Washington, Feb 14 (ANI): Researchers have conducted a stem cell study in mice, which suggests a novel strategy for treating damaged cardiac tissue in patients following a heart attack. The approach potentially could improve cardiac function, minimize scar size, lead to the development of new blood vessels – and avoid the risk of tissue rejection. In the investigation, the researchers isolated and characterized a novel type of cardiac stem cell from the heart tissue of middle-aged mice following a heart attack.

In the investigation, reported online in the journal PLoS ONE, the researchers isolated and characterized a novel type of cardiac stem cell from the heart tissue of middle-aged mice following a heart attack. Then, in one experiment, they placed the cells in the culture dish and showed they had the ability to differentiate into cardiomyocytes, or “beating heart cells,” as well as endothelial cells and smooth muscle cells, all of which make up the heart.

Stem cells harvested from a patient's own heart can be used to help repair muscle damaged during a heart attack, according to a preliminary study published online Monday in The Lancet. While it's too soon to know if the technique will help patients live longer, the study is the second small, promising study of cardiac stem cells in three months

Stem cells help regrow heart tissue in study While it?s too soon to know if the technique will help patients live longer, the study is the second small, promising study of cardiac stem cells in three months. A link to this page will be included in your message

SAN FRANCISCO — Stem cells grown from patients' own cardiac tissue can heal damage once thought to be permanent after a heart attack, according to a study that suggests the experimental approach may one day help stave off heart failure. In a trial of 25 heart-attack patients, 17 who got the stem cell treatment showed a 50 percent reduction in cardiac scar tissue compared with no improvement for the eight who received standard care. The results were published Tuesday in the medical journal Lancet.

February 15, 2012, 12:06 AM EST By Ryan Flinn (Adds comment from researcher in 13th paragraph.) Feb. 14 (Bloomberg) — Stem cells grown from patients’ own cardiac tissue can heal damage once thought to be permanent after a heart attack, according to a study that suggests the experimental approach may one day help stave off heart failure. In a trial of 25 heart-attack patients, 17 who got the stem cell treatment showed a 50 percent reduction in cardiac scar tissue compared with no improvement for the eight who received standard care.

Featured Article Academic Journal Main Category: Stem Cell Research Also Included In: Cardiovascular / Cardiology Article Date: 14 Feb 2012 – 2:00 PST email to a friend   printer friendly   opinions   Current Article Ratings: Patient / Public: 5 (1 votes) Healthcare Prof: Details of a small clinical trial published in The Lancet on Tuesday reveal how scientists helped patients with hearts damaged by heart attack to re-grow healthy heart muscle and reduce scar tissue with an infusion of stem cells taken from the patients' own hearts. Leading international cardiologist and heart researcher Dr Eduardo Marbán, who is director of the Cedars-Sinai Heart Institute in Los Angeles and Mark S. Siegel Family Professor, is senior author of the study.

Even after recovery, heart attacks can leave a lasting mark on your ticker—scar tissue weakens the muscle and prevents it from functioning as well as it did before seizing up. A pioneering stem-cell procedure, however, could cut the damage in half. According to the results of a small safety trial by the Cedars-Sinai Heart Institute and published in the Lancet medical journal, introducing stem cells derived from the patient's own heart have shown an “unprecedented” ability to reduce scarring as well as regenerate healthy cardiac tissue.

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Public release date: 13-Feb-2012 [ | E-mail | Share ] Contact: Sally Stewart sally.stewart@cshs.org 310-248-6566 Cedars-Sinai Medical Center Results from a Cedars-Sinai Heart Institute clinical trial show that treating heart attack patients with an infusion of their own heart-derived cells helps damaged hearts re-grow healthy muscle.

Stem cells grown from patients’ own cardiac tissue can heal damage once thought to be permanent after a heart attack, according to a study that suggests the experimental approach may one day help stave off heart failure. In a trial of 25 heart-attack patients, 17 who got the stem cell treatment showed a 50 percent reduction in cardiac scar tissue compared with no improvement for the eight who received standard care. The results, from the first of three sets of clinical trials generally needed for regulatory approval, were published today in the medical journal Lancet

Heart-Attack Damage Heals After Stem Cell Treatment Feb.

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They also help to reduce scar size Infusion of cardiac stem cells into persons who suffered heart attack recently can help to regenerate their heart muscles, says a study published on February 14, in The Lancet. Phase I of the study was conducted on 17 patients, who received stems cells, and eight, who received standard care (control group), at the Cedars-Sinai Heart Institute in Los Angeles and Johns Hopkins Hospital, Baltimore. All of them had had heart attacks about a month before the study began in May 2009

30-01-2012 06:10 Professor Michael Schneider of Imperial College tells Alan Keys about how stem cell research is leading to treatments for heart disease. Michael describes how the availability of stem cells allows his team to determine the molecules involved in heart cell death and also how to protect those cells from death during a heart attack. Michael foresees a near future where stem cells are combined with other therapies to both repair hearts and enable hearts to self-repair

13-01-2012 08:41 This is human heart muscle in a dish, beating spontaneously. It was made by Dr Lei Ye of the Stem Cell Institute from human induced pluripotent stem cells (hiPSC). These were made by our iPSC facility from human skin cells into which 4 specific genes were temporarily introduced.

14-12-2011 20:22 Human tissue cells derived from induced pluripotent stem (iPS) cells recapitulate many of the characteristics and functionality expected of in vivo cell types. iCell® Cardiomyocytes are derived from human IPS cells and are currently being used in both drug discovery and basic research in Industrial and Academic settings. Dr.

Posted: Monday, February 6, 2012 10:00 am | Updated: 11:50 am, Mon Feb 6, 2012. Researchers at Rice University and Texas Children's Hospital have turned stem cells from amniotic fluid into cells that form blood vessels

29-01-2012 23:26 Fourteen patients were randomized to see if adipose-derived adult stem cells would help limit the damage from an acute heart attack. Infarct size was decreased by 50%, the perfusion defect was 17% smaller, and the left ventriclular ejection fraction was increased about 6% better than the control group. Stem cell vocabulary was reviewed and highlighted that there are embryonic stem cells and adult stem cells and that sources of stem cell are from bone marrow, adipose tissue, blood, umbilical cord blood and from cloned embryonic cell lines

Researchers at Rice University and Texas Children's Hospital have made major strides in repairing damaged infant hearts using stem cells, the two institutions announced Monday morning