Human Heart Cells Alter In Spaceflight But Return To Normal Quickly On Earth – Pragativadi

By daniellenierenberg

New York: Heart cells are altered in space but return to normal within 10 days on Earth, say researchers who examined the cell-level cardiac function and gene expression in human heart cells cultured aboard the International Space Station (ISS) for 5.5 weeks.

Exposure to microgravity altered the expression of thousands of genes, but largely normal patterns of gene expression reappeared within 10 days after returning to Earth, according to the study published in the journal Stem Cell Reports.

To address this question, the research team studied human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). They generated hiPSC lines from three individuals by reprogramming blood cells and then differentiated them into heart cells.

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Human Heart Cells Alter In Spaceflight But Return To Normal Quickly On Earth - Pragativadi

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