaochen Chen, PhD, professor in the Department of Nanoengineering in the Jacobs School of Engineering and a member of the Institute of Engineering in Medicine at UC San Diego, received a $1.3 million in CIRM funding for development of 3D bioprinting techniques using human embryonic stem cell-derived heart muscle cells to create new cardiac tissue.

Millions of Americans suffer from cardiovascular disease, specifically congestive heart failure in which a heart valve ceases to work properly. Current treatment often calls for a valve transplant, but donor availability does not meet need.

Chen and colleagues are exploring the possibility of engineering healthy cardiac tissues bioprinted from heart muscle cells, called cardiomyocytes, created from human embryonic stem cells. These tissues could then be implanted in a damaged heart, restoring function.

Shyni Varghese, PhD, associate professor in the Department of Bioengineering at the Jacobs School of Engineering and director of the Bio-Inspired Materials and Stem Cell Engineering Laboratory, received a $1.4 CIRM grant to improve in vivo function of transplanted stem cells.

Vargheses lab focuses upon the complex interactions of cells with their surrounding microenvironment, and how the conditions necessary to promote normal, healthy survival and growth occur.

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