Mesenchymal stem cells and marrow stromal cells—2nd—

By Dr. Matthew Watson



Marrow stromal cells The existence of nonhematopoietic cells in bone marrow was first suggested by Cohnheim about 130 years ago [16]. To date, marrow stromal cells have been shown to differentiate into osteoblasts [17], chondrocytes [18], skeletal myocytes, adipocytes, and cardiomyocytes [19] in vitro, and thus are a useful cell source for regenerative medicine [20, 21]. Recent studies suggest that bone marrow stromal cells can also differentiate into a neuronal lineage [14], and murine bone marrow derived multipotent adult progenitor cell differentiate into dopaminergic neuronal cells [22].

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Mesenchymal stem cells and marrow stromal cells---2nd---

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