New research could be a breakthough in collagen and stem cell research – Truth In Aging
By daniellenierenberg
New research has identified two actives that can prevent stem cell decline as we age and increase collagen 17 levels in cells. It was published in Nature last year and has just been covered in Scientific American. The study was described as elegant by a prominent dermatologist, not involved in the project. As I am always on the look out for next big thing in antiaging skincare, I pounced.
Ill cut straight to the car chase. The two actives are Y27632 and apocynin and I was curious to see if they could be tracked down outside of a lab and, perhaps, in our potions and lotions. The first is a chemical that I havent been able to track down. Happily, I had better luck with apocynin.
Apocynin has been identified in a specific strain of cannabis, but also in cloudberry. And rubus chamaemorus (AKA cloudberry) seed oil is in a facial oil by Keracell. Ill post a link at the end of this article.
So, how do Y27632 and apocynin work? Emi Nishimura, a professor of stem cell biology at Tokyo Medical and Dental University in Japan, revealed that aging and UV exposure deplete stem cells of a crucial collagen protein. Heres what happens.
As part of normal skin health, the top layer of the epidermis is constantly being sloughed off and replaced from a self-replenishing pool of stem cells in the basal layer. These stem cells have roots that anchor them to a thin piece of tissue called the basement membrane that connects the epidermis and the dermis. Only when tethered can they replicate and mature into another type of cell.
This is where collagen 17 comes in. This collagen protein does the tethering (see the "adhesive molecule" in the illustration above), rooting the stem cell to the basement membrane. As stem cells become damaged, they lose precious amounts of collagen 17. The more protein they lose, the weaker their bond to the basement membrane, until eventually they are forced out by neighboring healthy cells.
Thats why this study is potentially a breakthrough. It has identified the process, the key protein that needs to be replenished and the chemicals that might just be able to do that.
You can find rubus chamaemorus (AKA cloudberry) seed oil and a potential source of apocynin in KERACELL Liquid Gold Enriching Elixir ($160 in the shop).
Become a member to read this article in full
Your membership includes:
Read the original here:
New research could be a breakthough in collagen and stem cell research - Truth In Aging
- Eye stem cell transplant to treat blindness bolsters retinal function in monkeys - FierceBiotech - January 14th, 2021
- Seattle researchers find clues for treatments that could eliminate HIV in infected patients - GeekWire - January 14th, 2021
- Reversing The Aging Clock With Epigenetic Reprogramming - Bio-IT World - January 14th, 2021
- Bath And Body Routines That Make You Look And Feel Good From Day To Night - Forbes - January 12th, 2021
- Worldwide Organ and Tissue Transplantation and Alternatives Industry to 2024 - Featuring Mylan, Novartis & Pfizer Among Others -... - January 12th, 2021
- BENEV Announces Investigative Report on Combination Treatment with Human Adipose Tissue Stem Cell- derived Exosomes and Fractional CO2 Laser for Acne... - January 9th, 2021
- Factor Bioscience spins out a new cell therapy player with eyes on the clinic within 2 years - Endpoints News - January 9th, 2021
- Spinogenix Wins Grant to Advance Testing of Potential Oral Therapy - ALS News Today - January 9th, 2021
- Ulta Beautys Love Your Skin Event Is Here | January 2021 - Allure - January 9th, 2021
- Exosome Therapeutic Market Overview By Size, Share, Trends, Growth Factors and Leading Players With Detailed Analysis of Industry Structure - KSU |... - January 9th, 2021
- Global Organ and Tissue Transplantation and Alternatives Market to 2024 - Impact Analysis of COVID-19 - Yahoo Finance - January 9th, 2021
- A celebrity dermat's tips for new moms on how to deal with postpartum hair and skin issues - VOGUE India - January 9th, 2021
- FOREO UFO 2 Review: Is It Worth The Hype? - GLAMOUR UK - January 9th, 2021
- The Amniotic Fluid Stem Cell Therapy Market to be synonymous to vertical growth between 2018 and 2026 - LionLowdown - January 5th, 2021
- 2021: What are the best self-care products to buy in the new year? - The Jerusalem Post - January 3rd, 2021
- The Complete Guide to Laser Treatments for Hair and Skin | The Science of Beauty Podcast | Allure - Allure - December 30th, 2020
- The big scientific breakthroughs of 2020 - The Week - December 30th, 2020
- Nociceptive neurons shown to boost hematopoiesis | 2020-12-28 - BioWorld Online - December 28th, 2020
- Getting to the root of why hair goes gray - messenger-inquirer - December 26th, 2020
- What causes chafing rash? Remedies, treatment, and prevention - Medical News Today - December 24th, 2020
- Rash on black skin: Pictures, symptoms, and treatments - Medical News Today - December 24th, 2020
- Everything You've Ever Wanted to Know About Body Hair - Allure - December 24th, 2020
- 2020 in Neuroscience, Longevity, and AIand What's to Come - Singularity Hub - December 22nd, 2020
- Hair loss, body odor, irregular periods: Covid-19 isolation does weird things to our bodies - Vox.com - December 22nd, 2020
- Scientists have restored youth to aging eyes in mice - Massive Science - December 21st, 2020
- The Adrenomyeloneuropathy Treatment Market to grow on an emphatic note from 2019 to 2029 - PharmiWeb.com - December 21st, 2020
- At 14.6% CAGR, Cell Banking Outsourcing Market 2020 Industry Analysis of Current Trends and Opportun - PharmiWeb.com - December 21st, 2020
- The Definitive Guide to All Things Vegan By Drunk Elephant - LIVEKINDLY - December 21st, 2020
- The facts about the danger of melanoma - The Hudson Reporter - December 17th, 2020
- A Tried And Tested Guide On How To Win The War Against Maskne - Forbes - December 13th, 2020
- COVID-19 and graft-versus-host disease: a tale of two diseases (and why age matters) - DocWire News - December 10th, 2020
- Avenoir Cosmetics Launches Cell Repair Serum - Clinical Strength to Enhance Skin Tone & Minimize Appearance of Sunspots, Blemishes, Discoloration,... - December 10th, 2020
- CBD: the beauty ingredient trend that can't be stopped - CosmeticsDesign.com USA - December 10th, 2020
- The Technology Behind Bone Marrow Cellular Processing: The PXP System - marketscreener.com - December 9th, 2020
- City of Hope Doctors Present Innovative Therapies to Better Treat Blood Cancers at American Society of Hematology Virtual Conference - BioSpace - December 9th, 2020
- How to Minimize Inflammation and Prevent Your Skin from Inflammaging - Coveteur - December 5th, 2020
- Reversing vision loss by turning back the aging clock - FierceBiotech - December 5th, 2020
- Clinical Trials Offer Opportunities to Change Practice to Improve Prevention and Treatment of Blood Disorders - PRNewswire - December 5th, 2020
- The Amniotic Fluid Stem Cell Therapy Market to Cascade the Success Trove - The Haitian-Caribbean News Network - December 2nd, 2020
- Global Anti-Ageing Drugs Industry Market Growth Graph To Demonstrate Inclination Towards Positive Axis By 2026 - The Courier - December 2nd, 2020
- Graft Versus Host Disease (GVHD) Patient Population, Treatment Algorithm, Medical Practices And Epidemiology Forecast To 2030 - The Market Feed - December 2nd, 2020
- The end-use Industries to Help the Medical Skin Care Products Market stand in a good stead between 2017 and 2025 - Cheshire Media - November 30th, 2020
- What exactly is the revolutionary Smart Beauty Technology, and how Kira Sorokina, the Founder of NanoAsia leads it - Press Release - Digital Journal - November 30th, 2020
- Everything to Know About Inflamm-aging - NewBeauty Magazine - November 25th, 2020
- 'This is why I'm here': A Detroit Lions VP tries to save her daughter from rare disease - ESPN - November 25th, 2020
- Israeli Scientists Discover Oxygen Beauty Treatment That Can Make You Look 25 Years Younger - All You Need to - India.com - November 25th, 2020
- Mysteries of COVID smell loss finally yield some answers - Livescience.com - November 20th, 2020
- Four life-changing wellness retreats from around the world - Euronews - November 20th, 2020
- Avrobio tracks improvements in first patient treated with Gaucher gene therapy - FierceBiotech - November 20th, 2020
- As California Passes Prop 14, What Is Stem Cell Research and Why Is It Controversial? - Newsweek - November 18th, 2020
- Mibelle Biochemistry's Ability to Introduce Breakthrough Active Ingredients for the Personal Care Market Lauded by Frost & Sullivan - PR Newswire... - November 18th, 2020
- Mibelle Biochemistry announces: Mibelle Biochemistrys Ability to Introduce Breakthrough Active Ingredients for the Personal Care Market by Frost and... - November 18th, 2020
- Real life 'Barbie and Ken' achieve doll-like looks with futuristic stem-cell injections - Daily Star - November 18th, 2020
- The Induced Pluripotent Stem Cells Market To Witness Fierce Competition Amongst The Key Players - KYT24 - November 18th, 2020
- La Prairies New Collection Is Inspired by a Platinum Meteor Shower that Lasted 200 Million Years - Surface Magazine - November 18th, 2020
- The New Generation Of Beauty - Forbes - November 18th, 2020
- The Medical Skin Care Products Market to personify growth in the next decade - PRnews Leader - November 12th, 2020
- 7 misleading 'facts' about skin that just aren't true - IOL - November 12th, 2020
- Red algae and sheep placenta: 9 bizarre but effective skincare ingredients that actually work - VOGUE India - November 12th, 2020
- Alstom SA: Availability of the half-year financial report as at 30 September 2020 - Yahoo Finance UK - November 12th, 2020
- The Adipose Tissue Derived Stem Cells market to grow in the wake of incorporation of the latest technology - The Think Curiouser - November 8th, 2020
- Cell Expansion Market Analysis, COVID-19 Impact,Outlook, Opportunities, Size, Share Forecast and Supply Demand 2021-2027|Trusted Business Insights -... - November 8th, 2020
- The Medical Skin Care Products Market to witness non-linear transition from 2017 to 2025 - PRnews Leader - November 5th, 2020
- A Review of Stem CellBased Therapies for Parkinson Disease - AJMC.com Managed Markets Network - November 5th, 2020
- Research providing better understand of graying hair | Health - Galveston County Daily News - November 5th, 2020
- Global Anti-Ageing Drugs Market (2020) to Witness Huge Growth by 2026 | La Roche-Posay, Revision Optics, Calico, Nu Skin, L'ORAL, Unity Biotechnology,... - November 5th, 2020
- Here's how to treat those brown spots on your face, chest and hands. - Mamamia - November 3rd, 2020
- Gommage (Gentle Exfoliation) Benefits, Precautions, and How to Do It - Healthline - November 3rd, 2020
- Impact Of Covid 19 On Anti-Ageing Drugs 2020 Industry Challenges Business Overview And Forecast Research Study 2026 - Zenit News - November 1st, 2020
- What is liposuction? How the procedure works and how painful it is - Business Insider India - October 31st, 2020
- The Medical Skin Care Products market to grow on a prudent note from 2017 to 2025 - TechnoWeekly - October 30th, 2020
- You Can Influence The Way Your Skin AgesHere's How - Tatler Singapore - October 30th, 2020
- Global Growth Trends and Competitive Analysis of Skin Care Cosmetic Research Report from 2020-2026 - KYT24 - October 30th, 2020
- Stem Cell Therapy Market to Register Unwavering Growth During 2025 - The Think Curiouser - October 30th, 2020
- The Medical Skin Care Products market to witness non-linear transition from 2017 to 2025 - Eurowire - October 29th, 2020
- APstem Therapeutics Announces Successful FDA INTERACT Meeting Regarding AP-Skin-01, an Off-the-Shelf Allogeneic Stem Cell Product for the Treatment of... - October 29th, 2020
- Rejuvenating Austin spa puts holistic health and wellness on the table - CultureMap Austin - October 29th, 2020
- "Peptide King" Pietro Simone Is Bringing His Treatments and Products to the US - NewBeauty Magazine - October 29th, 2020
- Next-gen skincare, silk without spiders and pollution for lunch: Meet the biotech startups pitching at IndieBios Demo Day - TechCrunch - October 29th, 2020
- Impact Of Covid-19 on Cosmetic Skin Care Market 2020 Industry Challenges, Business Overview and Forecast Research Study 2026 - PRnews Leader - October 29th, 2020
