StemCell Therapy » Gene therapy

StemCell Therapy » Gene therapy http://www.stemcelltherapy.me Wed, 18 Aug 2010 08:28:46 +0000 http://wordpress.org/?v=2.9.2 en hourly 1 Breakthrough Gene Therapy Prevents Retinal Degeneration http://www.stemcelltherapy.me/breakthrough-gene-therapy-prevents-retinal-degeneration-3/ http://www.stemcelltherapy.me/breakthrough-gene-therapy-prevents-retinal-degeneration-3/#comments Wed, 18 Aug 2010 08:28:42 +0000 admin http://www.stemcelltherapy.me/breakthrough-gene-therapy-prevents-retinal-degeneration-3/ In one of only two studies of its kind, a study from researchers at Tufts University School of Medicine and the Sackler School of Graduate Biomedical Sciences at Tufts demonstrates that non-viral gene therapy can delay the onset of some forms of eye disease and preserve vision. The team developed nanoparticles to deliver therapeutic genes to the retina and found that treated mice temporarily retained more eyesight than controls. The study, published online in advance of print in Molecular Therapy, brings researchers closer to a non-viral gene therapy treatment for degenerative eye disorders… (Source: Health News from Medical News Today)

MedWorm Message: Register for MedMatcha, MedWorm’s medical advertising network, and receive $5 free advertising.

]]> http://www.stemcelltherapy.me/breakthrough-gene-therapy-prevents-retinal-degeneration-3/feed/ 0 Breakthrough gene therapy could preserve vision http://www.stemcelltherapy.me/breakthrough-gene-therapy-could-preserve-vision/ http://www.stemcelltherapy.me/breakthrough-gene-therapy-could-preserve-vision/#comments Wed, 18 Aug 2010 08:28:42 +0000 admin http://www.stemcelltherapy.me/breakthrough-gene-therapy-could-preserve-vision/ Washington, Aug 17 : Non-viral gene therapy can delay the onset of some forms of eye disease and preserve vision, found one of only two studies of its kind.

]]> http://www.stemcelltherapy.me/breakthrough-gene-therapy-could-preserve-vision/feed/ 0 Promising Results Of Gene Therapy To Treat Diseases Of The Eye http://www.stemcelltherapy.me/promising-results-of-gene-therapy-to-treat-diseases-of-the-eye-7/ http://www.stemcelltherapy.me/promising-results-of-gene-therapy-to-treat-diseases-of-the-eye-7/#comments Tue, 17 Aug 2010 08:24:17 +0000 admin http://www.stemcelltherapy.me/promising-results-of-gene-therapy-to-treat-diseases-of-the-eye-7/ The easy accessibility of the eye and the established link between specific genetic defects and ocular disorders offer hope for using gene therapy to provide long-term therapeutic benefit. Two reports in the current issue of Human Gene Therapy, a peer-reviewed journal published by Mary Ann Liebert, Inc. (www.liebertpub.com), describe the effective replacement of a …

]]> http://www.stemcelltherapy.me/promising-results-of-gene-therapy-to-treat-diseases-of-the-eye-7/feed/ 0 Gene Therapy To Treat Diseases Of The Eye http://www.stemcelltherapy.me/gene-therapy-to-treat-diseases-of-the-eye-3/ http://www.stemcelltherapy.me/gene-therapy-to-treat-diseases-of-the-eye-3/#comments Tue, 17 Aug 2010 08:24:17 +0000 admin http://www.stemcelltherapy.me/gene-therapy-to-treat-diseases-of-the-eye-3/ The easy accessibility of the eye and the established link between specific genetic defects and ocular disorders offer hope for using gene therapy to provide long-term therapeutic benefit. Two reports in the current issue of Human Gene Therapy, a peer-reviewed journal published by Mary Ann Liebert, Inc., describe the effective replacement of a human gene to preserve photoreceptor function in a …

]]> http://www.stemcelltherapy.me/gene-therapy-to-treat-diseases-of-the-eye-3/feed/ 0 Effects of Antisense Transforming Growth Factor-beta1 Gene Transfer on the Biological Activities of Tendon Sheath Fibroblasts. http://www.stemcelltherapy.me/effects-of-antisense-transforming-growth-factor-beta1-gene-transfer-on-the-biological-activities-of-tendon-sheath-fibroblasts/ http://www.stemcelltherapy.me/effects-of-antisense-transforming-growth-factor-beta1-gene-transfer-on-the-biological-activities-of-tendon-sheath-fibroblasts/#comments Tue, 17 Aug 2010 08:24:16 +0000 admin http://www.stemcelltherapy.me/effects-of-antisense-transforming-growth-factor-beta1-gene-transfer-on-the-biological-activities-of-tendon-sheath-fibroblasts/ Authors: Xia C, Ding C, Yang X, Sun K, Tian S
Recent studies have shown the importance of transforming growth factor-beta (TGF-beta) in flexor tendon wound healing. Decreased adhesion formation and increased range of motion after the administration of TGF-beta antibodies after tendon repair have been shown. But TGF-beta antibodies have a short biologic half-life, and continuous supplementation of exogenous TGF-beta antibodies is not practical. Transfer of growth factor genes to tenocytes provides an alternative to protein therapeutics, and a gene therapy approach will prolong the availability of therapeutic proteins.We investigated the biological activities effects of rabbit tendon sheath fibroblasts transfected by antisense TGF-beta1 gene. Tendon sheath fibroblasts were isolated from …

]]> http://www.stemcelltherapy.me/effects-of-antisense-transforming-growth-factor-beta1-gene-transfer-on-the-biological-activities-of-tendon-sheath-fibroblasts/feed/ 0 Gene Therapy To Treat Diseases Of The Eye http://www.stemcelltherapy.me/gene-therapy-to-treat-diseases-of-the-eye/ http://www.stemcelltherapy.me/gene-therapy-to-treat-diseases-of-the-eye/#comments Tue, 17 Aug 2010 08:24:16 +0000 admin http://www.stemcelltherapy.me/gene-therapy-to-treat-diseases-of-the-eye/ The easy accessibility of the eye and the established link between specific genetic defects and ocular disorders offer hope for using gene therapy to provide long-term therapeutic benefit. Two reports in the current issue of Human Gene Therapy, a peer-reviewed journal published by Mary Ann Liebert, Inc., describe the effective replacement of a human gene to preserve photoreceptor function in a mouse model of severe retinal degeneration. The articles are available free online here… (Source: Health News from Medical News Today)

]]> http://www.stemcelltherapy.me/gene-therapy-to-treat-diseases-of-the-eye/feed/ 0 Promising results of gene therapy to treat diseases of the eye http://www.stemcelltherapy.me/promising-results-of-gene-therapy-to-treat-diseases-of-the-eye-5/ http://www.stemcelltherapy.me/promising-results-of-gene-therapy-to-treat-diseases-of-the-eye-5/#comments Tue, 17 Aug 2010 08:24:16 +0000 admin http://www.stemcelltherapy.me/promising-results-of-gene-therapy-to-treat-diseases-of-the-eye-5/ The easy accessibility of the eye and the established link between specific genetic defects and ocular disorders offer hope for using gene therapy to provide long-term therapeutic benefit. Two new reports describe the effective replacement of a human gene to preserve photoreceptor function in a mouse model of severe retinal degeneration. (Source: ScienceDaily Headlines)

MedWorm Message: Register for MedMatcha, MedWorm’s medical advertising network, and receive $5 free advertising.

]]> http://www.stemcelltherapy.me/promising-results-of-gene-therapy-to-treat-diseases-of-the-eye-5/feed/ 0 Breakthrough gene therapy prevents retinal degeneration http://www.stemcelltherapy.me/breakthrough-gene-therapy-prevents-retinal-degeneration/ http://www.stemcelltherapy.me/breakthrough-gene-therapy-prevents-retinal-degeneration/#comments Tue, 17 Aug 2010 08:24:16 +0000 admin http://www.stemcelltherapy.me/breakthrough-gene-therapy-prevents-retinal-degeneration/ ( Tufts University, Health Sciences ) In one of only two studies of its kind, a study from researchers at Tufts University demonstrates that non-viral gene therapy can delay the onset of some forms of eye disease and preserve vision. The team developed nanoparticles to deliver therapeutic genes to the retina and found that treated mice temporarily retained more eyesight than controls. The study …

]]> http://www.stemcelltherapy.me/breakthrough-gene-therapy-prevents-retinal-degeneration/feed/ 0 Promising Results Of Gene Therapy To Treat Diseases Of The Eye http://www.stemcelltherapy.me/promising-results-of-gene-therapy-to-treat-diseases-of-the-eye-6/ http://www.stemcelltherapy.me/promising-results-of-gene-therapy-to-treat-diseases-of-the-eye-6/#comments Tue, 17 Aug 2010 08:24:16 +0000 admin http://www.stemcelltherapy.me/promising-results-of-gene-therapy-to-treat-diseases-of-the-eye-6/ The easy accessibility of the eye and the established link between specific genetic defects and ocular disorders offer hope for using gene therapy to provide long-term therapeutic benefit. Two reports in the current issue of Human Gene Therapy, a peer-reviewed journal published by Mary Ann Liebert, Inc. (www.liebertpub.com), describe the effective replacement of a …

]]> http://www.stemcelltherapy.me/promising-results-of-gene-therapy-to-treat-diseases-of-the-eye-6/feed/ 0 Breakthrough gene therapy prevents retinal degeneration http://www.stemcelltherapy.me/breakthrough-gene-therapy-prevents-retinal-degeneration-2/ http://www.stemcelltherapy.me/breakthrough-gene-therapy-prevents-retinal-degeneration-2/#comments Tue, 17 Aug 2010 08:24:16 +0000 admin http://www.stemcelltherapy.me/breakthrough-gene-therapy-prevents-retinal-degeneration-2/ In one of only two studies of its kind, scientists demonstrate that non-viral gene therapy can delay the onset of some forms of eye disease and preserve vision. The team developed nanoparticles to deliver therapeutic genes to the retina and found that treated mice temporarily retained more eyesight than controls. The study brings researchers closer to a non-viral gene therapy treatment for …

]]> http://www.stemcelltherapy.me/breakthrough-gene-therapy-prevents-retinal-degeneration-2/feed/ 0 Gene Therapy To Treat Diseases Of The Eye http://www.stemcelltherapy.me/gene-therapy-to-treat-diseases-of-the-eye-2/ http://www.stemcelltherapy.me/gene-therapy-to-treat-diseases-of-the-eye-2/#comments Tue, 17 Aug 2010 08:24:16 +0000 admin http://www.stemcelltherapy.me/gene-therapy-to-treat-diseases-of-the-eye-2/ The easy accessibility of the eye and the established link between specific genetic defects and ocular disorders offer hope for using gene therapy to provide long-term therapeutic benefit. Two reports in the current issue of Human Gene Therapy, a peer-reviewed journal published by Mary Ann Liebert, Inc., describe the effective replacement of a human gene to preserve photoreceptor function in a …

]]> http://www.stemcelltherapy.me/gene-therapy-to-treat-diseases-of-the-eye-2/feed/ 0 Non-viral gene therapy delays onset of eye disease http://www.stemcelltherapy.me/non-viral-gene-therapy-delays-onset-of-eye-disease/ http://www.stemcelltherapy.me/non-viral-gene-therapy-delays-onset-of-eye-disease/#comments Tue, 17 Aug 2010 05:50:06 +0000 admin http://www.stemcelltherapy.me/non-viral-gene-therapy-delays-onset-of-eye-disease/ In one of only two studies of its kind, a study from researchers at Tufts University School of Medicine and the Sackler School of Graduate Biomedical Sciences at Tufts demonstrates that non-viral gene therapy can delay the onset of some forms of eye disease and preserve vision. The team developed nanoparticles to deliver therapeutic genes to the retina and found that treated mice temporarily …

]]> http://www.stemcelltherapy.me/non-viral-gene-therapy-delays-onset-of-eye-disease/feed/ 0 Study finds no link among estrogen and lung cancer mortality in postmenopausal women http://www.stemcelltherapy.me/study-finds-no-link-among-estrogen-and-lung-cancer-mortality-in-postmenopausal-women/ http://www.stemcelltherapy.me/study-finds-no-link-among-estrogen-and-lung-cancer-mortality-in-postmenopausal-women/#comments Mon, 16 Aug 2010 07:04:56 +0000 admin http://www.stemcelltherapy.me/study-finds-no-link-among-estrogen-and-lung-cancer-mortality-in-postmenopausal-women/ Use of estrogen alone did not increase lung cancer mortality in postmenopausal women, according to a study published online August 13 in The Journal of the National Cancer Institute. In the Women’s Health Initiative (WHI) trial, which consisted of several clinical trials on postmenopausal women, one study showed women with previous hysterectomy taking combined estrogen plus progestin therapy had …

]]> http://www.stemcelltherapy.me/study-finds-no-link-among-estrogen-and-lung-cancer-mortality-in-postmenopausal-women/feed/ 0 Scientists discover new signaling pathway to reduce tumour growth in glioblastoma multiforme http://www.stemcelltherapy.me/scientists-discover-new-signaling-pathway-to-reduce-tumour-growth-in-glioblastoma-multiforme/ http://www.stemcelltherapy.me/scientists-discover-new-signaling-pathway-to-reduce-tumour-growth-in-glioblastoma-multiforme/#comments Mon, 16 Aug 2010 05:35:06 +0000 admin http://www.stemcelltherapy.me/scientists-discover-new-signaling-pathway-to-reduce-tumour-growth-in-glioblastoma-multiforme/ Malignant gliomas are the most common subtype of primary brain tumor – and one of the deadliest. Even as doctors make steady progress treating other types of solid tumor cancers, from breast to prostate, the most aggressive form of malignant glioma, called a glioblastoma multiforme or GBM, has steadfastly defied advances in neurosurgery, radiation therapy and various conventional or novel drugs …

]]> http://www.stemcelltherapy.me/scientists-discover-new-signaling-pathway-to-reduce-tumour-growth-in-glioblastoma-multiforme/feed/ 0 Scientists discover genetic alteration in Kabuki syndrome http://www.stemcelltherapy.me/scientists-discover-genetic-alteration-in-kabuki-syndrome/ http://www.stemcelltherapy.me/scientists-discover-genetic-alteration-in-kabuki-syndrome/#comments Mon, 16 Aug 2010 05:05:16 +0000 admin http://www.stemcelltherapy.me/scientists-discover-genetic-alteration-in-kabuki-syndrome/ Using a new, rapid and less expensive DNA sequencing strategy, scientists have discovered genetic alterations that account for most cases of Kabuki syndrome, a rare disorder that causes multiple birth defects and mental retardation. Instead of sequencing the entire human genome, the new approach sequences just the exome, the 1-2 percent of the human genome that contains protein-coding genes.

]]> http://www.stemcelltherapy.me/scientists-discover-genetic-alteration-in-kabuki-syndrome/feed/ 0 Common genetic variation in HLA region associated with late onset sporadic Parkinson’s disease: Research http://www.stemcelltherapy.me/common-genetic-variation-in-hla-region-associated-with-late-onset-sporadic-parkinsons-disease-research/ http://www.stemcelltherapy.me/common-genetic-variation-in-hla-region-associated-with-late-onset-sporadic-parkinsons-disease-research/#comments Mon, 16 Aug 2010 04:50:06 +0000 admin http://www.stemcelltherapy.me/common-genetic-variation-in-hla-region-associated-with-late-onset-sporadic-parkinsons-disease-research/ A team of researchers has discovered new evidence that Parkinson’s disease may have an infectious or autoimmune origin. “Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson’s disease” appears online in Nature Genetics.

]]> http://www.stemcelltherapy.me/common-genetic-variation-in-hla-region-associated-with-late-onset-sporadic-parkinsons-disease-research/feed/ 0 Promising results of gene therapy to treat diseases of the eye http://www.stemcelltherapy.me/promising-results-of-gene-therapy-to-treat-diseases-of-the-eye-3/ http://www.stemcelltherapy.me/promising-results-of-gene-therapy-to-treat-diseases-of-the-eye-3/#comments Mon, 16 Aug 2010 03:17:43 +0000 admin http://www.stemcelltherapy.me/promising-results-of-gene-therapy-to-treat-diseases-of-the-eye-3/ The easy accessibility of the eye and the established link between specific genetic defects and ocular disorders offer hope for using gene therapy to provide long-term therapeutic benefit. Two new reports describe the effective replacement of a human gene to preserve photoreceptor function in a mouse model of severe retinal degeneration.

]]> http://www.stemcelltherapy.me/promising-results-of-gene-therapy-to-treat-diseases-of-the-eye-3/feed/ 0 Promising results of gene therapy to treat diseases of the eye http://www.stemcelltherapy.me/promising-results-of-gene-therapy-to-treat-diseases-of-the-eye-4/ http://www.stemcelltherapy.me/promising-results-of-gene-therapy-to-treat-diseases-of-the-eye-4/#comments Mon, 16 Aug 2010 03:17:43 +0000 admin http://www.stemcelltherapy.me/promising-results-of-gene-therapy-to-treat-diseases-of-the-eye-4/ The easy accessibility of the eye and the established link between specific genetic defects and ocular disorders offer hope for using gene therapy to provide long-term therapeutic benefit. Two new reports describe the effective replacement of a human gene to preserve photoreceptor function in a mouse model of severe retinal degeneration.

]]> http://www.stemcelltherapy.me/promising-results-of-gene-therapy-to-treat-diseases-of-the-eye-4/feed/ 0 Bay Area families lead research efforts for Rett Syndrome http://www.stemcelltherapy.me/bay-area-families-lead-research-efforts-for-rett-syndrome/ http://www.stemcelltherapy.me/bay-area-families-lead-research-efforts-for-rett-syndrome/#comments Mon, 16 Aug 2010 02:16:58 +0000 admin http://www.stemcelltherapy.me/bay-area-families-lead-research-efforts-for-rett-syndrome/ Rett syndrome is one of thousands of genetic disorders in existence — but one of the few many people believe will soon be reversible. Scientists were able to reverse symptoms of the neurodevelopmental disorder in mice in 2007, giving hope to families everywhere.

]]> http://www.stemcelltherapy.me/bay-area-families-lead-research-efforts-for-rett-syndrome/feed/ 0 Enhanced Long-Term Transduction and Multilineage Engraftment of Human Hematopoietic Stem Cells Transduced with Tyrosine-Modified Recombinant Adeno-Associated Virus Serotype 2 http://www.stemcelltherapy.me/enhanced-long-term-transduction-and-multilineage-engraftment-of-human-hematopoietic-stem-cells-transduced-with-tyrosine-modified-recombinant-adeno-associated-virus-serotype-2/ http://www.stemcelltherapy.me/enhanced-long-term-transduction-and-multilineage-engraftment-of-human-hematopoietic-stem-cells-transduced-with-tyrosine-modified-recombinant-adeno-associated-virus-serotype-2/#comments Sun, 15 Aug 2010 08:18:49 +0000 admin http://www.stemcelltherapy.me/enhanced-long-term-transduction-and-multilineage-engraftment-of-human-hematopoietic-stem-cells-transduced-with-tyrosine-modified-recombinant-adeno-associated-virus-serotype-2/ Human Gene Therapy , Vol. 0, No. 0. (Source: Human Gene Therapy)

MedWorm Message: Register for MedMatcha, MedWorm’s medical advertising network, and receive $5 free advertising.

]]> http://www.stemcelltherapy.me/enhanced-long-term-transduction-and-multilineage-engraftment-of-human-hematopoietic-stem-cells-transduced-with-tyrosine-modified-recombinant-adeno-associated-virus-serotype-2/feed/ 0